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Biomedical subjects

S H Reisner

Publications and source records attributed to S H Reisner.

At least 73 records · Page 4Linked to original sources

Upper limb standards in newborns.

The present study assists the clinician in determining an abnormal upper limb in the newborn. To define standards for upper limb measurements in the newborn, 198 term and preterm infants (gestational age range, 27 to 41 weeks) were examined. In every case, the gestational age was determined chronologically and clinically, and the total length of the arm, upper extremity and forearm lengths, and total hand and middle finger lengths were measured by two observers using standard techniques. Normal values were determined by plotting the mean +/- 2 SDs for each gestational week v the gestational age.

Anthropometry↗

Occurrence of supernumerary nipples in newborns.

A prospective study on supernumerary nipples (SNNs) was performed on 1,691 consecutively born neonates. We used a new technique for easier routine detection of SNNs. The incidence of this anomaly was one per 40 or 25 per 1,000 live births. Association of other congenital abnormalities with SNNs was not found.

Breast↗

Philtrum length and intercommissural distance in newborn infants.

In order to define standards for philtrum length and mouth width in the newborn infant, 198 term and preterm infants (27 to 41 gestational weeks) were examined. In every case the gestational age was determined chronologically and clinically and the philtrum length and mouth width (oral intercommissural distance) were measured by two observers using standard measurement techniques. Normal values are presented by plotting the mean +/- 2 SD for each gestational week versus the gestational age.

Female↗

Down's syndrome in twins of unlike sex.

The occurrence of Down's syndrome in both dizygotic twins appears to be very rare. A case of twins of unlike sex is reported, in which chromosomal analysis showed trisomy 21 in both of them, while the parental karyotypes were normal. This is the third reported case of such a constellation, and the second one in which infant and parental chromosomal analysis was done.

Adult↗

Assessment of ear length and low set ears in newborn infants.

In order to define normal values for ear length and position in the newborn infant, 198 (87 term and 111 preterm) infants were examined. In every case gestational age was determined chronologically and clinically. Ear length was measured from the superior to the inferior aspects of the ear. Using a horizontal line passing through the inner canthi of the eyes the portion of the ear above this line was measured, determining the position of the ear by its relation to total ear length. Normal values are presented by plotting the mean +/- 2 SD versus the gestational age. Small ears and low set ears are defined as values less than the mean -2 SD.

Ear↗

Tags and bands of the female external genitalia in the newborn infant.

A high incidence of hymenal tags (5.75%) and hymenal bands (2.7%) was found during the routine physical examination of 974 female infants within the first 24 hours of life. Hymenal tags usually disappear spontaneously as the estrogen effect diminishes. If they do not, biopsy should be considered. A simple test is proposed to demonstrate the superficial position of the hymenal band and its lack of connection with an internal structure.

Female↗

Direct hyperbilirubinemia complicating ABO hemolytic disease of the newborn.

A retrospective study of the diagnostic implications of conjugated hyperbilirubinemia complicating ABO hemolytic disease of the newborn (HDN) was done by studying the records of 264 infants with ABO-HDN. Direct hyperbilirubinemia was found to complicate ABO-HDN in 3 per cent of the infants, all being full term. Eighty-seven per cent were female and familial occurrence was noted in half of the cases. Most of the infants presented with anemia on the first day of life. Our data suggest that this is a benign complication of ABO-HDN which clears within a month.

ABO Blood-Group System↗

Retinopathy of prematurity: incidence and risk factors.

A high incidence of retinopathy of prematurity (ROP) was found in the very low-birth-weight infants discharged from the neonatal intensive care unit during the years 1977 to 1980, in spite of frequent monitoring of oxygen use. Although the yearly incidence of ROP in infants weighing less than 1,500 g varied between 35% to 36%, none were blind. The medical records of 65 infants with a birth weight between 501 and 1,250 g; surviving in 1979 to 1980, were reviewed in order to find risk factors for ROP. There were no significant differences between the 34 infants with ROP and the 31 infants who did not have ROP in mean birth weight or mean gestational age. Of 32 possible risk factors examined, the factors significantly associated with ROP were: apnea with mask and bag ventilation; prolonged parenteral nutrition; number of blood transfusions; and episodes of hypoxemia, hypercarbia, and hypocarbia. A highly significant association between hypocarbia and the development of severe ROP was found.

Apnea↗

Replacement of gentamicin by amikacin as a means of decreasing gentamicin resistance of gram-negative rods in a neonatal intensive care unit.

The emergence of resistance in bacteria that colonize infants in a neonatal intensive care unit (NICU) is of great concern and a serious therapeutic problem. During the years 1980 to 1981, continuous surveillance of bacterial colonization was carried out on 499 infants admitted to the NICU of the Beilinson Medical Center. Antibiotic sensitivity testing was performed on all organisms isolated. At the end of 1980 and the beginning of 1981, an increased number of gram-negative rods became gentamicin-resistant. It was assumed that the discontinuation of gentamicin usage and replacement with another aminoglycoside, amikacin, would bring about a reduction in gentamicin resistance. Replacement of gentamicin by amikacin resulted in a significant decrease in gentamicin-resistant Escherichia coli and Klebsiella within 3 to 6 months. The emergence of resistant strains can be detected by surveillance methods and overcome by a change in the antibiotic regimen.

Amikacin↗

Neonatal bilirubin levels and glucose-6-phosphate dehydrogenase deficiency in preterm and low-birth-weight infants in Israel.

Eight hundred preterm (PT) and low-birth-weight (LBW) infants, born during a period of 33 months, were examined for erythrocyte glucose-6-phosphate dehydrogenase (G6PD) activity. Each of 17 infants with G6PD deficiency was compared with the next PT or LBW infant born with normal enzyme activity. The groups were similar with respect to gestational age, birth weight, maximal weight loss, breast or formula feeding and the use of oxytocin during labor. Peak bilirubin levels were significantly higher in G6PD-deficient PT and LBW infants (11.7 +/- 1.4 vs. 9.5 +/- 2.1 mg/dl, P less than 0.001). There were no signs of frank hemolysis, and none of the patients underwent exchange transfusion. Early jaundice and the use of phototherapy were somewhat more frequent among the G6PD-deficient group, but not significantly so. It is suggested that PT and LBW infants born to parents of Asian or North African origin be routinely screened for erythrocyte G6PD activity and monitored for possible jaundice.

Bilirubin↗

Renal anomalies in neonates with spontaneous pneumothorax - incidence and evaluation.

Over a seven year period 23 neonates with spontaneous pneumothorax and/or pneumomediastinum (SPP) were diagnosed in 24,739 live birth infants (0.09 percent). Of these, eight (35 percent) had renal anomalies. Three showed severe renal dysfunction and typical Potter facies and died within 34 hours. Their lungs were shown to be hypoplastic with a reduced lung weight: body weight ratio or a low radial alveolar count. One patient had left hypoplastic and right polycystic kidneys. Four patients with obstructive uropathies did not show the typical facies, and SPP was the only sign leading to their early diagnosis and therapy. We conclude that nephrologic evaluation is indicated in newborns with unexplained SPP and recommend abdominal ultrasound and if indicated renal scan and/or intravenous pyelography as part of the initial evaluation.

Female↗

Sternum length, torso length, and internipple distance in newborn infants.

In order to define standards for sternal length, torso length, and internipple distance in the newborn infant, 198 term and preterm infants (27 to 41 gestational weeks) were examined. In every case, the gestational age was determined chronologically and clinically. Sternal and torso length and internipple distance were measured by two observers using standard measurement techniques. Normal values are presented by plotting the mean +/-2 SD for each gestational week v the gestational age.

Anthropometry↗