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Biomedical subjects

S Hasebe

Publications and source records attributed to S Hasebe.

At least 73 records · Page 4Linked to original sources
PubMed1993

Intraoperative suspension-recession technique for treatment of vertical strabismus in thyroid myopathy.

Ten patients underwent extraocular muscle surgery with an intraoperative suspension-recession technique for diplopia induced by vertical strabismus in thyroid myopathy. The average ratio of the reduction of vertical deviation to the amount of surgery was 1.8 degrees/mm (range, 1.0 degrees/mm-2.8 degrees/mm). Eight (80%) patients had single binocular vision restored in the primary position without prism or compensatory torticollis after surgery. One patient who showed evidence of abnormal thyroid function at surgery developed an overcorrection postoperatively.

Adult↗
PubMed1992

Synoptometer analysis of vertical shoot in Duane's retraction syndrome.

Vertical deviation of the affected eye caused by horizontal change of gaze was measured with a synoptometer in 5 cases of Duane's retraction syndrome type III. Step-by-step measurement clearly showed two types of incomitance patterns, i.e. upshoot and up- and downshoot in adduction. The former suggests a paradoxical synergistic innervation between the medial rectus and superior rectus muscles, and the latter suggests an abnormal vertical movement of the lateral rectus muscle over the globe on elevation or depression of the eye. Recession of the lateral rectus muscle, however, reduced the vertical deviation regardless of the incomitance pattern.

Adolescent↗
PubMed1992

Distribution of efferent neurons projecting to the tectum and cerebellum in the rat prepositus hypoglossi nucleus.

Distributions of efferent neurons projecting to the superior colliculus (SC), the pretectum, and the cerebellar cortex were studied in the rat prepositus hypoglossi nucleus (PRH) by retrograde labeling with wheat germ agglutinin-horseradish peroxidase (WGA-HRP). After injection of the tracer into the unilateral SC, small- and medium-sized neurons were labeled throughout the entire rostrocaudal extent of the PRH, with the highest proportion in the middle part of the nucleus. After application of WGA-HRP to the unilateral pretectal region, including the nucleus of the optic tract, numerous labeled neurons appeared in the bilateral PRH. The highest distribution was found in the most rostral part of this nucleus. Furthermore, small neurons of the supragenual nucleus of the facial nerve also were labeled. Injection of WGA-HRP into lobules VI-VII of the cerebellar vermis resulted in the labeling of mainly medium-sized neurons in the bilateral PRH, primarily in the caudal third. WGA-HRP-labeled neurons were less frequently observed in the PRH after unilateral injection into the flocculus and paraflocculus. Retrograde double labeling by fluorescent dyes showed that a few neurons in the middle part of the PRH sent divergent axons to vermal lobules VI-VII and the SC.

Amidines↗
PubMed1992

[Classification of congenital superior oblique palsy based on principal component analysis].

An attempt was to classify unilateral congenital superior oblique palsy principal component analysis. Each principal component was calculated by taking a linear combination of an eigenvector of the correlation matrix with a standardized original variable. The variables selected for the analysis were vertical deviation in the nine diagnostic positions of 51 cases measured by a synoptometer. The cumulative contributive percent of principal components showed that 88.5% of the variation were accounted for by the first three principal components. The first principal component accounted for 56.7% of the variation in samples indicating the extent of superior oblique palsy in which vertical deviation increases or decreases proportionately. The second principal component accounted for 20.6% of the variation of samples indicating the extent of the incomitance of vertical deviation with a vertical change of gaze. The third principal component accounted for 11.1% of the variation in the sample indicating the extent of the vertical deviation with a horizontal change of gaze.

Adolescent↗
PubMed1992

[Evaluation of preoperative prism adaptation in patients with acquired esotropia].

A prospective study was carried out of the evaluation preoperative prism adaptation in 77 patients with acquired esotropia. Sixty-three patients who showed a stable esodeviation with prisms of 10 prism diopter or less by alternate prism cover test and fusion response to the prisms were classified as prism responders and were randomly classified into two groups. Thirty-one patients of prism responders underwent surgery based on the prism adapted angle. Patients in the other 32 cases were assigned to undergo surgery for their initially measured angle. On the other hand, 14 patients who did not respond to prism adaptation underwent surgery for their preoperative measured angle of deviation. Success rates with deviations of 0 to 10 prism diopters measured 1 year after surgery by the alternative prism cover test at 5 m and with fusion on Bagolini's striated glasses test were highest (26 [84%] of 31 patients) in prism adaptation responders who underwent surgery for prism determined angle and lowest (3 [21%] of 14 patients) in the prism adaptation nonresponder who showed no fusion response to the prisms.

Adaptation, Ocular↗
PubMed1992

[Frequency response of ocular counter-rolling analyzed with passive sinusoidal head roll].

Using a computerized motor-driven chair that oscillates the subject's head in the frontal plane and a real-time video processing system for analyzing torsional eye movements, the frequency response of ocular counter-rolling to passive, sinusoidal head rolling was studied in darkness in 3 normal subjects. The gain of counter-rolling increased its mean value from 0.22 (0.17 Hz) to 0.52 (1.33 Hz) along with the frequency of head oscillation. Its phase error with respect to ideal compensation was slight (173-181 deg). Furthermore, the gain of counter-rolling was increased slightly from 0.31 (+/- 5 deg) to 0.39 (+/- 20 deg) along with the amplitude of head oscillation. Our experimental results agreed with the characteristics of the frequency responses for voluntary head shaking previously reported by Collewijn and colleagues, except that counter-rolling had a slightly lower gain.

Adult↗
PubMed1992

[Real-time measurement of torsional eye movements by video-based technique].

The authors developed a real-time measurement system to analyze torsional eye movements using video-based technique with two small dots on a soft contact lens as the targets. The lens, saturated with physiological saline solution, was made to adhere to the eye by dropping distilled water on it, according to Edelman's method. It was demonstrated that the clear image of the lens marker was sufficient to extract torsional eye information without using complex image processing technique and that the lens attached firmly to the eye during recordings. An engineering work station (Hewlett Packard Inc, HP9000/350) was used for hardware implementation, which required only 15 milliseconds to process one frame of a video image and the torsional angle was able to record and display in real-time rate. The accuracy (precision error) of this measurement, evaluated by simultaneous recordings with dyed dots on the conjunctiva and an error propagation analysis, was better than delta = 0.08 degrees.

Contact Lenses↗
PubMed1991

[Advancement of the anterior portion of the superior oblique tendon in case of traumatic bilateral trochlear palsy].

The effect of the advancement of the anterior portion of the superior oblique tendon on cyclovertical and horizontal deviation was studied in seven cases of traumatic bilateral trochlear palsy by using a synoptometer (Cüppers) and cyclodevinometer (Kolling). The anterior portion of the superior oblique tendon was disinserted and advanced laterally according to the amount of the cyclodeviation in primary position with 1 degree/mm. Surgery was done in 5 cases on both eyes, in 2 cases on one eye. The age of the patients ranged from 20 to 64 years (mean 45 years). The excyclodeviation was significantly reduced (p less than .01), however overcorrection was found in the upward gaze. The mean reduction of excyclodeviation in diagnostic positions of gaze was approximately 10-12 degrees. The vertical deviation was significantly reduced in up and downward gaze (p less than .05), nevertheless overcorrection was found in the upward gaze. The mean reduction of the vertical deviation differed according to their positions of gaze. V-pattern esotropia could not be reduced significantly. Therefore an alternative operative approach must be found which can avoid overcorrection in the upward gaze and moreover correct V-pattern esotropia in the downward gaze.

Adult↗
PubMed1990

Anomalous posterior insertion of medial rectus muscle simulating congenital oculomotor palsy.

An unusual case was examined in our Hospital showing severe exotropia with adduction palsy. However, during surgery, anomalous posterior insertion of the medial rectus muscle was found, and the Hummelsheim operation was performed to correct the exotropia. To the best of the authors' knowledge, this is the first report of anomalous posterior insertion of the medial rectus muscle as a cause for congenital exotropia with adduction palsy.

Child↗
PubMed1990

[Measurement of incomitance patterns of vertical deviation in superior oblique palsy with a synoptometer].

By using a synoptometer we tried to compare the incomitance pattern of the vertical deviation in congenital superior oblique palsy with that of the vertical deviation in acquired superior oblique palsy. The data were transformed to a three-dimensional format by a computer to classify the incomitance pattern. With this method we found a difference in the incomitance pattern between congenital and acquired superior oblique palsy. In cases of congenital superior oblique palsy the vertical deviation increased proportionately with the change of gaze from abduction to adduction, since the incomitance caused by the horizontal change of gaze was more marked than that of the vertical change of gaze. However in cases of acquired superior oblique palsy the vertical deviation increased proportionately with change of gaze from up- to downward positions, therefore the incomitance caused by vertical change of gaze was more marked than that of the horizontal change of gaze. Moreover congenital superior oblique palsy was classified into three types according to the classification of Wieser and their incomitance patterns of vertical deviation were compared with each other.

Adolescent↗
PubMed1990

[Surgical effect on incomitance of vertical deviation in superior oblique palsy measured by a synoptometer].

Using a synoptometer we evaluated the surgical effect on the incomitance of the vertical deviation in 26 patients with congenital superior oblique palsy. Either an inferior oblique recession or a superior oblique plication was performed. The two operative procedures reduced the incomitance caused by horizontal change of gaze, but produced incomitance by the vertical change of gaze and the incomitance increased proportionately with change of gaze from down to upward positions, which was not recognized preoperatively. As a result, the hyperdeviation was markedly reduced in the field of action of the overacting inferior oblique muscle. Moreover the surgical effect on the incomitance of the vertical deviation was studied in 13 patients with acquired superior oblique palsy treated with superior oblique plication. This procedure increased not only the incomitance in the upward positions by horizontal change of gaze, but also produced incomitance in adductive positions by vertical change of gaze. Therefore the hyperdeviation of the paretic eye was remarkably overcorrected in the field of action of the antagonist of the paretic superior oblique muscle.

Adolescent↗
PubMed1989

[Surgical treatment of torticollis in cases of congenital nystagmus with strabismus].

To correct compensatory head turn in twelve cases with congenital nystagmus, they were classified into two types according to the relative visual lines of both eyes to each other with respect to the sagittal axis of the head or the median plane of the body. One was termed the symmetrical pattern and the other was termed the asymmetrical pattern. In cases of the symmetrical pattern, a neutral zone exists in which the dominant eye in in the adducted position of gaze with esotropia and in the abducted position of gaze with exotropia. However, in the case of the asymmetrical pattern the neutral zone of the dominant eye is located in the abducted position of gaze with esotropia and in the abducted position of gaze with exotropia. Surgery was performed by shifting the dominant eye to the direction of the sagittal axis of the head in accordance with the degree of ocular deviation in the primary position. In asymmetrical pattern cares, both eyes were surgically shifted in parallel to the direction of the sagittal axis of the head without regard to the types of strabismus. The operation was based on the degree of compensatory head turn. We compared the surgical results the two types. In symmetrical cases, decreasing strabismus was disappointing compared to the head turn, while in asymmetrical cases decreasing head turn was disappointing as compared to strabismus. From these results surgery should be confined to the dominant eye in symmetrical cases, taking as the basis for operation the degree of head turn and not the ocular deviation.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1988

Dynamic analysis of head movements by means of a three-dimensional position measurement system.

By using a newly devised three-dimensional position measurement system, head movements of a normal subject and a patient with congenital strabismus were studied. This system consists of both infrared light-emitting diodes and position-sensitive diodes, which lead to high accuracy and high-frequency response with a position accuracy within 1 mm and angular accuracy within 1 degree. The electro-oculograph was used for measuring ocular movements. The power spectra of head and eye movements showed a similar frequency component and a similar frequency response with respect to the signal inputs of head movements, so there is a close correlation between the two movements.

Adolescent↗
PubMed1985

[Comparison of in vitro antibacterial activities of new cephems against clinical organisms (isolated between June 1983 and January 1984)].

We compared the in vitro antibacterial activities of ceftizoxime (CZX), cefotaxime (CTX), cefmenoxime (CMX), cefoperazone (CPZ), ceftazidime (CAZ), latamoxef (LMOX) and cefotetan (CTT) against 2,729 strains of 11 organisms freshly isolated from 10 medical institutions in Japan between June 1983 and January 1984 and obtained the following results: Against S. pyogenes, LMOX and CTT, which have the methoxy group at the 7 position, were less active than the other drugs. LMOX inhibited 80% of S. pyogenes at 0.78 micrograms/ml; CTT, at 1.56 micrograms/ml; but CZX and CTX inhibited 100% at 0.025 micrograms/ml or lower; CMX, at 0.05 micrograms/ml; and CPZ and CAZ, at 0.20 micrograms/ml. Against H. influenzae, E. coli, K. pneumoniae, P. mirabilis and indole-positive Proteus, these test antibiotics, especially CZX, CTX and CMX, which have the aminothiazolyl methoxyimino group, were potently active. Against S. marcescens CZX and CAZ were more active than the other drugs and against P. aeruginosa CAZ was more active than the other drugs. The test organisms did not tend to acquire resistance to these cephems when our results were compared with the results obtained at the development period.

Bacteria↗