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Biomedical subjects

S Endo

Publications and source records attributed to S Endo.

At least 721 records · Page 40Linked to original sources

CT findings in a case of neonatal acute subdural hematoma.

The CT findings in a case of neonatal acute subdural hematoma are presented. CT demonstrated a crescentic high density area in the subdural space over the left cerebral hemisphere and an oval high density area in the left occipital region. The latter was suspected of being an intracerebral hematoma. Emergency craniotomy revealed that the high density area was due to a subdural hematoma between the occipital lobe and the tentorium cerebelli.

Cerebral Hemorrhage↗

Breast cancer concurrent with hyperthyroidism: a case report.

A case of breast cancer concurrent with hyperthyroidism was reported and the relation between breast cancer and thyroid dysfunction was reviewed. It has been frequently suggested that the incidence of breast cancer is decreased in patients with hyperthyroidism and breast cancer coincidental with hyperthyroidism is rare.

Adult↗

Role of endogenous and exogenous cholesterol in liver as the precursor for bile acids in rats.

There is considerable evidence suggesting that compartmentalized functional pools of cholesterol in the liver contribute differently to the formation of bile acids as the precursor. The present paper deals with the incorporation of [1-14C] acetate and of [1,2-3H] cholesterol carried on lipoproteins (LDL and HDL) into biliary bile acids in perfused rat livers and bile-fistula rats. The results showed that endogenous cholesterol synthesized newly from [1-14C] acetate in the liver was incorporated into both cholic acid and chenodeoxycholic acid in a similar way, while exogenous lipoprotein-[1,2-3H) cholesterol delivered to hepatocytes from hepatic circulation was incorporated into chenodeoxycholic acid at a higher rate.

Acetates↗

Increased body movements during sleep in Gilles de la Tourette syndrome.

Overnight sleep polygrams were recorded form 9 patients with Gilles de la Tourette syndrome (GTS). Six of 9 patients had abnormal electroencephalograms, but no specific abnormalities were detected. Body movements and twitch movements during sleep were analyzed. At all stages of sleep, body movements during sleep were more frequent in cases of GTS than those in normal controls. Twitch movements in stage REM of sleep were significantly increased in GTS. These results are consistent with the idea that GTS is due to an imbalance between the central neurotransmitters, catecholamine and serotonin.

Child↗

Influence of ACTH therapy on overnight sleep polygrams in infantile spasms.

Overnight sleep polygrams were recorded before and during therapy in nine patients with infantile spasms. Results showed that ACTH therapy increased the waking time and decreased rapid eye movement sleep. Thus it caused sleep disturbance in patients with infantile spasms. During ACTH therapy the number of rapid eye movements/min and the pulse rate decreased significantly. Body movements/min also decreased, but not significantly. These results suggest that ACTH therapy may inhibit functions of the central nervous system. The respiratory rate increased during ACTH and clonazepam therapy, probably in association with the decrease or the absence of seizures. These findings indicate the necessity for further studies on whether ACTH therapy is really of value in patients with infantile spasms, and show that if ACTH is given, the period of therapy should be as short as possible.

Adrenocorticotropic Hormone↗

Persistence of the circadian rhythm of REM sleep: a variety of experimental manipulations of the sleep-wake cycle.

Many studies of nocturnal sleep, daytime naps, and phase shifts of sleep time indicate that rapid eye movement (REM) sleep has a circadian rhythm with an acrophase in the early morning, whereas slow wave sleep (SWS) correlates positively with the length of prior wakefulness. We confirmed that REM sleep has a stable circadian variation; large REM sleep amounts occurred in morning naps despite increase of SWS, owing to 1 night of total sleep deprivation. Heart rate and oral temperature both continued to show a circadian rhythm in spite of 1 night of total sleep deprivation. The lowest point of both cycles occurred in the early morning and the highest point in the late afternoon. The amount of REM sleep was largest near the low point of the circadian cycle of oral temperature and heart rate, and smallest at the high point, indicating a phase reversal relationship between the circadian rhythm of REM sleep and the autonomic functions. During 1 week of absolute bed rest under entrained conditions, subjects were most able to sleep near the low point of their oral temperature cycle and least able to sleep near the high point, and the amount of REM sleep was largest near the low point of the oral temperature and smallest at the high point.

Adult↗

[A case of intracranial mesenchymal chondrosarcoma--changes observed by computed tomography before and after radiotherapy (author's transl)].

Intracranial mesenchymal chondrosarcoma is very rare, only 14 cases being reported in Europe and in the United States of America. Recently we experienced a case in which the follow-up indicating computed tomograms (CT) demonstrated interesting data on the radiosensitivity of this tumor. The patient, a 14-year-old female was admitted to out hospital with the complaint of left hemiplegia which had gradually progressed. CT revealed an area spreading upward from the right median base of the skull and consisted of two components showing (A) a density as high as that of calcium and (B) a density higher than that of surrounding brain tissue, but much lower than that of calcium. Temporoparietal craniotomy was performed to react approximately one-half of the tumor. Histological finding revealed mesenchymal chondrosarcoma. The component-A was though to be a cartilaginous tissue, and-B to be an undifferentiated mesenchymal tissue. Postoperative irradiation of 7,000 rad was initiated. The effect of radiotherapy as seen on computed tomograms is as follows, (1) decrease in the volume of the tumor by 26%, (2) decrease in density and enhancement of the area which is considered to be the undifferentiated mesenchymal cells, (3) mild reduction of the area which is considered to be the cartilaginous tissue, and (4) a very high density of the entire tumor similar in degree to that of the bone one year later. These results suggested that radiotherapy is effective for this tumor.

Adolescent↗

[A case of acute subdural hematoma in one-day-old baby--with special reference to its CT findings (author's transl)].

The authors describe and discuss a case of acute subdural hematoma originating from the lacerated tentorium of 22 hour-old newborn. CT scan revealed crescent high density area in the subdural space between the left frontal area and the occipital area. Another high density area was seen in the left occipital area which was suspected as intracerebral hematoma preoperatively because of its rather intramedullar location. Large craniotomy was performed 22 hours after delivery, evacuating 70 gm subdural hematoma. Bleeding point was determined as lacerated tentarium about 1 cm length. No intracerebral hematoma was found. Postoperative course was uneventful and he is showing normal development. It is now concluded that supratentorial subdural hematoma originating from tentorial laceration at delivery could be misdiagnosed as intracerebral hematoma on CT scan. Anatomical structure should be always compared when CT scan study is performed.

Acute Disease↗

[An anterior communicating artery aneurysm complicated by chronic subdural hematoma--a case report (author's transl)].

A 53-year-old housewife was admitted to the Department of Neurosurgery, Toyama Medical and Pharmaceutical University on June 6, 1980, because of disorientation, urinary incontinence and left hemiparesis. She had experienced "a fit of severe headache" many times for five years. On May 12, 1980, she experienced an abrupt, severe headache in a lavatory and was immediately brought to a nearby hospital. Her symptom was recovered gradually for a week but she experienced sudden onset of severe headache again on May 20. Subsequently, her state of consciousness gradually worsened and left sided hemiparesis arose. On admission, cerebral angiograms revealed an aneurysm of an anterior communicating artery and a subdural hematoma over the right hemisphere. On the third hospital day, radical operation was performed by bifrontal craniotomy. Neck of aneurysm was ligated and clipped successfully and dark brownish semiliquid contents of chronic subdural hematoma was evacuated. The lacerated portion of arachnoid with some distance from the aneurysm was observed and subarachnoid hemorrhage was thought to enter subdural space through this portion. Post-operative course was uneventful. Nine cases of intracranial aneurysms complicated by chronic subdural hematoma were reported previously, but an anterior communicating artery aneurysm case was not in these cases. We have some discussion about cerebral aneurysms complicated by chronic subdural hematoma, especially about the pathogenesis of chronic subdural hematoma.

Chronic Disease↗

[Measurement of regional blood flow using hydrogen gas generated by electrolysis (author's transl)].

Electrolytically generated hydrogen gas used to measure local blood flow by Stosseck et al. The data obtained by their method, however, did not correlated well with that obtained by original Aukland's method, hydrogen clearance method. We have tried to record the concentration of hydrogen gas after electrolytic generation of hydrogen gas at the white matter of the mongrel dogs. As a result, we found that its curves could be approximated to monoexponential curves during the first several minutes. This fact was also noticed in the experiment, in which circulation had been stopped due to cardiac arrest. A simple equation to calculate the regional blood flow was brought out through the approximation mentioned above. The values calculated by this new equation correlated well with that obtained by original hydrogen clearance method. This new method to detect the regional blood flow is simple and easy. Therefore it may contribute to some experiments, especially to the experiments with small animals.

Animals↗