[Breast reconstruction: a viewpoint].
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Biomedical subjects
Publications and source records attributed to S Krupp.
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A study of 34 reconstructive or aesthetic operations done with supplemented local anaesthesia (local anaesthesia associated with a premedication of methadone, midazolam and droperidol) is presented. Results of this anaesthesia were good in 88% as judged by the surgeon. The immediate post-operative impression was indifferent to pleasant in 85% of the patients. A few months later on, 72% of this cohort of patients would accept a new operation with the same kind of anaesthesia. Although these results are good, ways of improving the results are discussed.
Tissue expansion is a useful tool in reconstructive surgery. It permits the correction of large skin lesions by expanded cutaneous or fascio-cutaneous flaps, well vascularised and matching in colour, texture and thickness. We report our results in 12 children. There was a relatively high complication rate.
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Transplantation of autologous cultured epidermal sheets is a recent advance in the treatment of burn patients. A small skin biopsy is sufficient to produce large epidermal sheets within 3 weeks which provide transplants to cover extensive burn wounds. First clinical experience with this method is described.
Miscellaneous cardiac abnormalities can occur after electrical burns. The long term outcomes are still unknown. We studied 10 patients, 9 of whom suffered high-voltage electrocution, and one of whom was struck by lightning. Serial electrocardiograms (ECG) and serum MB creatine phosphokinase isoenzyme (MB-CPK) activities were obtained during their stay in hospital. ECG and thallium 201 cardiac scintigraphy at rest, as well as echocardiograms were obtained in all patients 4 to 48 months after discharge. In hospital, 9 patients showed one or more abnormal findings at physical examination (4 cases), ECG (8 cases), MB-CPK (1 case). At long term follow-up, 5 patients had one or more myocardial functions or conduction abnormalities, with or without symptoms. One patient had compensated heart failure. Nine patients were asymptomatic. Abnormal ECG findings persisted in 3 patients. Three cardiac scans showed evidence of regional myocardial hypoperfusion. Decreases in left ventricular indices measured by echocardiogram were found in 3 patients. We conclude that high-voltage electrocution is associated with a high incidence of cardiac abnormalities, which may persist. Long term evaluation, requiring cardiac T1 201 scintigraphy and echocardiogram, may be justified.
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Free vascularized transfers have recently provided new perspectives on soft tissue replacement. Their main advantage over conventional pedicle flaps is the shortened hospital stay and overall treatment, particularly in traumatic injuries of the lower leg. Our review of 15 consecutive cases of free flaps show a high rate of early complications (33% surgical revision) and a low rate of failure (1 partial loss). The indications for a free flap versus pedicle flap are discussed, as well as the choice of a skin flap or muscle flap or musculocutaneous flap, with regard to their results and their consequences at the donor site.
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A prerequisite to a successful secondary cleft lip and nose repair is the proper alignment of the upper and lower jaw in occlusion. A wise choice of up to date techniques for secondary correction of cleft lip and nose deformities provides good to excellent results. These are facilitated by transplantation of cartilage from the ear.
Biopsies are useful for monitoring wound infection. Not only does this method have a diagnostic value, but it also helps to evaluate the effectiveness of local and systemic wound treatment, to determine the appropriate time of skin autografting and finally to assess the chance of survival.
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For reconstruction of traumatic defects, choosing the most suitable free flap and vessels for microvascular anastomoses is paramount. Careful clinical examination, followed by a Doppler-ultrasonography and arteriography is mandatory. An end-to-end anastomosis is desirable if the artery is interrupted distally. In all other cases end-to-side anastomoses should be used since they do not compromise distal blood flow. In the case of the "chinese" forearm free flap, one should always reconstruct the donor radial artery with a vein graft to assure optimal blood supply of the hand. This free flap should not be used in the rare cases where the arterial arcade of the hand is absent.
Since 1971 we have been covering pressure sores and unstable scars with transposition-rotation--muscle and musculocutaneous flaps, thereby padding the cavity resulting from excision of bone and scar tissue. The long term results compare favourably with classical random pattern skin flaps. From the beginning of 1980 we have been using the sensory innervated tensor fascia lata myodermal flap for the ischial region. This provides sensation for a formerly insensitive area in patients suffering from a spinal cord lesion below L3/4.
The management of burn scars of the trunk is discussed, in respect of the specific problems related to different areas such as the axilla, thorax and back, the female breast and the perineum as well as the external genitalia. Special emphasis is placed on the different aspects of burn sequelae of the female breast with regard to pre- and postpuberty age. The prevention and therapy of the burn scar carcinoma are dealt with.
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