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Biomedical subjects

S Gold

Publications and source records attributed to S Gold.

At least 73 records · Page 4Linked to original sources
PubMed1988

The Ilizarov technique.

The Ilizarov method for limb lengthening and reshaping is based on sound clinical investigation and animal laboratory studies. Although new to this country, it has been used successfully in the Soviet Union for 35 years. As with all new procedures, one must learn the technique and become familiar with the apparatus before attempting to perform the surgery. Three case histories are presented which were among the first in the United States to be treated by the application of the Ilizarov technique and external fixator.

Adult↗
PubMed1987

Surgical resection of giant metastatic leiomyosarcoma of the heart.

A 44-year-old woman underwent a hysterectomy for leiomyosarcoma in 1969. Cardiac invasion was detected in 1981 but the tumor was considered inoperable. In 1985, 16 years after hysterectomy, malignant tamponade developed as a result of a massive tumor arising from the left ventricle. Emergency decompression by median sternotomy and tube thoracostomy was followed a week later by tumor resection and simultaneous excision of a lung metastasis with the aid of cardiopulmonary bypass. The cardiac tumor weighed 719 gm. A residual pelvic tumor found on a computed tomographic scan was subsequently removed. She is alive and well 22 months after the operation. Aggressive surgical resection of cardiac and other metastases of this slowly growing tumor can be lifesaving.

Adult↗
PubMed1985

Effects of body temperature elevation on auditory nerve-brain-stem evoked responses and EEGs in rats.

ABRs and EEGs were recorded in anaesthetized rats during whole body hyperthermia. ABR amplitudes were decreased during warming, with little recovery as body temperature was lowered. The latencies of the ABR waves decreased with warming and increased with subsequent cooling. The major latency changes were in the later ABR waves. Warming was accompanied by suppression of the EEG. These results point out that ABR evaluation of patients must take into account elevated body temperatures. Since it has been shown that the rat can serve as a model of the effects of heat on man, an attempt is made to relate these ABR and EEG findings in rats to studies of human psychomotor performance during heat exposure.

Animals↗
PubMed1985

Maturation of auditory brainstem potentials in neonates and infants.

Auditory brainstem evoked potentials (ABP) were recorded in 59 healthy neonates and infants whose age ranged from 3 days to 18 months (6 age groups). Latencies of individual waves and the interpeak latencies (IPL) of I-III, III-V and I-V were analysed. A different maturational pattern was observed in the pontomedullary and the pontomesencephalic segments of the brainstem. Latencies of all waves except wave I were longer in male than in female babies. Establishment of normative data related to the technical variables employed by the individual team is a sine qua non prerequisite for adequate neurological evaluation of ABP.

Auditory Pathways↗
PubMed1984

Radiographic findings in progressive necrotizing "malignant" external otitis.

Twenty-three cases of progressive necrotizing (malignant) external otitis were reviewed. Radiographic evaluation was correlated with clinical disease. CT scanning accurately demonstrated subtle foci of involvement in the skull base which may be clinically unsuspected or go undetected with other studies. Central skull base erosion indicates advanced disease and selects those patients requiring extended antibiotic therapy. Soft tissue thickening of the parapharyngeal space and roof of the nasopharynx also implies advanced disease requiring prolonged therapy. Soft tissue improvement can be visualized on CT. While CT scanning demonstrates the progression of bony disease, it cannot be used to follow resolution of central skull base osteomyelitis. Radionuclide scans provide information regarding the overall extent of the inflammatory process.

Aged↗
PubMed1983

Projective identification: the container and reverie as concepts in applied psychoanalysis.

This paper discusses theoretical and clinical problems experienced in the assessment and treatment of two borderline patients admitted to a psychotherapeutic community. It is proposed that difficulties encountered were related first to the inability of the therapeutic couple (therapist and nurse) to develop a capacity for reverie and containment essential if pathological projections were to be detoxified and made available for reintrojection by the patient. Second, it is proposed that failure relates to the patients' difficulties in developing normal symbol formation with respect either to thought or behaviour, related retrospectively to excessive splitting and pathological projective identification and prospectively to an inability to experience whole object relationships. This in turn is linked to the patients' attack on those capacities which are present in the therapeutic couple.

Adult↗
PubMed1981

Auditory function of Friedreich's ataxia. Electrophysiologic study of a family.

Hearing function and auditory brainstem potentials were evaluated in nine members of three generations of a family affected with Friedreich's ataxia. The characteristic findings were high-frequency sensorineural hearing impairment of varying severity and diminished or absent N1, N2, and N3 responses. These electrophysiologic aberrations correlate topographically with previously reported pathological observations.

Action Potentials↗
PubMed1981

Pontomedullary vs pontomesencephalic transmission time. A diagnostic aid in multiple sclerosis.

Caudal vs rostral transmission time has been studied in patients with multiple sclerosis (MS). In the majority of the cases, prolongation in latency was more severe in the caudal segment, which suggests that this part of the brainstem is more commonly affected in MS. The difference between pontomedullary and pontomesencephalic transmission time yields a variable that may prove a valuable adjunct in the electrodiagnosis of MS.

Adolescent↗
PubMed1981

Auditory brain stem responses in thyroid dysfunction.

A characteristic pattern of ABR was observed in hyper-and hypofunction of the thyroid gland. The most conspicuous change took place in the BSCT. Its value correlated well with the level of serum T4. Dynamic changes of ABR pattern were recorded during the development of myxedema and on return to an euthyroid state. This preliminary study suggests that examinations of ABR may serve as a tool in the overall assessment of thyroid status.

Adolescent↗
PubMed1981

Auditory brain stem responses in cerebellopontine angle tumors.

The characteristic features of auditory brain stem responses (ABSR) are described in seven cases of cerebellopontine angle tumors: five acoustic neuromas, one congenital cholesteatoma, and one meningioma. An attempt is made to correlate the N1 response with the degree of auditory nerve involvement, to gain information about the presence of brain stem displacement, and to evaluate the cranial extension of the lesion by recording responses to contralateral stimuli. The empirical nature of deductions based on crossed stimulation is emphasized. In tumors originating from the VIIIth nerve, the ABSR pattern is characterized by a well-defined N1 complex, indistinct or absent additional responses, and prolonged brain stem conduction time (BSCT) on the affected side whenever its assessment is feasible. Recording from the affected side on stimulation of the contralateral side may show normal responses from stations central to the auditory nerve in cases of small-sized tumors. Medium or large tumors may be accompanied by abnormal N2 and/or N3 responses suggesting involvement of these stations.

Adolescent↗
PubMed1981

Assessment of functional integrity of brain stem auditory pathways by stimulus stress.

The effect of increasing the repetition rate of click stimuli on auditory brain stem responses has been studied in young subjects with normal hearing, in old people and in patients with multiple sclerosis. The most conspicuous effects have been observed in the amplitude of the responses, especially waves II and V, and in the value of the brain stem conduction time. Increased stimulation rates may serve as a method for the assessment of the functional status of the lower auditory pathways in diverse pathological conditions.

Acoustic Stimulation↗
PubMed1981

Speech discrimination scores at low sensation levels as a possible index of malingering.

Persons referred to the clinic for hearing evaluation, aged 17--35 yrs, who during the evaluation yielded inconsistent pure-tone and speech data and were suspected of malingering, were given a monosyllabic Hebraic PB test at 5, 10, 15, and 20 db re their admitted SRT. Group performances were compared at every presentation level to those of normal-hearing young adults. Both groups performed better as levels increased, but the suspected malingerers yielded SDSs at 5, 10, and 15 db significantly higher than controls by 20.8, 12.5, and 5.2 percentage points, respectively. The higher SDSs at low sensation levels (SLs) yielded by the suspected malingerers were assumed to be due to the exaggerated SRTs admitted by them. Furthermore, the performance - vs - level curve of the normals corresponded to that in the literature for English material, while the curve of the suspected malingerers was, in contrast, essentially different. It was concluded that with careful standardization and wide clinical and experimental use, collecting SDSs at low SLs re admitted SRT might produce a potentially valuable additional tool for uncovering malingering.

Adolescent↗
PubMed1979

Auditory potentials of cochlear nerve and brain stem in multiple sclerosis.

Auditory evoked potentials of the cochlear nerve and the brain stem were recorded in ten patients with multiple sclerosis (MS) and four patients thought to possibly have MS. A characteristic pattern materialized, with a prolonged N1-P4 conduction time and absent or small N2 and/or N5 waves. We discuss possible clinical implications.

Adult↗