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Biomedical subjects

S Friberg

Publications and source records attributed to S Friberg.

At least 73 records · Page 4Linked to original sources

Radiographic measurements of the radio-carpal joint in normal adults.

Radiography of 60 normal wrists was performed in 50 adults to determine the inclination of the distal joint surface of the radius. The central ray was directed 10 degrees proximally in postero-anterior projection and 15 degree proximally in lateral projection. The values obtained were compared with those from perpendicular projections. No dfferences were found between the two p.a. projections. In the lateral projection with the central ray directed proximally the measuring points were better defined, resulting in significantly increased exactness of the measurement. The mean value for the volar inclination was 9 degrees in the latter projection.

Adult↗

Radiographic measurements on the radio-carpal joint in distal radial fractures.

Radiography of 40 wrists with fractures in the distal part of radius was performed. In the lateral view the inclination of the radial joint surface was analysed in different degrees of pronation and supination. The central ray was directed 15 degrees proximally and the results were compared with those obtained with a perpendicular central ray. In the perpendicular projections even moderate differences in pronation or supination between two examinations could seriously alter the measured inclination of the joint surface of the radius. The projection with the central ray directed 15 degrees proximally highly significantly decreased the errors between the measurements when compared to the perpendicular projection. The joint surface was depicted more dorsally inclined than in the perpendicular projection.

Carpal Bones↗

Partition of an organophosphorus compound, dichlorvos, between liquid and liquid crystalline phases.

The partition coefficients for an organophosphorus compound, dichlorvos (2,2-dichlorovinyl dimethyl phosphate), between pure liquids, micellar solutions, and liquid crystalline phases were determined by spectrometric analysis of the dichlorvos content after equilibration and separation of the phases. The results demonstrated the pronounced importance of associated colloid structures on the partition coefficient and showed that the partition coefficient did not display a simple concentration dependence.

Chemistry, Pharmaceutical↗

Concanavalin A and other lectins in the study of tumor cell surface organization.

Cell surface structures of two mouse ascites tumors were studied using lectins. The tumors are sublines of the spontaneous mammary adenocarcinoma TA3 in strain A, differing in two main characteristics. Subline TA3-St grows only in syngeneic mice and has high expression of H-2 antigens. Subline TA3-Ha, in contrast, proliferates in all mouse strains, and has low amounts of exposed H-2 antigens. Concanavalin A (Con A), phytohemagglutinin (PHA) and Helix pomatia anti A hemagglutinin (HP) were used in agglutination tests, in binding experiments with 125I-labelled lectins and also in fluorescence studies with FITC-labelled lectins. Con A and PHA agglutinated the TA3-St cells but not the TA3-Ha cells. However, fluorescein-labelled Con A and PHA were bound to all cells (greater than 90%) of both sublines. Moreover both cell types contained an identical number of Con A receptors. The same result was obtained when the number of PHA receptors on the two sublines was compared. HP agglutinated TA3-Ha cells but not TA3-St cells. However, in this case, the difference in agglutinability between the lines was due to the presence or absence of HP receptors. All TA3-Ha cells contained large numbers of HP receptors. In contrast the majority (greater than 90%) of the TA3-St cells lacked HP receptors. (See article.) Trypsin released the HP receptors from TA3-Ha cells, at the same time making these cells agglutinable by both Con A and PHA. We conclude that the Ta3-Ha cells have a trypsin sensitive surface glycoprotein (or glycoproteins) detectable by HP, which is absent on most TA3-St cells. It is possible that this glycoprotein interferes with the agglutinability of TA3-Ha cells by Con A and PHA; whether it is also responsible for the low expression of H-2 alloantigen on this cell remains to be seen.

Adenocarcinoma↗

The roentgenological end results after caliper treatment of coxa plana with varying degrees of epiphyseal involvement.

The radiological results after caliper treatment of 45 hips with Coxa Plana are presented. The material was grouped and analysed according to the degree of primary involvement of the epiphysis by the necrotic process. It was found that the risk for deformation of the femoral head became significantly higher in the groups with more extensive involvement of the epiphysis. This observation shows that the primary involvement of the epiphysis has a determining influence on the results. It further indicates that if the radiographic results from different materials of Coxa Plana are to be compared consideration must be given to the primary extent of necrosis of the epiphysis.

Child↗