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Biomedical subjects

S Horsch

Publications and source records attributed to S Horsch.

At least 91 records · Page 5Linked to original sources

[A recent procedure for intraoperative autotransfusion].

At the surgical unit of the University of Cologne a new system for autotransfusion (Solcotrans) was used in 18 patients. This system consists of a plastic case connected with a vacuum pump by an airtube. After filling the plastic case with 50 ml sodium citrate, 450 ml of blood can be aspirated by the surgeon and be reinfused by the anaesthesiologist. The system was used in shunt-surgery at portal hypertension, at venous thrombectomy and at aneurysms of the aorta abdominalis. Through this, stored blood was not necessary in 13 operations.

Aorta, Abdominal↗

[A new method for intraoperative autotransfusion].

In the surgical department of the University of Cologne a new system for autotransfusion (Solcotrans) was used 74 times in 18 patients. This system consists of a plastic case connected with a vacuum pump by an air tube. After filling the plastic case with 50 ml of sodium citrate, 500 ml blood can be aspirated by the surgeon and reinfused by the anaesthetist. The system was used in venous thrombectomy, in aneurysms of the abdominal aorta and in shunt surgery due to portal hypertension. Thus stored blood was not necessary in 13 operations.

Aortic Aneurysm↗

[Surgery of diseases of the veins (author's transl)].

The article describes the present state of surgery of the v. cava inferior, of the veins of the pelvis and legs in acute phlebothrombosis, post-thrombosis syndrome, traumatic lesions, congenital malformations and in tumour surgery. Every surgical performance concerned with the venous system must be diagnostically clarified by phlebography. The veins of the thigh and pelvis are well visualized by means of ascending phlebography. Closely meshed functional testing by means of phlebography control, as well as venous pressure measurements and peripheral phlebodynamometry are required for timely recognition of an early relapse and for assessing the results of surgery.

Adolescent↗

[Surgical consequences of anomalous arterial blood supply and aneurysms in the epigastric region (authors' translation)].

Abdominal angiography was performed in patients with occlusive disease of the iliofemoral arteries. In 85 of 389 patients, the anomalous arterial blood supply of the upper abdomen was detected accidentally: 81% of the variations were related to the hepatic artery, 19% to the celiac artery. The possible surgical consequences are discussed if these variations are disregarded. Four patients with aneurysms of the visceral arteries (three aneurysms of the hepatic artery, one aneurysm of the superior mesenteric artery) and one patient with a celiac artery compression syndrome were also detected. The latter diseases represent clear indication for operation with high chances of success if treated in time.

Abdomen↗

[Therapy of benign bile duct stenosis (author's transl)].

Simple end-to-end reconstruction of benign bile duct stenosis is possible only in a few cases. To preserve the function of papilla of Vater as the best anticholangitis therapy, we developed a method of bile duct expansion by a pedunculated jejunal patch-graft in animal experiments. After these successful experiments three patients with iatrogenic short bile duct stenosis were treated with this operation. These patients remain free of pathologic clinical and radiological findings 8-30 months after surgery.

Adult↗

[Roentgenographic findings of experimental bowel ischaemia is dogs following occlusion of the superior mesenteric artery (author's transl)].

The results after ligation of the superior mesenteric artery in 17 dogs demonstrated, that a "gasless" abdomen and small bowel pseudo-obstruction are unspecific early roentgenographic findings and bowel-wall thickening with narrowed lumen and increased distance to neighbouring loops are a specific early roentgenographic plain-film findings of acute bowel ischemia following mesenteric vascular occlusion. Approximately 10 hours after ligation a combined distension of small and large bowel with dilatation and air-fluid levels is demonstrable as a sign of paralytic ileus with diffuse peritonitis without possibility of differentiation from other causes of this entity. Gas in the bowel wall, in the superior mesenteric vein and in the portal venous system is a late specific plain-film finding resulting from the invasion of gas-forming bacteria into the devitalized bowel wall with advanced gangrene and a sign of infaust prognosis. The results of the plain-film examinations are correlated to angiographic, clinical and laboratory findings, as well as to histology and bacteriology of the ischemic bowel segments.

Acute Disease↗

[Symptomatology and treatment of malformations of the inferior vena cava (author's transl)].

A review of the embryology, pathophysiology semiotics and surgical treatment of malformations of the inferior vena cava is given based on 3 clinical histories. The cases consisted of a typical membrane occlusion, an atresia of the infrarenal segment and of a hitherto not described combination of several malformations of the inferior vena cava: membrane occlusion, aplasia of the infrarenal segment of the vena cava inferior and multiple aneurysms of the iliac vein. The symptomatology of malformations of the vena cava inferior depends on the compensation by the collateral or the persisting embryonic veins, respectively, and on the localization and the degree of the obliteration. The varying hemodynamic reactions are described. The following surgical methods for the treatment of inferior vena cava occlusions in the hepatic segment are available: The so called conservative interventions for the creation of collaterals, the direct or indirect recanalization and the bypass operation. Congenital infrarenal atresias of the vena cava are corrected by homologous or prosthetic interposition. The venous replacement with a bovine heterograft presented here, has not yet been described in the literature.

Adolescent↗

[Segmental venous replacemnet with heterologous graft (author's transl)].

Results of animal experiments are presented on the applicability in the low pressure system of a collagen prosthesis, which has been used successfully, for considerable time, in the arterial replacement in patients and dogs. Grafts of up to 7 cm in length were implanted into the suprarenal segment of the inferior vena cava (v. cava caudalis) in dogs and observed clinically over a period of more than 500 days. Histological investigations were made. With some limitations the results obtained are considered as good and point towards the applicability of the examined graft material in the low pressure system.

Animals↗

[Bile duct reconstruction with pendunculate jejunal grafts (author's transl)].

A pedunculate patch, obtained from a disconnected segment of jejunum, was implanted into the longitudinal incision of the ductus choledochus. Intra-operatively, the findings were based upon direct cholecystocholangiography; postoperatively, upon laboratory tests. After an observation period of 12 months a new cholangiography of the transplant was made along with a selective picture of the mesenteric arteries. The choledochus duct with the transplant was examined histologically. Three dogs died immediately postoperatively of peritonitis due to suture insufficiency. Five dogs died of invaginate ileus. These animals, as well as the remaining 8 dogs showed macroscopically and microscopically a smooth and uneventful healing of the transplant at the end of the observation period. Radiographies showed free flow of the biliary duct system. The selective mesenteric arteriographies evidenced beginning anastomosis between the transplant and the capillaries of the bile duct. Based on the results presented, the pedunculate jejunal graft can be considered well suited as an expansion graft for the bile duct.

Animals↗

[Replacement of the iliac veins and the infrarenal vena cava regment with heterologous grafts in animal tests (author's transl)].

A bovine collagen graft was implanted in 30 dogs for the replacement of the femoral vein, the iliac vein and the inferior vena cava. During the observation period up to 210 days six thromboses of the graft were observed. Histological results after 30 days: development of a "neo-intima" with collagen type III, originating from the anastomosis. After 90 to 210 days: Continuous endothelial layer of the graft with appearance of smooth muscle fibers in the neo-intima. From the graft bed there was found resorption of the bovine collagen and replacement by new collagen type III fibers.

Animals↗

Replacement of the inferior vena cava and iliac veins with heterologous grafts in animal tests.

The use of a modified bovine collagen graft as a low-pressure conduit was investigated by implantation into the iliocaval system of dogs. In the 210 day observation period, a patency rate of 87.5% was achieved. Nearly all graft failures occured within the first 14 days following implantation; failure after that time did not seem to be dependent upon length of time of implantation. Progressive organization of the neointima was seen histologically. New smooth muscle fibers were observed in the neointima with electron microscopic evidence of reconstitution of the subendothelial membrane. Continuing resorption of graft collagen coincided with its replacement by newly developed collagen type III fibers in a surface-parallel orientation.

Animals↗