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Biomedical subjects

S Katz

Publications and source records attributed to S Katz.

At least 649 records · Page 36Linked to original sources

Enhancement of the antiplaque value of antibacterial agents through enamel-conditioning methods: II. Acquisition of antiplaque properties by treated enamel.

Enamel specimens treated with systems containing enamel conditioners and antibacterial agents have previously been shown to incorporate the latter into the enamel. It has now been demonstrated that enamel blocks treated with these systems become highly resistant to bacterial colonization, that this effect is rather long lasting, and that the treated specimens prevent acid formation when incubated with Streptococcus mutans in a sugar-containing medium.

Anti-Infective Agents, Local↗

Enhancement of the antiplaque value of antibacterial agents by enamel conditioning methods: III. Animal results.

A 1:1 water-paste slurry of a placebo and several experimental dentifrices was swabbed daily for six weeks on the teeth of albino rats, and the plaque collected on the teeth was measured in vivo first before the treatments began and one, two, three, and six weeks after. The results indicate that adding a suitable antimicrobial agent to a placebo dentifrice markedly reduced plaque accumulations on the teeth brushed with that product. When an enamel-conditioning vehicle was used instead of the placebo, the antiplaque effectiveness increased severalfold. It was concluded from the two first articles of this series 1,2 that adding antibacterial agents to enamel-conditioning systems resulted in the incorporation of the antimicrobial compound into enamel treated with these systems, and that enamel treated in such a fashion acquired marked antibacterial properties of its own. The data reported in this article support a third conclusion, namely, that the enamel-conditioning-antibacterial systems have a considerable antiplaque effect in laboratory rats.

Animals↗

Parenteral nutrition-induced anaphylaxis.

A case report of a 4-yr-old child who developed an anaphylactic reaction to parenteral nutrition is presented. Dermal allergy tests demonstrated a sensitivity to Travasol solution and Armour multivitamin 2 solution. This is the first reported case known to us of such a response to elemental parenteral nutrition.

Amino Acids↗

Early intervention programme for infants with Down's syndrome.

This article describes an early intervention programme for infants with Down's syndrome (DS) implemented by a registered nurse. The purpose of this programme was to help the families cope with the realities of raising a child with DS and help the infant fulfil his/her maximum potential. Small groups of three-four families with their infants met weekly with the nurse for 2-hour sessions. Each session was divided into two parts: exercises and discussion of issues relating to DS. Implications for nursing practice, education and management are discussed.

Down Syndrome↗

A comprehensive theoretical model of psychological reaction to loss.

This article describes a multidimensional model which may be applicable to study three types of loss, interpersonal loss, loss of a limb or function, and environmental loss or loss of peace of mind. It is a preliminary attempt to collate relevant variables associated with the three types of loss into one comprehensive model which assumes that the dynamic processes associated with and encountered in one area of loss can be extrapolated for use in comprehending other areas of loss. A number of testable hypotheses can be derived for future validation and research.

Culture↗

Phagocytotic activity of monocytes from diabetic patients.

The phagocytotic activity of monocytes from diabetic patients and healthy controls was studied. It was found that the number of phagocytizing cells from diabetic patients was significantly reduced in comparison with that from control individuals. However, the number of bacteria phagocytized per cell was similar in both groups. Plasma from healthy controls added to diabetic monocytes did not cause any significant change in their phagocytotic capacity. Addition of insulin to the plasma of diabetic patients failed to alter the number of phagocytizing diabetic monocytes. Similarly, addition of glucose to control plasma did not affect the number of control monocytes capable of phagocytosis. Protein synthesis was increased during phagocytosis in both control and diabetic cells. The importance of monocytes in the defense mechanism of the organism is discussed.

Adult↗

Treatment of the obstructive nose by CO2-laser reduction of the inferior turbinates: technique and results.

In our department we treat chronically enlarged inferior turbinates (not responding to adequate medical therapy) with the CO2-laser or by partial inferior turbinoplasty. In this work the technique is described and short- and long-term results are evaluated. We divided our study group into two populations: one group with a follow-up of 18 months for which we could obtain objective measurements of the nasal patency by means of a preoperative and postoperative active anterior rhinomanometry, and another group with a follow-up of more than 15 years, for which (because of the absence of a pre-operative rhinomanometry) we could only obtain a subjective evaluation of the results by means of a questionnaire. Relief of nasal obstruction was reported by 88.5% of the patients until 5 years after laser surgery on the inferior turbinates. There seems to be no functional impairment on the nasal mucosa after this kind of surgery. The advantages and drawbacks of this technique are discussed.

Adolescent↗

Long-term efficacy of our surgical approach to turbinate hypertrophy.

In our department, chronically enlarged inferior turbinates (not responding to adequate medical therapy) are treated with the CO2-laser or by partial inferior turbinoplasty. In this work, the latter technique is described and the short- and long-term results (up to 9 years of follow-up) are evaluated. Relief of nasal obstruction was reported by 93.5% of the patients. There was a good correlation between this success rate and the objective measurements of the nasal resistance by active anterior rhinomanometry. Rhinorrhea or postnasal drip was still present in 32.5%. Atrophic changes of the nasal mucosa were not observed in any of the patients. Early postoperative epistaxis was found in 6.5% of the patients. Late postoperative epistaxis did not occur.

Adolescent↗

Impact of traumatic brain damage on family dynamics and functioning: a review.

The purpose of this paper is to review the dynamics and functioning of families with a severely head-injured member. In order to stress the unique problems faced by persons with brain damage and their families, a comparison with spinal cord-injured persons is presented. The review's major conclusion is that a head injury exposes the family to a complex of problems that are unique to this disability and, therefore, necessitates the delivery of special family support services focused on the family, rather than on the head-injured person.

Brain Injuries↗

Impact of traumatic brain damage on family dynamics and functioning: a review.

The purpose of this paper is to review the dynamics and functioning of families with a severely head-injured member. In order to stress the unique problems faced by persons with brain damage and their families, a comparison with spinal cord-injured individuals is presented. The review's major conclusion is that a head injury exposes the family to a complex of problems that are unique to this disability and, therefore, necessitates the delivery of special family support services focused on the family, rather than on the head-injured person.

Adaptation, Psychological↗

Integrating ongoing evaluation process for international pediatric nursing courses.

Two international pediatric courses for nurses from developing countries were planned and implemented in Israel during the past 2 years. The courses consisted of 53 RNs from 29 countries. The purpose of this article is to describe the ongoing evaluation and follow-up process of these courses. Findings indicated that the majority of nurses expressed: a) high satisfaction with the course and felt it enhanced their professional capacity and practice, and benefited their colleagues and superiors; b) high motivation and enthusiasm to improve nursing practices in their home countries; c) changes in attitudes and beliefs relating to pediatric nursing.

Adult↗

Hypercholesterolemia in long-term survivors of heart transplantation: an early marker of accelerated coronary artery disease.

Coronary artery disease remains a significant long-term problem for survival after heart transplantation. Hyperlipidemia is a known risk factor for coronary artery disease in the general population, but the role of hyperlipidemia in cardiac allograft recipients has not been elucidated. To study this problem, we retrospectively reviewed 38 heart transplant recipients who survived more than 3 years after surgery and looked at age, development of diabetes, drug protocol, and development of hypercholesterolemia for a possible correlative or predictive value to the development of early coronary artery disease after heart transplantation. Eleven patients were identified as having coronary disease by the third year after transplantation. High-risk cholesterol values (in milligrams per deciliter) at 6 months after heart transplantation were defined as follows: for ages 10 to 20, 190; 20 to 30, 220; 30 to 40, 240; 40+, 260. We found a strong predictive value with high-risk lipid profiles (p less than 0.01) for the development of coronary artery disease by the third year. No significance was found for a low-risk value, the development of diabetes, or hypertension. All patients below the age of 20 years had coronary artery disease by the third year after transplantation. We conclude that a high-risk cholesterol value at 6 months after transplantation is a strong predictor for development of accelerated coronary artery disease and early graft failure. This has major implications for management of hyperlipidemia in the cardiac allograft recipient.

Adult↗

Use of a soft catheter for acute peritoneal dialysis in infants and children.

Acute peritoneal dialysis in 49 infants and children is described comparing the use of the conventional hard Trocath catheter and the soft catheter. The mean age of the patients was 3.6 years (range 1 day--17 years). Sixteen were treated using the hard Trocath catheter and 33 were treated using a soft catheter. Overall mortality for the total patient population was 43%. Twenty-three neonates were included in the series with an overall mortality of 61%. Significantly less mortality was observed in the 26 patients older than two months of age (31%). Major complications of the dialysis procedure included viscus perforation in three neonatal patients and subcutaneous extravasation of dialysate in two older patients. These major complications occurred only with the use of the Trocath. Two episodes of peritonitis occurred in two adolescent patients and were associated with an interruption of the sterile system. Peritonitis was not specifically related to the type of catheter used. We conclude that major complications associated with the use of the hard catheter for peritoneal dialysis in neonates precludes its continued use in this population. The alternative use of a soft catheter is recommended in neonates. Elective use of a soft catheter for acute peritoneal dialysis in older patients would also seem to be indicated.

Abdominal Injuries↗

The use of patch angioplasty to alter the incidence of carotid restenosis following thromboendarterectomy.

Eighty-nine consecutive patients were followed for twelve to twenty-four months after carotid thromboendarterectomy. Forty-seven underwent operations using a standard carotid closure; a second group of forty-two patients had a saphenous vein patch graft applied in closure. The patients were evaluated with carotid duplex scans at regular intervals to evaluate the incidence of early restenosis. Patients with positive duplex scans underwent arterial angiography or digital subtraction angiography. Operative mortality was zero. Twelve late deaths occurred; eleven due to cardiac disease. In the unpatched group, 19.1% of the patients developed significant restenosis (a luminal narrowing of greater than 50%) with only a 2.4% incidence occurring in the patched group, a statistically significant difference (p less that 0.05). There was a higher incidence of symptomatic restenosis in the unpatched group, though the results were not considered significant. Venous patch rupture was seen in three patients who have not been included in the study group. All of these had venous patches harvested from a distal greater saphenous vein site at the ankle. The authors recommend venous patch closure with a thicker patch taken from the proximal saphenous vein at the groin to reduce the incidence of early restenosis and to avoid venous patch rupture. Regular non-invasive evaluation is recommended to detect restenosis with careful clinical follow-up to evaluate neurologic complications.

Aged↗