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Biomedical subjects

S K Carter

Publications and source records attributed to S K Carter.

At least 73 records · Page 4Linked to original sources

Clinical chemotherapy: its correlation with experimental models.

The inputs into clinical trials are many and the possibilities for study are nearly infinite. The only way rational choices and priorities can be established is through the use of experimental models. Clinicians and experimentalists must develop a continuous dialogue so as to mutually develop their questions of importance for study.

Animals↗

Cancer chemotherapy.

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Antineoplastic Agents↗

The chemotherapy of prostatic adenocarcinoma.

A number of chemotherapeutic agents show moderate promise for the palliative treatment of metastatic prostatic carcinoma. Although patterns of metastatic disease make classic response rates difficult to obtain and interpret, doxorubicin, cyclophosphamide, dacarbazine (DTIC), and cisplatin have activity in patients who have failed conventional hormonal treatment. In most studies, a survival advantage is seen for responders to these and other chemotherapeutic agents, but no survival advantage has been seen for the treatment cohorts when compared to groups not receiving chemotherapy. Therefore, estimates of the usefulness of these agents must be considered tentative. Multiple drug therapy has not yet shown definite superiority to single agent treatment. The uses and limitations of acid phosphatase as a tumor marker, as well as particular difficulties in measuring tumor response in the disease, are detailed herein.

Acid Phosphatase↗