From hospital to home: a teaching and learning strategy.
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Community Health Nursing↗
Biomedical subjects
S K Thompson
Publications and source records attributed to S K Thompson.
Introduction to wavelet-based compression of medical images.
Medical image compression can significantly enhance the performance of picture archiving and communication systems and may be considered an enabling technology for telemedicine. The wavelet transform is a powerful mathematical tool with many unique qualities that are useful for image compression and processing applications. Although wavelet concepts can be traced back to 1910, the mathematics of wavelets have only recently been formalized. By exploiting spatial and spectral information redundancy in images, wavelet-based methods offer significantly better results for compressing medical images than do compression algorithms based on Fourier methods, such as the discrete cosine transform used by the Joint Photographic Experts Group. Furthermore, wavelet-based compression does not suffer from blocking artifacts, and the restored image quality is generally superior at higher compression rates.
Humans↗
Atypical glandular cells of undetermined significance on cervical smears. A study with cytohistologic correlation.
OBJECTIVE: The incidence of endocervical adenocarcinoma has increased steadily over the past two decades. Since the Bethesda System was introduced, the diagnosis of atypical glandular cells of undetermined significance (AGUS) has also risen and now accounts for 0.46-1.83% of all cervical (Pap) smears. The purpose of this study was to evaluate the significance of a diagnosis of AGUS using cytohistologic correlation. STUDY DESIGN: A retrospective review of archival material from 1993 through 1996 identified 64 patients who had smears diagnosed as AGUS and had a subsequent surgical biopsy. The smears were reviewed and cytologic features analyzed and correlated with the histologic diagnosis. RESULTS: On biopsy, 3 (5%) of the 64 cases showed endocervical adenocarcinoma in situ (AIS) (1 case with invasive adenocarcinoma also), 14 (22%) had a benign glandular lesion (endocervical polyp, tubal metaplasia, microglandular hyperplasia, reactive changes), 35 (54%) had squamous intraepithelial lesion (SIL) (15 diagnosed on the original smear), and 12 (19%) had no abnormality. Among the cytologic criteria evaluated, feathering (P = .01), palisading (P < .001) and chromatin clearing (P = .002) were shown to have a significant association with the histopathologic diagnosis of AIS/adenocarcinoma. These features were also useful in distinguishing AIS/adenocarcinoma from SIL and benign glandular changes from AIS/adenocarcinoma but not benign/reactive glandular changes from SIL. CONCLUSION: A diagnosis of AGUS correlated with a clinically significant lesion in the majority of cases. Squamous dysplasia (SIL) was the most common lesion identified. The presence of feathering, nuclear palisading and chromatin clearing increased the likelihood of a histologic diagnosis of AIS/adenocarcinoma.
Adenocarcinoma↗