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Biomedical subjects

S K Thompson

Publications and source records attributed to S K Thompson.

At least 37 records · Page 2Linked to original sources

Detectability in conventional and adaptive sampling.

In this paper a simple but very general method is given for estimating a population total with any sampling design when objects in sampled units are observed with imperfect detectability--a problem characteristic of many surveys of natural and human populations. In the most general case, the method consists of dividing the value of the variable of interest associated with each detected object by the detection probability for that object and then proceeding to use the estimation method that would ordinarily be used under the design if there were no detectability problems. Examples illustrating the method include simple random sampling, conventional unequal probability sampling, and adaptive cluster sampling.

Analysis of Variance↗

Radiation-induced changes in the breast: a potential diagnostic pitfall on fine-needle aspiration.

The authors report a case of fine-needle aspiration (FNA) of a breast mass in a 36-year-old woman with previous history of lumpectomy and therapeutic radiation for breast carcinoma. The changes seen were interpreted as recurrent carcinoma, while subsequent biopsy showed only radiation changes. Radiation-induced changes in breast tissue are a potential diagnostic pitfall. The characteristic cytopathologic changes and their differential diagnosis are discussed.

Adult↗

Cytologic diagnosis of a chordoma without physaliforous cells.

Fine-needle aspiration cytology of a presacral chordoma without the classic physaliforous cells is reported. The potential for the misdiagnosis of these lesions when these cells are absent is discussed. The pertinent literature related to this case is reviewed.

Biopsy, Needle↗

Refracture of the patella.

Mildly displaced fractures of the patella, with an intact extensor mechanism, are widely treated in a plaster cylinder. This may lead to disuse osteoporosis of the patella and a subsequent refracture, which may be at a different site. A suggested method of splintage is to use a removable back splint for a period of 1-2 weeks.

Adolescent↗

Cerebral function before and after extra-intracranial carotid bypass.

Thirty-eight patients had their cerebral function measured before and after extra-intracranial carotid bypass surgery using the Halstead-Reitan neuropsychology test battery. Two composite indices of cerebral function for each patient showed them to be impaired before operation. There was no improvement in the composite measures after operation to match that previously demonstrated after carotid endarterectomy. This may reflect the greater pre-operative cerebral impairment of the extra-intracranial group.

Arteriosclerosis↗

Prognosis in infantile idiopathic scoliosis.

A review was performed of 86 cases of infantile idiopathic scoliosis treated between 1962 and 1979. The single primary curves were classified as resolving, stable, progressive with a low rib--vertebra angle difference (RVAD) and progressive with a high RVAD. Two single primary curves subsequently developed a second curve and 17 were double when first diagnosed. Prognosis was difficult to establish before the age of five years. Only 18 per cent of curves showing progression beyond 50 degrees reached that point before the age of four. Conversely, if a scoliosis of 50 degrees or more was present before the age of four it always progressed. A more favourable outcome was indicated by male sex, a left-sided curve, a low initial curve measurement, an RVAD of less than 20 degrees in the initial radiograph, and the onset of scoliosis in the first year of life.

Adolescent↗

Gender-deviant boys compared with normal and clinical control boys.

The physical movement and social characteristics of effeminate behavior-problem, referred boys (N = 13) were compared with those of normal boys (N = 25) and boys (N = 12) referred for nongender problems. Parent reports, observer ratings, and videotapes were collected in a series of structured tasks. As expected, mothers described gender-problem sons as much more feminine than the other two groups in interests, activities, and mannerisms. Gender-problem sons were also seen as relatively inactive and introverted. Further, they were nonsignificantly lower than the clinical control boys in perceived behavior problems, but both groups had marginally more problems than the normal boys. Gender-problem and clinical control boys both showed more body constriction than normal boys in ratings of a videotaped interview. They also both showed less ideal ball-throw form than normal boys on a set of variables scored with slow-motion video. However, in a set of behaviors directly rated in the various tasks, the gender-problem boys gave a uniquely general impression of uncoordination. The groups did not differ on seven additional variables.

Adolescent↗

Anterior cruciate ligament repair for rotatory instability: the Lindemann dynamic muscle-transfer procedure.

The Lindemann operation, originally performed in 1950 as a reconstructive procedure for the anterior cruciate ligament, was performed in the knees of eight patients suffering from rotatory instability. Although the instability persisted, as shown by roentgenographic and clinical examination, treatment with the tendon transfer appears to have provided dynamic stabilization. Seven of the eight patients so treated were subjectively improved, and they returned to sports or activities which they had not been able to perform prior to surgery.

Adult↗

Recognition of verbal labels of pictured objects and events by 17- to 30-month-old infants.

A technique for efficiently presenting a large number of vocabulary items was developed for the testing of vocabulary comprehension in children younger than two years. The technique, incorporating slides of real objects, had the advantages of maintaining the child's attention, motivating task continuation, and overcoming the extraneous contextual cues of test materials. The subjects were 106 children aged 17 to 30 months from a wide range of social status groups, and from both English and Spanish language families. Results indicated significant stability over time as well as a significant relationship to maternal report. Analysis of errors suggested that comprehension develops similarly to production, in that simple nouns were the easiest items, verbs were more difficult, and modifiers and locatives were the most difficult. There were no significant main effects of sex or social status. However, specific environmental variables such as parental attitudes and playmate patterns were significantly correlated with test performance. More flexible family control systems and more interaction with peers were both associated with better vocabulary comprehension in first born children.

Age Factors↗

EEG sleep changes as predictors in depression.

The authors conducted a study of 18 depressed patients to see whether EEG sleep measurements might provide a predictive tool for response to antidepressant medication. They found that although the sedative characteristics of amitriptyline did not differentiate good responders from poor responders until the third week of drug treatment, the good responders showed significant increases in REM latency, decreases in REM sleep time, decreases in REM sleep percent, and decreases in REM activity after only 2 nights of drug treatment.

Amitriptyline↗

Gender labels and early sex role development.

A series of tests was designed for 24-, 30-, and 36-month-old children to measure their ability to apply various gender labels to the appropriate sexes, their capacity to place themselves in their own gender category, and their usage of labels to guide preference behavior. Also, the child's awareness of sex role stereotyping and the relationship of the above measures to parental SES and sex role attitudes were examined. In general, unlike the younger children, the oldest children consistently applied gender labels properly, were certain of their own gender, used same-sex gender labels to guide behavior, and were aware of sex role stereotyping. There was no relation between these measures and demographic variables.

Age Factors↗