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Biomedical subjects

S Fink

Publications and source records attributed to S Fink.

At least 73 records · Page 4Linked to original sources

Risk management in suspected acute appendicitis.

Acute appendicitis is a disease in which the essential elements for timely diagnosis are available. These elements are a careful history and thorough physical examination, the latter repeated as necessary until clinical judgment indicates that exploratory surgery should be performed or the patient safely discharged. The hospital that does not provide its staff with facilities to do so invites a potentially successful malpractice claim. In the absence of properly documented care, such a claim could include allegations of improper or inadequate evaluation of a person presenting for medical care, negligent medical care based on failure to properly use referral and consultant sources, and failure to provide adequate follow-up (including hospital admission). Such allegations would describe the foreseeable and significant consequences of the adverse event, be it premature discharge or negative exploration. Risk management includes education of hospital administration about the importance of an adequate observation period in this diagnosis, and education of the professional staff about the need for thorough documentation of the serial examinations when surgery is deferred. This article has presented fact, references, and opinion, which should help hospital risk managers to assess the documentation of appendicitis cases now being seen in their hospital, to plan educational interventions with the administration and professional staff, and to assist the hospital collections personnel if payers contest admissions that did not result in surgery.

Appendicitis↗

Correlation of radionuclide urodynamometric and clinical data in 20 men with urinary symptoms.

Radionuclide uroflowmetry was performed in 20 patients. These data were correlated with other urologic data, the treatment decision, and the patient's clinical status five to twelve months after testing. In 19 patients the follow-up period confirmed the expectations of the therapeutic plan. We conclude that the radionuclide uroflowmetry technique provides the urologist with objective data which can assist in the decision to perform surgery.

Adult↗

Gastric emptying in human disease states.

The application of new radioisotope methods in external in vivo scanning has increased our knowledge of how disease and treatment can effect gastric emptying (GE). Solids leave the stomach more slowly than liquids, and conditions causing gastroparesis affect solids before liquids. Gastric mucosal abnormalities and their treatment can affect GE. Diseases of the gastric musculature, including the inflammatory and endocrine myopathies, muscular dystrophies, and infiltrative disorders, can result in significant gastroparesis. Acute and chronic neuropathy may both affect gastric emptying. The latter neuropathies are now the subject of intense investigation with new prokinetic drugs. Finally, abnormal GE may be a major clinical feature of certain severe psychiatric disorders.

Autonomic Nervous System Diseases↗

Update: pharmaceuticals and gastric emptying.

Radionuclide techniques have provided gastric emptying (GE) rate data for liquid, solid, and indigestible intraluminal contents. These data have been collected for basal states and following drug administration. Because the ability of drugs to effect GE may alter the bioavailability of orally administered medication, the latter findings are clinically useful for drugs which secondarily effect GE, as well as those whose primary objective is alteration of gastrointestinal motility. This paper reviews the current understanding of the physiology of GE, followed by an informational review of drugs listed first by medical subspecialty and then based upon special use, including antipyretics, non-narcotic analgesics, and recreational drugs.

Anti-Inflammatory Agents, Non-Steroidal↗

Radionuclide imaging in osteitis deformans.

New knowledge of osteoclastic function and new treatments to reduce osteolytic activity have combined to yield new degrees of biochemical control over the increased rate of bone resorption and formation that characterized osteitis deformans (OD; Paget's disease). We have briefly outlined current concepts, and provided an example of the role radionuclide imaging can play in delineating the skeletal areas involved in this disease.

Bone and Bones↗

Current status of imaging in the diagnosis of acute appendicitis.

The diagnosis of acute appendicitis remains a problem in clinical surgery. Negative appendectomy represents misdiagnosis, and perforation may be the result of delayed diagnosis. The accuracy of diagnosis has improved little in decades, with a rate of 20% for negative appendectomy and 21% for perforation in one large series [Lewis FR: Arch Surg 110:677-685, 1975. Clearly, the need exists for a sensitive yet specific diagnostic imaging tool. The purpose of this paper is to review the role of currently available imaging modalities in the diagnosis of acute appendicitis.

Acute Disease↗