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Biomedical subjects

S Holmes

Publications and source records attributed to S Holmes.

At least 163 records · Page 9Linked to original sources

A controlled trial of different treatment regimens in patients with urinary tract infections after lower urinary tract surgery.

One hundred and four patients who developed urinary tract infections after catheterization for acute retention of urine and surgery of the bladder or urethra were randomly allocated to four treatment groups. Analysis of the results in 65 patients showed that co-trimoxazole and 1 g cephradine administered twice daily for 1 week were successful in eradicating the urinary tract infections in 93% and 88% of the patients, respectively. The same dose of cephradine administered 4-times a day eradicated 64% of the infections. In patients for whom no treatment was given, the original infection did not clear in 65%. Escherichia coli and coagulase-negative staphylococci were the commonest infecting organisms. The in vitro sensitivity testing of antibiotics did not correlate well with the successful eradication of the infecting organism.

Aged↗

Pharmacist's impact on chronic psychiatric outpatients in community mental health.

The impact of a specially trained pharmacist upon the treatment of chronic psychiatric outpatients being maintained within their communities was studied. The quantity and costs of the services provided were assessed as well as patient satisfaction and well-being. Three years of management information data from eight mental health centers were used to compare the medication monitoring services provided by pharmacists and psychiatrists. In a separate study of chronic psychiatric outpatients, patients treated exclusively by the pharmacist were compared with patients treated by other mental health professionals on measures of community adjustment and satisfaction with treatment. The pharmacist monitored the medications of about 200 chronic psychiatric patients each month. The cost of a pharmacist providing medication monitoring services was 40% of the cost of providing that service by a psychiatrist. The pharmacist's patients were found to be functioning in the community as well as or better than other patients and their reported satisfaction with treatment was at least that of other chronic psychiatric patients sampled. The psychiatric pharmacist in this study successfully monitored stabilized psychiatric patients within their communities.

Ambulatory Care↗

A gift.

Explore the source record for details and available documents.

Heart Defects, Congenital↗

Panic disorder in hospitalized cancer patients.

Cancer is commonly complicated by psychiatric comorbidity, particularly depression. However, the effects of panic on cancer treatment and cancer patients' quality of life are not well understood. To examine more closely the occurrence of panic attacks and panic disorder in cancer patients, we retrospectively reviewed charts of 106 consecutive psychosomatic consultations of inpatients with cancer at a regional cancer center. Approximately one-fifth of the patient sample presented with panic attacks or panic disorder at the time of the consultation. We present four case examples to demonstrate the potential effect of panic on cancer patients, including requests for cancer treatment discontinuation. We report resolution of panic with benzodiazepine and selective serotonin reuptake inhibitors.

Aged↗

Depression in general practice attenders. "Caseness", natural history and predictors of outcome.

Assessment of 564 routine attenders of 12 Sydney general practices established that 25% of the women and 17% of the men scored as "potential depressives". Thirty-five agreed to an interview and review over 6 months, with 83% of this group initially rating as a "psychiatric case" on the Present State Examination. The sample could be characterized as being chronically depressed (mean duration of 9 months), as predominantly (86%) female, in having relatively stable but dysfunctional relationships, and by having experienced chronic and acute-on-chronic stressors. The degree of which subjects improved in the following 20 weeks could be predicted by their degree of improvement in the first few weeks and as early as the 6th day after assessment. While overall improvement was minimal, several baseline predictors of a better outcome were suggested: a history of having episodic or recurrent episodes, a more severe depression, lower social class, break-up of an intimate relationship as a precipitant, a neutralizing life event and family support. Married subjects and those with young children had a poor outcome.

Adjustment Disorders↗

Blood preservation XXVI, CPD-adenine packed cells: benefits of increasing the glucose.

In searching for the optimal glucose concentration, this lab has monitored ATP, 2,3-DPG, pH, and glucose levels of samples taken from full blood units stored for 6 weeks at 4 C. The blood was collected into CPD-adenine containing 100, 125, 150, 175, and 200 per cent of the glucose present in CPD. The units were stored as whole blood, soft packed (50 to 70% Hct), or hard packed units (80 to 95% Hct). ATP values in general did not decrease very greatly in whole blood units and only moderately in soft packed units. However, in hard packed units a steady progressive decrease in the ATP values was seen to begin at day 14. In these hard-packed units the only improvement with extra glucose was seen beginning at day 14 when ATP maintenance was better with 200 per cent glucose, but the improvement was not significant until day 42. However, at 35 days the ATP values for 200 and 175 per cent glucose were noticeably better than for the other preservatives. Therefore, it appears from this study that the glucose concentration in CPD-adenine for hard-packed cells should be at least 175 per cent of that in regularly formulated CPD. Also, there would appear to be an advantage of having 200 per cent glucose in those units of blood that may be stored beyond 35 days for emergency blood shortage times.

Acid-Base Equilibrium↗

Incoming nursing students' perceptions of their caring behaviors.

What are the caring attitudes and abilities of incoming nursing students? This phenomenologic study used the Colaizzi method to analyze descriptions of caring interactions written by 15 incoming nursing students on orientation day. It indicates that students have definite attitudes and values about caring and established patterns of caring behaviors. Educators need to start where the learners are-namely, recognizing and valuing their inherent caring behaviors. Using these threads, nurse educators can begin to weave the fabric of professional caring.

Adult↗