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Biomedical subjects

S Ivanov

Publications and source records attributed to S Ivanov.

At least 217 records · Page 12Linked to original sources
PubMed1983

[Circadian changes in gastric acidity during drug therapy of duodenal ulcer].

The circadian change of gastric acidity was studied in 9 patients and 2 controls. Five patients were treated with gastrozepin, two with vicalin and buscolysin, two with biomet according to a schedule. Gastric content was aspirated at fixed intervals and pH determined separately of each portion. The data were juxtaposed to those of the gastric probe prior to the beginning of the treatment. They revealed that with the treatment with gastrozepin and biomet, the lowest pH values during the day were higher, with a statisticall significance, than those obtained at basal conditions prior to the treatment. During the night, pH over 3 was observed only in the treatment with biomet. The methodical conditions used ate suitable both for clinical-pharmacological investigations and for individualization of the treatment of some patients that failed to respond to the ordinary therapeutic combinations.

Adult↗
PubMed1982

[Clinical observations on the therapeutic activity of the preparation mendiaxon in diseases of the biliary tract].

The immediate effect of 400 mg mendiaxon was studied in 8 patients with various hepatobiliary diseases. The drug was administered via a duodenal tube in a duodenal drainage tubing according to a minute schedule during the phase of pure bile C secretion. An increased volume was found in all cases. The maximum choleresis exceeds the basal one from 3 to 8 times. The rate of bile flow, in the majority of the patients, was between 2 and 3.3. ml/min. The treatment was carried out on 25 patients in the course of 10 days with a daily dose of 1200 mg (400 mg three times). A good pain-killing effect was obtained. Adverse effects and allergic reactions were not observed. The results from our studies provided grounds to recommend mendiaxon use in the clinical practice.

Adult↗