Search PubMed⌕ Search

Biomedical subjects

S I Sytnik

Publications and source records attributed to S I Sytnik.

At least 37 records · Page 2Linked to original sources

[Staphylococci in the skin microbiocenosis of the breasts in pregnant women].

The microflora of the mammary glands in the area of the nipple, the areola and the adjacent skin was studied by the methods of washings and impression. 120 nonpregnant women and 164 pregnant women were examined. The pregnant women showed a higher level of the contamination of the above-mentioned sites. The highest density of bacterial population was detected in the area of the nipple and the lowest density, on the skin surrounding the areola. Coagulase-negative staphylococci proved to be the most numerous organisms among all bacterial population found on the skin of the mammary glands of pregnant women. Of these staphylococci, S. epidermidis was most frequently isolated, its isolation rate being higher in the pregnant women than in the nonpregnant ones.

Adolescent↗

[Staphylococci in skin microbiocenosis of the breasts in healthy women].

The autoflora of different anatomical regions of the mammary glands in 120 healthy nulliparous women aged 18-24 years was studied by P. Williamson and A. M. Kligler's methods of smears and washings. From the nipple, the areola, and the adjacent region of the skin 2,248 strains of anaerobic microorganisms were isolated; of these, 63.83% were staphylococci and micrococci, 6.01% were streptococci, 1.91% were Neisseria, 17.79% were Corynebacterium, 3.87% were bacilli, 2.8% were enterobacteria, and 3.79% were fungi. Coagulase-positive staphylococci occurred in 1.56% of cases. Out of 11 coagulase-negative species of this genus, S. epidermidis occurred most frequently on the skin of the mammary glands. The nipple was found to have the highest bacterial contamination (0.55 X 10(6) +/- 0.7 X 10(5) cells/sq. cm for the right mamma and 0.59 X 10(6) +/- 0.7 X 10(5) cells/sq. cm for the left mamma) and the skin adjacent the areola, the lowest bacterial contamination (0.14 X 10(4) +/- 0.2 X 10(3) cells/sq. cm for the right mamma and 0.25 X 10(4) +/- 0.3 X 10(3) cells/sq. cm for the left mamma). P. Williams and A. M. Kligman's method of washings, more accurate and informative, was found to be preferable for the study of the quantitative characteristics of the dermal microbiocenosis of the mammary glands.

Adolescent↗

[Suppression of the adhesive properties of mucosal microflora by ampicillin in peptic ulcer].

Persistence of mucous bacteria in the mucosa of the stomach and duodenum was studied bacteriologically and electron microscopically in 132 patients with peptic ulcer. 235 microbial strains were isolated from the mucosa and its surface in 96 per cent of the patients. 80.8 per cent of the isolates belonged to different species of Staphylococcus and Streptococcus. The other 19.2 per cent of the isolates belonged to 9 rare bacterial species. 235 antibioticograms were analysed and it was shown that the predominating part of the isolates was mainly sensitive to ampicillin. Then follow ampiox, dicloxacillin and benzylpenicillin. Ampicillin was recommended for preoperative sanation of the stomach mucosa. 30 patients were given ampicillin orally in a dose of 0.25 g 4 times a day for 3 days before operations. It was found that the drug inhibited the adhesive properties of the mucous bacteria and even killed them.

Adhesiveness↗

[Antibiotic sensitivity of the bacteria persisting in the gastric and duodenal mucosa of peptic ulcer patients].

Sensitivity of 210 strains of aerobic microbes isolated from the deep layers of the gastric and duodenal mucosa of 80 patients with peptic ulcers was studied with respect to benzylpenicillin, ampicillin, ampiox, methicillin, dicloxacillin, tetracycline, streptomycin, monomycin, neomycin and gentamicin. All strains of 6 streptococcal species, 2 staphylococcal species and pseudodiphtheria bacilli proved to be highly sensitive to ampicillin, ampiox, methicillin and dicloxacillin. Ampicillin had the most pronounced bacteriostatic and bactericidal effects on all cutures, except 7 strains of pseudodiphtheria bacilli. It is recommended to carry out clinical trials of ampicillin with respect to its antimicrobial effect in preoperative sanation of the gastric and duodenal mucosa of patients with peptic ulcers for prevention of postresection gastritis and anastomositis.

Anti-Bacterial Agents↗

[Induced bacterial chemiluminescence].

Oxygen-peroxide-induced superweak luminescence of some microorganisms has been studied by means of the native chemiluminometer KhLM1Ts-01. It is established that total chemiluminescence decrease in the bacteria as follows: Escherichia coli----Bacillus subtilis----Proteus vulgaris----Bacillus mycoides----B. licheniformis----Pseudomonas aeruginosa----Staphylococcus epidermidis----S. aureus----Serratia marcescens----Salmonella enteritidis. A hypothesis is put forward on a possible mechanisms of appearance of the superweak luminescence of bacteria and expediency to use chemoluminometry to differentiate microorganisms.

Bacteria↗

[Antagonistic action of corynebacteria and bacilli of a skin ecotype on staphylococci].

582 strain of corynebacteria and 235 cultures of bacilli isolated from the skin surface of mammary glands of 120 nursing women were studied for their antagonistic action on staphylococci. It is established that bacilli, especially Bacillus subtilis, B. firmus and B. alvei exert more pronounced inhibitory effect on staphylococci. Representatives of the family Corynebacteriaceae possess a weak antagonistic action both on coagulase-positive and on coagulase-negative species. The ability of coryneform bacteria to retain the colonization resistance is supposed to be due to other factors. Antagonistic properties of B. subtilis are shown expedient to be used for elimination of hospital strains of Staphylococcus aureus from the skin of mammary glands.

Actinomycetales↗