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Biomedical subjects

S Horsch

Publications and source records attributed to S Horsch.

At least 73 records · Page 4Linked to original sources

Subclavian steal syndrome in a congenitaly anomalous subclavian artery: a case report.

The case of a 50 year-old man with a subclavian steal syndrome caused by an occlusive lesion of an aberrant right subclavian artery is presented. There was no dysphagia lusoria. The right subclavian artery was anastomosed to the right common carotid artery. At follow-up, 18 months later, the patient is symptom free and the right subclavian artery is patent.

Aortography↗

Intraoperative autotransfusion with a new disposable system.

In the past 2 years we have used a simple, disposable set for intraoperative autotransfusion. The system consists of a rigid plastic case with a flexible bag inside constituting a 600 ml reservoir which can be connected to any suitable vacuum source. We used it so far in 56 patients undergoing various vascular operations who were autotransfused a total of about 160 units of blood without any complications with regard to blood coagulation or hemolysis.

Blood Transfusion, Autologous↗

[Changes in somatosensory evoked potentials in carotid desobliteration. Diagnostic significance and possible consequences for therapy].

The cerebral function of 55 patients with stenosis and occlusion of carotid arteries was monitored intraoperatively by serial examination of somatosensory cortical evoked potentials (SEP). In 40 uncomplicated operations no significant alteration of the SEP was detected. In 13 examination series, however, reversible abnormalities were noted. Furthermore, in two cases irreversible SEP loss was documented. The nature and temporal development of SEP alterations enabled differentiation of possible etiological factors. Bilateral abnormalities were indicative of global hypoxemia whereas acutely arising unilateral SEP loss suggested embolic occlusion of cerebral arteries. Intraoperative SEP monitoring therefore appears to be of diagnostical and differential diagnostical value and allows statements in respect to further intra- and postoperative treatment.

Brain Damage, Chronic↗

[Asymptomatic carcinoid in a Meckel's diverticulum as the incidental finding in the operation of an abdominal aortic aneurysm].

A case report is given of a patient who had surgery because of an aneurysm of the abdominal aorta. During laparotomy a tumor in Meckel's diverticulum was found, which was removed by tangential incision without opening the intestine as to avoid an infection of the prosthesis. The tumor had a diameter of 1.5 cm and histology showed transmural spread of the carcinoid tissue; under these conditions further metastatic spread is possible. After the patient had recovered successfully from aneurysm surgery he was operated again and partial resection of the small intestine including the regional lymphatic system was performed. Carcinoid tissue was found during histological examination in the submucosal layer of the intestine in the area where surgery had been done before; no pathological changes however were found in the mesenterium. Thus the patient can be considered to be cured.

Aorta, Abdominal↗

[Early morbidity and fatality following carotid disobliteration].

At the University Hospital of Cologne-Lindenthal 260 patients underwent carotid endarterectomy during a period of 10 years. 9 patients died, representing an operative mortality rate of 2.9%. 80% of our patients with an acute stroke died. We see no indication for surgery in acute stroke. Postoperatively, 20 patients had a neurologic deficit, transient deficits occurred in 3,6% (11 patients) permanent deficits in 3% (9 patients). Carotid endarterectomy may be complicated by cranial nerve damage. The importance of these injuries is evident if bilateral carotid endarterectomy is being considered.

Carotid Artery Diseases↗

[Blood vessel wall regeneration in the use of a new monofilament, resorbable suture material for arterial anastomoses].

A new synthetic, absorbable suture has been tested on 15 mongrel dogs. A total of 132 simple end-to-end anastomoses has been performed in common carotid, iliac and femoral arteries and the aorta abdominalis with monofilament, absorbable polydioxanon. Aneurysms or infections did not occur. The patency rate up to 250 days was 98.5%. All vessels were studied by angiography and light- or electron-microscopy. The new monofilament suture material is characterized by extended absorption time and low foreign body reaction. It leads more rapidly to the restitution of the vascular wall than nonabsorbable sutures.

Arteries↗

Angiosarcoma in primary lymphedema of the lower extremity--Stewart-Treves syndrome.

After a 20-year latent period an angiosarcoma developed in the edematous leg of a 74-year-old woman with primary lymphedema. A deep venous thrombosis of the leg which further aggravated tissue swelling preceded the appearance of angiosarcoma. Histogenetic classification of the tumor as hemangiosarcoma rather than lymphangiosarcoma was favored by positive immunohistochemical staining for Factor VIII. Despite high amputation and isolated perfusion with hyperthermal cytostatic infusion, she developed local recurrence and distant metastases and died 16 months after operation. Patients with chronic primary or secondary lymphedema are susceptible to angiosarcoma although the overall risk is small.

Aged↗

[Profundaplasty in older persons].

The profunda femoris artery has become the most important collateral vessel for compensating femoro-popliteal arterial occlusion. The circulation of the ischaemic limb can be obtained by profundaplasty. From 1972 to 1982, 70 patients with a mean age of 75,7 years underwent surgery. Good results were obtained in 75,9%.

Aged↗

[Vascular replacement of small caliber arteries--a new bovine collagen prosthesis].

A new bovine collagenic prosthesis (Solcograft P) was tested in animal experiments. In 45 dogs the infrarenal abdominal aorta was substituted. During a follow-up period of up to 18 months the functional rate amounted to 88%. Joint-crossing iliaco-femoral bypasses were implanted in 31 dogs, 5 times in both sides. For the new bovine collagenic graft the functional rate ran up to 83%, during a follow-up period of 9 months. A wound infection was observed twice in the inguinal region thus exacting the removal of the prosthesis. An aneurysm was not observed. In our opinion the satisfying results are due to the compliance of the new prosthesis which is similar to natural artery.

Animals↗

Surgery of the venous system - present state of the art.

The current status of surgery of the inferior vena cava, and the iliac and femoral veins in cases of phlebothrombosis, of postthrombotic syndrome, and in traumatic lesions is discussed. Each intervention in the venous system requires an exact preoperative diagnosis including phlebography and phlebodynamometry. After a mean observation period of 26 months, 41.4% excellent results were obtained following venous thrombectomy in cases of phlebothrombosis. Vena cava blockade as a prophylactic measure against pulmonary embolism is an accepted procedure now. It remains, however, limited to a few exceptional situations. Venous injuries proximal to the elbow and the knee can be successfully treated by direct suture or graft implantation with good functional results, whereas ligature of large veins causes postthrombotic syndrome of the limbs in over 50% of the cases. Chronic occlusion of iliac veins and postthrombotic syndrome may be treated by reconstructive methods, with the aid of a temporary arterio-venous fistula. The prerequisites of patent run-in and run-off reduce the number of operations to but a few cases.

Adult↗

[New nutritional index for preoperative evaluation of malnutrition as a risk factor in surgery].

In a retrospective trial preoperative anthropometric and biochemical dates of 72 cancer patients were measured. All patients underwent a major surgical resection. Discriminant analysis and a computer-based stepwise regression procedure were used to identify the most important variables. It was able to compute a linear predictive model of 7 variables, called Nutritional Index, relating risk of operative mortality to preoperative nutritional status. In a prospective control trial it was possible to confirm the predictive value of the Nutritional Index by nutritional assessment of 204 surgical patients undergoing a major surgical procedure. This Nutritional Index provides a quantitative classification in surgical patients at high, low and without increased risk of nutritionally based complications.

Female↗