[Bland-White-Garland Syndrome].
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Biomedical subjects
Publications and source records attributed to S Kazama.
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To evaluate the effects of deflation timing of an intraaortic balloon (IAB) on ventriculoarterial (VA) coupling and left ventricular (LV) mechanics, we assessed contractility: Emax (mmHg/ml); VA coupling: Ea/Ees; myocardial oxygen consumption: LV pressure-volume area (PVA); and energy efficiency: external work (EW)/PVA during IAB pumping, using four different timing intervals of IAB deflation in eight dogs weighing 19.8 +/- 3.8 kg. In the conventional timing group (G-conv), the IAB was deflated before LV systole. In the real time group (G-1, 2, 3), the IAB was deflated during isovolumic contraction (ICP), and the group was subdivided into three groups based on time of deflation: G-1 at the onset of ICP, G-2 at the midpoint of ICP, and G-3 at the end of ICP. Percent changes in values with IAB compared to those without assist were calculated. Based on the results, IAB deflation during ICP reduces LV end-systolic pressure and significantly optimizes VA coupling and LV efficiency during IAB support, compared with conventional timing.