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Biomedical subjects

S Georgiev

Publications and source records attributed to S Georgiev.

52 records · Page 3Linked to original sources
PubMed1975

[Study of Vibrio strains isolated from swine].

Antigen and biochemical studies were carried out of nine Vibrio strains isolated from pigs, testing their pathogenicity and toxicity for experimental animals. According to their biochemical behaviour six of the strains were shown to belong to type I, three--to subtype I, and on the grounds of their antigenic characteristics six belonged to type I and three--to type II. It was found that the strains producing hydrogen sulfide were more weakly pathogenic and toxic. No substantial differences were found between the strains isolated from miscarrying and normally farrowing sowa originating from pig breeding farms with a record of vibriosis.

Abortion, Septic↗
PubMed1975

[Study of the amniotic fluid of sheep in the normal course of pregnancy and in abortion].

Cytologic, biochemical and immunoelectrophoretic studies were carried out of amniotic fluids in 100 ewes with normal pregnancy and 40 ewes that had miscarried. Each month of pregnancy a total of 20 and 8 animals of the two groups, respectively were studied. It was found that the biochemical and metabolic processes taking place in the fetus lead to changes in the amniotic fluids altering the pH value, the alkali reserve, the content of potassium, calcium, phosphorus, alkaline phosphatase as well as their bactericidal activity. More characteristic changes linked with pregnancy were observed in the cell composition of the amniotic fluids. With advancing in age the increase in cell count was accompanied (staining with Nile blue sulfate) with a rise of the "orange cell" content. The amniotic fluids of ewes with normal pregnancy were found to contain proteins which precipitated with hyper immune sera against blood serum and kidney, heart, and placenta proteins. In ewes that had miscarried the pH values of the amniotic fluids dropped in the months when abortions took place: 7.36, 7.11, 6.90, 6.80 and 6.90, as against 7.41, 7.36, 7.28, 7.17 and 7.18, respectively. Along with pH the alkali reserve also dropped to 37.9 in the first month and 14.20 in the fifth month. In ewes that had miscarried in the 2nd, 3rd, and 4th month these values were 18.90, 14.90, and 13.80 cu. cm, respectively. In cases of abortions the protein composition of the amniotic fluids showed higher levels of the alfa and beta globulins.

Abortion, Veterinary↗
PubMedDate not supplied

[Biomechanics of the metatarsophalangeal joints].

Koehler-Freiberg's disease is found to most commonly manifest itself in the metatarsal head of the second ray. Occasionally it is observed to occur in the metatarsal head of the third and less commonly it is seen to appear in the other rays of the foot. An investigation into probable causes of the disorder calls for consideration of the biomechanical conditions in the region of the metatarsophalangeal joints. A review of the literature pertaining to this matter has failed to reveal any detailed information in this respect and therefore a series of experiments have been conducted involving determination of a) the ground force under the metatarsophalangeal joints and under the toes in normal barefoot walking b) the direction of the flexor tendons and such others that cross the joint and that might play an important role in exerting force between the toes and the ground, c) the geometry of the articulating surfaces and d) the forces that act between the metatarsal head and the corresponding phalangeal joint surface. It is shown that the specific loading of the MP-II joint (due to forces acting across the joint) could amount to nearly twice that to which MP-I is subjected to. This might explain the more frequent occurrence of osteonecrosis of the second metatarsal head as compared to that observed within the head of the first. Furthermore, the direction of the joint resultant force in the MP-II joint is seen to be more dorsally inclined than that in MP-I, which agrees well with clinical findings regarding the site of localized lesions. Lastly, a hypothesis which still requires closer investigation is presented to explain the development of the bone lesions that are known to occur just below the subchondral cortex.

Biomechanical Phenomena↗