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Biomedical subjects

S Kristensen

Publications and source records attributed to S Kristensen.

At least 109 records · Page 6Linked to original sources
PubMed1983

Prostaglandins, renin, aldosterone, and catecholamines in preeclampsia.

Urinary excretion of prostaglandin E2 (PGE2) and F2 alpha (PGF2 alpha), plasma concentrations of renin (PRC), aldosterone (PAC), noradrenaline (PNA) and adrenaline (PA) were determined in the third trimester of pregnancy, 5 days and 3 months after delivery in preeclampsia and normotensive pregnant and non-pregnant control subjects. PGE2 was higher in pregnant control subjects than in non-pregnant subjects, but reduced to non-pregnant level in preeclampsia. PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group. PRC and PAC were increased during pregnancy, but considerably lesser in preeclampsia than during normotensive pregnancy. PNA and PA were the same in all three groups. All parameters were normal 3 months after delivery. There were no correlations between any of the hormones and blood pressure in any of the groups. PGE2 was positively correlated to PRC. The lack of renal PGE2 in preeclampsia might be responsible for the decrease in renal blood flow and sodium excretion, and the changes in PRC and PAC are supposed to be secondary to changes in PGE2. It is hypothesised that preeclampsia is a state of prostaglandin deficiency.

Aldosterone↗
PubMed1983

Role of fixation in the treatment of nasal fractures.

Following the reduction of nasal fractures, fixation was performed in 3 ways: 1 Packing for 72 h and plaster cast for 1 week. 2 Packing for 72 h and adhesive tape for 1 week. 3 Adhesive tape for 1 week. At follow-up 3 months after the reduction, these groups were compared with a group of patients with nasal fractures which had not needed treatment and with a group of normals. It was concluded that among the group fixed with packing and plaster cast, significantly fewer patients were dissatisfied than in the other groups, and fewer complained of deformity. The physical examination showed an appreciable number of minor deformities in all groups including the normal group. A significantly higher frequency of nasal obstruction was found in the group of patients operated upon compared to the non-operated group and the normal group by physical examination, but not by the questionnaire. The present study does not support the point of view that a high percentage of cases of nasal fracture have to be operated upon by open reduction. Radiology has no medical or legal value in patients with nasal fractures and should not be used.

Adolescent↗
PubMed1983

The influence of normotensive pregnancy and pre-eclampsia on angiotensin-converting enzyme.

Serum angiotensin-converting enzyme (SACE) levels were determined in normotensive pregnant subjects and patients with pre-eclampsia in the third trimester of pregnancy and 5 days, 3 and 6 months after parturition, and also in the first and second trimester in the normotensive group. SACE levels were reduced during pregnancy and 5 days after delivery in the normotensive subjects compared with the levels 3 and 6 months after delivery and to the non-pregnant control subjects. After correction for plasma volume expansion, SACE was reduced in first and second trimester only. In pre-eclampsia both SACE and corrected SACE were significantly lower in third trimester and 5 days after parturition than 3 and 6 months after delivery and in non-pregnant control subjects. The reason for the reduced level of SACE in first and second trimester during normal pregnancy is not known. The low SACE levels in pre-eclampsia may be a secondary phenomenon due to a decreased placental synthesis without primary importance for the blood pressure regulation.

Adolescent↗
PubMed1982

Plasma noradrenaline and adrenaline in pre-eclampsia, essential hypertension in pregnancy and normotensive pregnant control subjects.

Noradrenaline and adrenaline in plasma were determined in 15 patients with pre-eclampsia, 10 pregnant patients with essential hypertension, 2 patients with transient hypertension in pregnancy, 11 normotensive pregnant control subjects, and 16 non-pregnant normotensive control subjects. Measurements were performed in the second and third trimester, 5 days, and 3 months after delivery. Comparison within groups showed no significant differences in plasma noradrenaline or adrenaline between levels in pregnancy, 5 days after delivery, and 3 months after delivery in neither pre-eclampsia, essential hypertension nor normotensive pregnant control subjects. Comparison between groups showed no significant differences between the levels in pre-eclampsia, essential hypertension and normotensive pregnant control subjects, neither in pregnancy nor after delivery. Plasma noradrenaline and adrenaline in pregnancy were the same as in normotensive non-pregnant control subjects. Plasma noradrenaline and blood pressure were not correlated in any of the groups. It is concluded that the sympathetic adrenergic activity evaluated by plasma catecholamines is normal in patients with pre-eclampsia and pregnant patients with essential hypertension.

Adolescent↗
PubMed1982

Prostaglandins, catecholamines, renin and aldosterone during hypertensive and normotensive pregnancy.

Urinary excretion of prostaglandin E2 (PGE2) and F2 alpha (PGF2 alpha), plasma concentrations of renin (PRC), aldosterone (PAC), noradrenaline (PNA) and adrenaline (PA) were determined in the third trimester of pregnancy, 5 days and 3 months after delivery in preeclampsia and normotensive pregnant and non-pregnant control subjects. PGE2 was higher in pregnant control subjects than in non-pregnant subjects, but reduced to non-pregnant level in preeclampsia. PGF2 alpha was the same in preeclampsia and normotensive pregnancy but higher than in the non-pregnant group. PRC and PAC were increased during pregnancy, but considerably lesser in preeclampsia than during normotensive pregnancy. PNA and PA were the same in all three groups. All parameters were normal 3 months after delivery. There were no correlations between any of the hormones and blood pressure in any of the groups. PGE2 was positively correlated to PRC. The lack of renal PGE2 in preeclampsia might be responsible for the decrease in renal blood flow and sodium excretion, and the changes in PRC and PAC are supposed to be secondary to changes in PGE2. It is hypothesised that preeclampsia is a state of prostaglandin deficiency.

Aldosterone↗
PubMed1981

The effect of corticosteroid therapy on infection with Toxocara canis in dogs.

Three, six-month-old dogs were infected with 2,000 eggs of Toxocara canis. Three weeks after infection 15 immature adult parasites were found in the intestine of the dog which had been treated with high doses of corticosteroids (2 ml of Opticortenol S given every four days) while no parasites were found in the intestine of the dog treated with repeated injections of 0.3 ml Opticortenol S or in the untreated control dog. The increased susceptibility to infection with T. canis in the dog treated with high doses of corticosteroids was associated with a decrease in in vitro lymphocyte responsiveness to the mitogen concanavalin A and pokeweed mitogen and with a complete suppression of the eosinophilia that was seen 10 days after infection in the untreated control dog.

Animals↗
PubMed1981

A study of skin diseases in dogs and cats. VI. Microflora of the major canine pyodermas.

From 40 dogs with pyoderma swabs from areas with representative lesions were examined bacteriologically. Staph. aureus was found in 98% of the areas, beta-hemolytic streptococci in 30%, and Gram-negative organisms, mainly Proteus spp., in 30% (Table I). Pure infection with Staph. aureus was found in 55% of the areas. Staph. aureus and beta-hemolytic streptococci were found in 15%, Staph. aureus and Gram-negative organisms in 15%, Staph. aureaus and beta-hemolytic streptococci as well as Gram-negative organisms in 13%, and beta-hemolytic streptococci and Gram-negative organisms in 3% (Table II). Compared to normal and eczematous skin areas, Staph. aureus was found more often, and in greater numbers, in areas with pyoderma, whereas micrococci, alpha-hemolytic streptococci, and Acinetobacter spp. were rarer. Gram-negative organisms such as Proteus spp., E. coli, and Pseudomonas spp. were found with equal frequency in eczema and pyoderma, while beta-hemolytic streptococci were almost exclusively associated with suppurative lesions (Tables IV and V).

Acinetobacter↗
PubMed1981

A study of skin diseases in dogs and cat. VII. Ringworm infection.

During 1973 through 1979 a total of 774 specimens from dogs and 227 specimens from cats were submitted for examination for ringworm infection. Ninety-six (12.4%) of the samples from dogs and 66 (29.1%) of the samples from cats were positive by culture (Tables I and II). Microsporum canis accounted for all infections in cats and for 95.8% of the infections in dogs. Four dogs (4.2%) were infected with Trichophyton mentagrophytes. Three fourths of the infections with M. canis were diagnosed during August through January (Fig. 1). Ringworm infections can be diagnosed by direct microscopy of hair and scrapings. Wood's lamp examination, skin biopsy, and culture. Of these, the latter method is the most reliable.

Animals↗
PubMed1979

Systemic lupus erythematosus--a zoonosis?

The medical history was obtained and a physical examination carried out--in addition to an immunological investigation of the blood and skin--on 11 dogs in the ownership of patients with systemic lupus erythematosus (SLE). The results were compared with those obtained from a control group and it was found that they do not support the hypothesis that SLE is a zoonosis.

Animals↗
PubMed1979

[Infection in man and dog with the mite, Cheyletiella yasguri Smiley].

The infection with the mite Cheyletiella yasguri Smiley in 3 dogs and 5 out of 6 persons exposed to infestation is reported. Two of the dogs appeared to have been infected during a stay in a kennel. The dogs presented with moderate itching and slight to massive floury squamation on the back. In the infected persons, excoriated papules were present on the body and the extremities. The itching, which had persisted for 4--12 months, disappeared in all cases a few days after the dogs had been removed from the house. In the dogs, three antiparasitic baths were sufficient to exterminate the mite population.

Adult↗