Search PubMed⌕ Search

Biomedical subjects

S Kazama

Publications and source records attributed to S Kazama.

At least 73 records · Page 4Linked to original sources
PubMed1980

Malfunction of a Björk-Shiley mitral valve prosthesis due to excessive platelet-fibrin deposition on its sewing cuff. A case report.

A Bjork-Shiley mitral valve prosthesis had to be replaced 4 years after implantation because of disc entrapment by an over-grown fibrous tissue on its sewing cuff. This abnormal fibrous tissue was found out to be an organizing platelet-fibrin deposit, of which luminal surface was only incompletely endothelialized. It is indicated that the heart valve prosthesis generally remains non-endothelialized for a prolonged period of time after implantation in man. Anticoagulation therapy should thus be given throughout the postoperative period for patients with the heart valve prosthesis.

Adult↗
PubMed1979

Lung cancer involving the superior vena cava: pneumonectomy with concomitant partial resection of superior vena cava.

We report two cases in which partial resection and reconstruction of the superior vena cava (SVC) were performed with the use of a temporary SVC-right atrial internal bypass for complete resection of carcinoma of the right lung. In the first case, the SVC was invaded by the primary tumor itself, arising in the anterior segment of the right upper lobe. In the second case a metastasized tracheobronchial lymph node had invaded the SVC. In both cases, partial resection of SVC was performed safely with the internal bypass technique.

Adult↗
PubMed1975

Changes in pepsinogen isozymes in stomach carcinogenesis induced in rats by N-methyl-N'-nitro-N-nitrosoguanidine.

Changes in the isozymes of pepsinogen (Pg) separated from the glandular stomachs of rats were studied by polyacrylamide gel electrophoresis during carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), from the beginning of MNNG administration to 3 months after the end of its 7-month regimen. In 13 of 25 rats killed successively, one (Pg 1) of the three pepsinogen isozymes (Pg 1, 3, 4) normally present in the pyloric mucosa had decreased or disappeared. It decreas was observed from 1 week after the beginning of MNNG treatment to at least 3 months after the end of the 7-month MNNG administration. Remarkable histopathologic changes were found from 8 months after MNNG was given, and rats showing such unusual histopathologic alterations also had changes in their pepsinogen isozyme pattern. In 4 of 27 rats, two (Pg 1, 2) of the four isozymes of pepsinogen (Pg 1-4) in the fundic mucosa decreased or disappeared from 3 months after the beginning of MNNG treatment to at least 2 months after the end of its 7-month administration. Histopathologic changes induced by MNNG were not as remarkable in the fundic mucosa as in the pyloric mucosa.

Adenocarcinoma↗