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Biomedical subjects

S Herman

Publications and source records attributed to S Herman.

At least 91 records · Page 5Linked to original sources
PubMed1987

Computed tomography in advanced ovarian cancer: an evaluation of diagnostic accuracy.

The authors have investigated the diagnostic accuracy of computed tomography (CT) of the abdomen and pelvis in the assessment of patients prior to second-look laparotomy for advanced ovarian cancer. CT studies (read independently by three radiologists) and laparotomy findings were analyzed in 50 patients. Sensitivity varied from 0.30 to 0.65 among the radiologists, specificity from 0.44 to 0.89, positive predictive value from 0.50 to 0.73, and negative predictive value from 0.60 to 0.70. Receiver operator curve analysis of the data indicated poor performance of CT as a diagnostic test. The authors also examined some problems in interpreting their data and that of others in the literature, in particular, the influence of potential sources of bias.

Evaluation Studies as Topic↗
PubMed1986

Computed tomography in advanced ovarian cancer. Inter- and intraobserver reliability.

We have examined the reliability of computed tomography (CT) in the assessment of patients with advanced ovarian cancer. Three radiologists independently read the same set of 140 CT scans. Fifty percent of the films were reread by the same radiologist to assess intraobserver agreement. In addition we assessed variability among radiologists in reporting signs of disease such as a mass and ascites and the variability in reporting a change in signs in response to therapy. Intraobserver agreement on the identification of signs such as a mass and ascites and on overall response to therapy was moderate to excellent (Kappa 0.52-0.84). Agreement among observers on the same signs was not as good (Kappa 0.36-0.79).

Adult↗
PubMed1986

Type As who think they are type Bs: discrepancies between self-ratings and interview ratings of the type A (coronary-prone) behaviour pattern.

The study described here explored discrepancies between self-ratings and interview ratings of Type A behaviour. A total of 281 patients referred for diagnostic coronary angiography underwent a comprehensive psychological assessment including the Type A structured interview (SI), the Minnesota Multiphasic Personality Inventory (MMPI) and two self-report measures of Type A behaviour, the Jenkins Activity Survey (JAS) and the Type A Self-Rating Inventory (TASRI). Two subgroups of patients were identified--Type A subjects whose Type A self-ratings were consistent with the SI classification, and subjects who obtained low self-rating scores and yet were classified as Type A by the SI. A comparison of the MMPI profiles showed that the discordant Type As scored lower on MMPI scales 9 (Ma) and 4 (Pd), and higher on scales 0 (Si), 2 (D) and F. The personality attributes associated with this MMPI pattern are more consistent with individual self-reports of Type A behaviour than observer ratings during the SI.

Coronary Disease↗
PubMed1986

Magnetic resonance imaging of the mediastinum.

Seven normal volunteers and 69 patients with known disease in either the mediastinum or hila or both were imaged using a prototype magnetic resonance imager operating at 0.15T. Normal mediastinal and hilar structures were readily identified and mediastinal diseases were well demonstrated by magnetic resonance imaging (MRI). The value of MRI lies in the morphological demonstration of the presence and extent of disease.

Adult↗
PubMed1985

Development of a brief self-report measure of the type A (coronary prone) behavior pattern.

This study reports the development of a brief self-report measure of the Type A behavior pattern based upon a set of adjectives derived from the Gough Adjective Checklist (ACL). Previous work from our laboratory established a set of adjectives identified by experts as being relevant to the Type A construct that subsequently was found to successfully distinguish Type A individuals from their Type B counterparts. In the present study, a Type A self-rating scale based on these adjectives was found to be significantly related to an established Type A self-report instrument, the Jenkins Activity Survey (JAS), and to an independent behavioral rating based upon a standard structured interview (SI). However, no measure of Type A was related to the severity of coronary artery disease (CAD) as documented by coronary angiography. The advantages and disadvantages of the various Type A measures are discussed in the context of their ability to identify individuals at risk for the development of CAD.

Coronary Disease↗
PubMed1985

Studies of bronchial secretion. The influence of inflammatory response and bacterial infection.

Bronchial secretions obtained during bronchoscopic examination of 60 children suffering from respiratory tract infections were studied for the concentration of immunoglobulins, anti-proteolytic factors, lactoferrin, and lysozyme. Eleven children having bronchial asthma without a history of chronic or recurrent infections of the respiratory tract were designated as a control. The results were analysed in relation to clinical diagnosis (chronic bronchitis, bronchitis, bronchiectasis) or to the local status of bronchial mucosa at the time of bronchoscopy (no inflammation, inflammation, inflammation with documented bacterial infection). The statistical analysis of the results revealed a decrease of lactoferrin and locally produced IgA in the group of children suffering from bronchitis and chronic bronchitis. Samples infected with Haemophilus species had significantly higher concentration of lactoferrin than any other group. Similarly, albumin in this group was higher than in the other group except that other bacteria were present. Samples infected with Haemophilus also had increased concentrations of S-IgA, IgG, and anti-proteolytic factors when compared with the group without local inflammation.

Bacterial Infections↗
PubMed1984

The Même implant.

Eighty-one patients have had breast augmentation with the Même implant since November of 1981. All breasts remain free of spherical capsules or palpable edges. The reason for these good results is still unknown. Although it is too early to determine whether the problem of capsules has been conquered, the results thus far are encouraging.

Breast↗
PubMed1983

Efficacy of computed tomography in the management of cancer patients.

An evaluation was made of 1030 computed tomography (CT) scans performed on cancer patients. Seventy percent of the scans taken were of the pelvis, abdomen, or thorax. Both referring clinicians and radiologists rated the diagnostic and management efficacy of each scan using a simple scale of values. Over 50% of the scans provided unique diagnostic information: 39% resulted in a change in diagnosis or in known extent of disease; and 14% led to a change in patient management. The fraction of abnormal results was not a reliable measure of efficacy. Specific groups of patients were identified, which demonstrated that both diagnostic and management efficacy should be measured in assessing the value of CT as a diagnostic modality.

Brain Neoplasms↗
PubMed1983

[Effects of progressive lengthening on the growth cartilage. Value of measurement of the torque].

The authors have studied the pressures exerted on the growth plate during 35 progressive lengthenings of the tibia. This pressure was assessed by an indirect method. The patients have been followed up for several years. There was a correlation between the pressure and the extent of growth later. The authors consider that this aspect should be carefully considered during the period of lengthening to avoid disturbance of future growth.

Bone Lengthening↗