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Biomedical subjects

S K Ray

Publications and source records attributed to S K Ray.

At least 73 records · Page 4Linked to original sources

Molecular connectivity and antifungal activity. A quantitative structure-activity relationship study of substituted phenols against skin pathogens.

The plot of minimum inhibitory concentration (MIC) vs. 2Xv of twelve phenolic compounds delineates the congeners into three distinct classes: the most potent ortho compounds describe a parabola, para substituted compounds of intermediate potency lie in a line, while the least potent meta derivatives yield a scatter diagram. The same pattern is found for two skin pathogens, Trichophyton rubrum and Epidermophyton floccosum. From non-linear regression analysis 2Xv is found to be excellently correlated with observed MIC values of the most potent ortho compounds against both the test organisms. For both the organisms logP is found to be inferior to 2Xv in the correlation of MIC values. On the basis of regression equations the MIC values of certain ortho substituted phenols are calculated a priori, some of which are corroborated by findings reported in the literature.

Antifungal Agents↗

Exhumation.

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Adolescent↗

Mathematical models and their applications in medicine and health.

Mathematical models have great potentialities as regards their utility in different disciplines of medicine and health. This paper attempts to elucidate their uses in the field. A brief mention of some models has also been made. Mathematical models are useful in epidemiologic research, planning and evaluation of preventive and control programmes, clinical trials, measurement of health, cost-benefit analysis, diagnosis of patients and in maximizing effectiveness of operations aimed at attaining specified goals within existing resources.

Health Services Research↗

Sentinel surveillance on poliomyelitis and neonatal tetanus: a report.

A 5 year sentinel surveillance (1989-93) of paralytic poliomyelitis and neonatal tetanus was undertaken at a rural Medical College Hospital at Burdwan, West Bengal. Poliomyelitis incidence showed an overall declining trend, which corroborated with the increased OPV coverage over the years. Incidence was more in males than females. Male:female ratio varied between 2.31:1 to 1.2:1. From 1989 to 1992, age-shift in poliomyelitis was observed when more cases were occurring above 1 year subjects. Cases were reported to be high during the months June to September every year. Incidence of neonatal tetanus (NNT) also showed a declining trend during the 5 year study period. A male preponderance was observed. NNT cases were more prevalent during the months between August and November. In an attempt for eradication of paralytic poliomyelitis and elimination of NNT, containment and other public health measures were undertaken a part of surveillance activities. The obstacles encountered in the surveillance system, as well as lacunae identified in undertaking appropriate health measures was discussed.

Age Distribution↗