Search PubMed⌕ Search

Biomedical subjects

S Katagiri

Publications and source records attributed to S Katagiri.

At least 91 records · Page 5Linked to original sources
PubMed1989

[Evaluation of CT images in pulmonary tuberculosis].

Characteristics of CT images of 40 patients with pulmonary tuberculosis were compared with those of chest radiograms of the same patients, and the clinical usefulness of CT was evaluated. CT findings in pulmonary tuberculosis could be classified as follows. (1) centrilobular shadow, (2) lobular shadow, (3) multilobular shadow, (4) small nodular shadow, (5) pneumonic shadow, (6) cavitary shadow, (7) shadow showing, broncho-vascular dilatation. It was concluded that CT could express far more precisely the location, extension and stage of the tuberculous lesions and could give more informations on the clinical and pathological natures of the lesions than ordinary chest radiograms. Further, CT was superior for the radiological analysis of the detail of the lesions and their distributions.

Adolescent↗
PubMed1989

[Pathology of the idiopathic interstitial pneumonia and diffuse pan-bronchiolitis].

Concept, clinical feature, pathological feature and differential diagnosis of idiopathic interstitial pneumonia and diffuse pan-bronchiolitis are discussed. Author expressed characteristic pathologic feature, but non-specificity of IIP. Diffuse pan-bronchiolitis shows very characteristic pathologic feature and seems to be specific. Accordingly X-ray findings are also characteristic. Early diagnosis is essential for treatment.

Bronchiolitis↗
PubMed1988

Plasma cell leukaemia of non-producer type with missing light chain gene rearrangement.

A case of plasma cell leukaemia of non-producer type is described. The patient presented with typical clinical features of plasma cell myeloma, including multiple osteolytic lesions, hypercalcaemia, renal failure and reduced polyclonal immunoglobulins, except that M-component was not detected in either the serum or urine. Morphological examinations showed a plasmacytoid appearance of the neoplastic cells, while immunological studies failed to detect cytoplasmic immunoglobulin or secretory capacity. The surface phenotype of CD38+, PCA-1+, DR-, CD20-, CD24-, CD9-, CD10- and surface immunoglobulin- was compatible with mature plasma cells. Chromosomal analysis showed the 14q+ marker due to translocation (6;14) and deletion of the short arm of chromosome 1. Analysis of immunoglobulin genes revealed the presence of heavy chain gene rearrangement, but the light chain genes, both kappa and lambda, remained in germline configuration. Such defective immunoglobulin gene rearrangement may be responsible for the failure of immunoglobulin biosynthesis and secretion by the neoplastic plasma cells. Furthermore, it is suggested that the morphological and phenotypic development of B cells may not necessarily depend on immunoglobulin light chain gene rearrangement, and that the oncogenic event in myeloma may occur at an earlier stage of B cell differentiation.

Chromosome Aberrations↗
PubMed1988

[Experimental study on lipid metabolism after partial hepatectomy--with reference to mitochondrial function of the regenerating liver].

Lipid metabolism after hepatectomy was studied in normal rats and cirrhotic rats induced with injections of thioacetamide. In normal rats, the fat accumulation in regenerating livers was observed, which had a maximal peak at 24 hours after hepatectomy. It could be a result of mobilization of fatty acids from fat tissue accompanied with hyperglucagonemia after hepatectomy. Mitochondrial respiration in regenerating liver increased remarkably. Especially when palmitoylcarnitine was used as a substrate, both the respiratory index and ATP synthesis were high until 72 hours after hepatectomy. Mitochondrial carnitine palmitoyltransferase activity was also high. The increase of mitochondrial respiration with palmitoylcarnitine as a substrate was also observed in cirrhotic liver until 72 hours after hepatectomy. These results suggest that mobilization of fatty acids increases after hepatectomy and regenerating liver utilizes fatty acids as a main substrate for hepatic regeneration.

Animals↗
PubMed1987

Immunologic and immunohistologic analysis of 27 cases with thyroid lymphomas.

Twenty-seven patients with stages I or II thyroid lymphomas were investigated immunologically. Approximately 60% of these patients had a goiter for longer than 1 year. Both the tests for serum antithyroid antibodies and histologic findings of the resected specimens showed that chronic lymphocytic (autoimmune) thyroiditis was usually present. The tumors were classified histologically as seven cases of follicular lymphomas and 20 cases of diffuse lymphomas. Immunocytologic study on suspended cells and immunohistologic study on frozen tissue sections showed that neoplastic cells in 22 of 27 cases expressed restricted immunoglobulin light chains. In remaining five cases, the neoplastic cells reacted with B-1, Leu-10, and/or Leu-14. These results indicate that thyroid lymphomas are exclusively B-cell-derived tumors.

Adult↗
PubMed1987

Acute promyelocytic leukemia with an intracerebral mass and meningeal involvement after treatment of non-Hodgkin's lymphoma.

After a 3-month leukopenic phase, a patient developed hematologic pictures of acute promyelocytic leukemia (APL). Treatment with chemotherapy and radiotherapy had been given 10 months previously for a non-Hodgkin's lymphoma (NHL) of diffuse large cell type arising in the Waldeyer's ring. A computed tomographic scan demonstrated a high density mass in the left frontal cerebrum, which was enhanced uniformly by the contrast material. Cytocentrifuge examination of cerebrospinal fluid also showed an excess of promyelocytes. From these observations, the mass was considered to be an infiltration of leukemic cells. The intracerebral mass and meningeal involvement were resolved concomitantly with a hematologic remission of APL after intrathecal injection of cytosine arabinoside and systemic combination chemotherapy. This is a particular case of APL previously undescribed, representing an unusual presentation with intracerebral APL mass as well as a rare posttherapeutic APL following NHL.

Adult↗
PubMed1987

Application of computed tomography for diagnosis of alveolar bony defects.

This study was performed to evaluate the usefulness of computed tomography (CT) in analyzing the three-dimensional structure of alveolar bony defects. The result showed that differences between CT film and actual readings from the cusp ridge to the bone crest were negligible, and the reading on CT film was underestimated approximately 1 mm at the distance from the cusp ridge to the bottom of the bony defect. By reading a series of CT films, one can easily evaluate the type of bony defects. Therefore, application of CT maybe useful for analyzing three-dimensional structure and diagnosis of the alveolar bony defects.

Adult↗
PubMed1987

Follow-up study of type C influenza outbreak in a children's home.

A follow-up study of type C influenza in a children's home was made where the first outbreak of type C influenza occurred in March, 1981. During the survey period of 2 years, 2 additional outbreaks occurred in April and October, 1982 and 4 cases of the secondary and 2 cases of the tertiary infections were serologically confirmed. All of the children exposed to the outbreaks, except 2 particular cases who were suffering from German measles, showed similar mild respiratory symptoms characterized by fever and long-lasting nasal discharge, irrespective of primary, secondary, and tertiary infections. No case of inapparent infection was observed. Incubation period was estimated to be not longer than 5 days and the period of virus shedding, to be longer than 22 days. Antibody response in the sera of patients to type C influenza virus was equally good after every infection, although it was not efficient to prevent the succeeding infection. Factors involved in the repeated infections of type C influenza were discussed.

Adult↗
PubMed1987

Increased circulating Ia-positive T cells in patients with idiopathic thrombocytopenic purpura.

Peripheral blood T cells from 40 patients with idiopathic thrombocytopenic purpura (ITP) were analysed for the presence of surface Ia antigens using monoclonal antibodies by indirect immunofluorescence. The percentage of Ia-positive (Ia+) T cells was significantly increased in patients with ITP (6.8 +/- 2.9%, P less than 0.005) as compared with normal controls (2.3 +/- 0.9%). There was an inverse correlation between the percentages of Ia+ T cells and platelet counts (r = 0.58, P less than 0.005) and a positive correlation between the percentage of these cells and platelet-associated IgG (PAIgG) values (r = 0.55, P less than 0.01). The percentage of Ia+ T cells was found to decrease within two weeks during therapy with high dose gamma-globulin or corticosteroid. We have previously reported the presence of T cells bearing both helper/inducer (H/I) and suppressor/cytotoxic (S/C) phenotypes (double labelled cells, DLC) in patients with ITP and an inverse correlation between the percentages of DLC and their platelet counts. In the present study, we showed that a major part of Ia+ T cells had both H/I and S/C phenotypes. We also examined the correlation between Ia+ T cells and autologous mixed lymphocyte reaction (AMLR). A defective AMLR was demonstrated in patients with ITP. Furthermore, an inverse correlation was found between the percentages of Ia+ T cells and the proliferative responses to AMLR (r = -0.49, P less than 0.01). These results suggest that increased circulating Ia+ T cells play a role in the abnormalities of the immunoregulatory system of ITP, especially in the regulation of autoantibody production.

Antibodies, Monoclonal↗
PubMed1986

Intermediate lymphocytic lymphoma of the thyroid. An immunologic and immunohistologic study.

Four cases of thyroid lymphomas are presented showing curious histologic difficult to distinguish from severe lymphocytic thyroiditis by routine histologic study alone. The age of the patients ranged from 39 to 63 years. Three female patients suffered from autoimmune (lymphocytic) thyroiditis for 2 to 20 years until the present illness. A male patient had no history of thyroiditis. Rapid growth of struma in these patients suggested an evolution of malignant lymphomas. Histologic study results showed that small atypical lymphoid cells with slightly irregular and indented nuclear contour surrounded randomly distributed secondary follicles as a wide mantle. Immunohistologic staining showed that these atypical small lymphoid cells expressed surface properties intermediate between mantle-zone lymphocytes and germinal center cells with a restricted expression of kappa chain in three cases. Stages of tumors were stage I in three cases and stage II in one case. The findings demonstrated were intermediate lymphocytic lymphomas of the thyroid.

Antibodies, Monoclonal↗