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Biomedical subjects

S Kamei

Publications and source records attributed to S Kamei.

At least 109 records · Page 6Linked to original sources
PubMed1989

[A family of pseudocholinesterase deficiency (silent type II)].

We report here a case of pseudocholinesterase (E.C. 3.1.1.8) deficiency, silent type II. The proband was a 29-year-old healthy man. His parents were cousins. A family study revealed that 9 out of 17 members of family investigated (paternal side 6, maternal side 3) concentrations. Serum cholinesterase activity were correlated well with serum albumin concentrations in both healthy people and patients with chronic liver diseases. The ratio of cholinesterase activity to albumin concentrations in serum was found more useful to detect heterozygous pseudocholinesterase deficiency than the serum cholinesterase activity alone. Both the dibucaine number and the fluoride number were within normal range in all family who showed low cholinesterase activity in serum. The amount of immunoreactive substance in serum against anticholinesterase antibody was normal in the proband as well as his family, while it was about twice of the value expected from their activity in those who had low ratio of serum cholinesterase activity to albumin concentrations. These results altogether suggested that the proband was a case of homozygous pseudocholinesterase deficiency, silent type II.

Adult↗
PubMed1989

Heart rate and metabolic responses to participation in golf.

Five healthy middle-aged men were asked to perform 18 holes of golf. Heart rate was measured throughout the play, and blood samples were compared before and after play. Oxygen uptake during play was estimated from their heart rate response during a treadmill-walking test. Mean heart rate was 108 (range 92-121) beats/min, which corresponded to 38 (range 35-41) %VO2max. Caloric cost of golf is 4-6 kcal/min and total energy expenditure was estimated more than 960 kcal during 18 holes. Blood glucose decreased and FFA increased following 18 holes of play. Golfing seems to be a suitable sport for middle-aged and elderly persons to enhance energy expenditure.

Adult↗
PubMed1989

[Cerebrospinal fluid findings in 108 Japanese cases of herpes simplex encephalitis].

Cerebrospinal fluid (CSF) findings were evaluated in 108 Japanese cases of herpes simplex encephalitis (HSE). The diagnosis was based on clinical, neurodiagnostic and serological examinations. The maximum abnormal values for opening pressure, red blood cell number, total protein concentration, white blood cell number and percentage of polymorphonuclear cell recorded in each case throughout the course of the illness were distributed widely in the range of 80 to 450 mm CSF, 0 to 20,700/cu mm, 15 to 1,390 mg/dl, 0 to 1,089/cu mm and 0 to 85%, respectively. Xanthochromia was revealed in CSF in 30 out of 101 HSE cases (30%), in 21 of which the xanthochromia was independent of traumatic bleeding during the punctures. The frequency of high density lesion in brain computed X-ray tomography was 43% (9 out of 21) in patients with xanthochromia. On the other hand, it was only 7% (7 out of 71) in patients without xanthochromia. This difference was statistically significant (p less than 0.01). The main cause for xanthochromia was considered to be an escape of red blood cell from the hemorrhagic necrotizing lesion to CSF in 14% of cases, the elevation of protein in CSF in 9% and both in 29%. Red blood cell was revealed in CSF in 24 out of 61 HSE cases (40%). The number of cases with more than 51 red blood cells/cu mm was 5 out of 10 patients with xanthochromia compared with only 8 out of 50 without xanthochromia. This difference was statistically significant (p less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Cerebrospinal Fluid↗
PubMed1988

Clinical usefulness of an enzymatic determination of total urinary polyamines, excluding cadaverine.

In one widely used enzymatic method for urinary polyamines, the total concentrations of four polyamines--putrescine, spermidine, spermine, and cadaverine--are determined. We report here a simple enzymatic method for measuring the total concentrations of urinary polyamines except cadaverine. The coefficients of variation (CV) for within-run measurements by this method were 4.3% (means = 17.2 mumol/L) and 1.5% (means = 66.5 mumol/L), between-run CVs were 4.8% (means = 16.8 mumol/L) and 1.8% (means = 67.5 mumol/L). The central 95% normal reference interval was 12.3-29.1 mumol/g creatinine for men and 14.1-36.8 mumol/g creatinine for women. In some cases, physiological variations in urinary polyamine excretion were large, mainly because of variations in cadaverine excretion, even in health. Pathological changes in polyamine production in the body may therefore be more easily shown by the excretion of total polyamines excluding cadaverine than by that including cadaverine.

Adult↗
PubMed1987

Serum constituents and liver photomicrographs of wild Suncus murinus in the south of Taiwan.

Serum constituents and liver of the wild male suncus as well as of those bred and fed in our laboratory were examined serologically and histologically. The following results were obtained: The serum glutamic-oxaloacetic transaminase, gamma-glutamyl transaminase, inorganic phosphate, blood urea nitrogen, creatinine, uric acid, and zinc turbidity test levels of wild suncus were higher than those of 4 and 8 week old fed suncus. The total cholesterol level of wild suncus was lower than those of 4 and 8 week old fed suncus. In wild suncus, the total bilirubin and direct bilirubin levels were higher, and the Ca and albumin levels were lower than those of 4 week old fed suncus. However, no significant differences were observed between the wild and the 8 week old fed suncus. Although the alkaline phosphatese and thymol turbidity test levels of wild suncus were larger than those of 8 week old fed suncus, no significant differences were observed between the wild and the 4 week old fed suncus. The histological study revealed the presence of fatty droplets in only 2 of the 67 wild suncus examined while fatty droplets (grade +) were observed in almost all the fed suncus. In one case of the wild suncus, moderate round cell infiltration in interlobular connective tissue was found.

Animals↗
PubMed1986

Serum constituents of Suncus murinus.

Blood samples were collected by cardiac puncture from nine-week-old suncus, mice and rats those had been fasted for 16 hours, and the serum was assayed for the levels of corticosterone, cortisol, and other constituents. The following results were obtained: The serum levels of corticosterone and cortisol and corticosterone/cortisol ratio of suncus were about the same as those of human. The SGPT, gamma-GT, ALP, LDH, Ca and K values in suncus were all within the normal range of the respective values in human. SGOT, amylase, BUN, Na, Cl, Fe and inorganic phosphate values were higher, and total cholesterol, triglyceride, phospholipid, creatinine, urea, total protein, albumin and bilirubin levels were lower in suncus than the respective normal values in human. The values of SGOT, amylase, ZTT, and K were higher in female than in male suncus, while the values of gamma-GT and ALP were higher in the male. Feeding the animals individually in the individual cages for a week increased the values of direct bilirubin, total cholesterol, ZTT, Na, K and Cl and lowered the value of urea. The values of SGPT, ALP and triglyceride of suncus obtained in 1984 were higher, the value of albumin was lower, than the respective values obtained in 1983. The value of cholinesterase in suncus was very small.

Alanine Transaminase↗
PubMed1986

Urinary protein as measured with a pyrogallol red-molybdate complex, manually and in a Hitachi 726 automated analyzer.

In this new method for determining urinary protein, the reaction is complete within 10 min at 37 degrees C. This method is applicable to automated as well as manual measurements. Protein concentration and absorbance at 600 nm are linearly related throughout a wide range of concentrations, 10 to 16 000 mg/L. However, the chromogenicity of the gamma-globulins in this method is 70% of that of albumin, as estimated from results by a biuret method. Within-run CVs were less than 3.3%; the day-to-day CV was 2.9%. Errors due to interfering components in urine are less than 2%. The normal range for urinary protein as measured by this method was from 28 to 141 mg/day. Results by this method (y) and by a trichloroacetic acid-biuret method (x) correlated well (n = 80, r = 0.995; y = 0.99x - 2.9).

Adult↗