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Biomedical subjects

S Fukuchi

Publications and source records attributed to S Fukuchi.

At least 271 records · Page 15Linked to original sources
PubMed1979

Changes in serum isoamylase activities after fibergastroduodenoscopy and colonoscopy. Isoamylase after FGDS and FCS.

The effects of endoscopic examination on the changes in serum amylase activity were investigated in hospitalized patients without salivary and pancreatic disorders. Sixty-nine patients were selected for the peroral fibergastroduodenal endoscopy and twenty-three patients for the peranal fibercolonoscopy. Blood samples were drawn before, immediately after, 4 hrs and 24 hrs after the termination of the examinations. The serum activities of the salivary type isoamylase increased in 7 out of 69 cases 4 hrs after the examination with the fibergastroduodenoscope, but none in all 23 cases after the examination with the fibercolonoscope. On the other hand, the serum activity of the pancreatic type isoamylase did not change following both examinations. A significant rise in serum cortisol levels was induced by both examinations. There were no correlations between the rise in salivary type isoamylase and that in serum cortisol levels. These results did not suggest that the increase of salivary type isoamylase was mediated by the hypophysio-adrenocortical axis. Other possible mechanisms were discussed.

Colon↗
PubMed1978

[Microdetermination of corticosteroids in adrenocortical zones in various adrenal diseases (author's transl)].

Since the relationship between steroidogenic activity and morphological differentiation is not necessarily clear in the human adrenal cortex, aldosterone (Al), cortisol (F) and corticosterone (b) from the adrenal tissues cut into four small pieces (capsule and glomerulosa, outer fascicular, inner fascicular, and reticular zones) on a cryostat immediately after their removal at surgery were estimated by radioimmunoassay in 15 patients with adrenal diseases (8 primary aldosteronism, 1 idiopathic aldosteronism, 4 Cushing's syndrome and 2 pheochromocytoma) and 8 control subjects with other diseases. A larger amount of Al was contained in the outer fascicular zone than in other zones in control subjects. Al showed a high value of 0.16 approximately 7.40 ng/mg tissue in adenomas of primary aldosteronism and a low value of 0 approximately 0.25 ng/mg tissue in adenomas of Cushing's syndrome. A high value of Al was detected in idiopathic aldosteronism but not in the remaining adrenal of primary aldosteronism. In Cushing's syndrome, F showed a high value of 2.58 approximately 12.3 ng/mg tissue in adenoma and a relatively low level of 0.77 ng/mg tissue in carcinoma. A larger amount of F and B was found in the inner fascicular zone than in other zones in the control subjects. These results indicate that the corticosteroid content in each adrenal zone correlates with the morphological findings.

Adenoma↗