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Biomedical subjects

S Dexeus

Publications and source records attributed to S Dexeus.

At least 19 recordsLinked to original sources
PubMed1999

Invasive micropapillary carcinoma. Distinct features of a poorly recognized variant of breast carcinoma.

INTRODUCTION: Invasive micropapillary carcinoma (IMC) is a histological variant of breast cancer with a poor prognosis. MATERIAL AND METHODS: Pathological findings of 15 cases of IMC are compared with those of 144 invasive duct carcinoma (IDC) and 10 invasive papillary carcinoma (IPC). RESULTS: Only 33% of cases were diagnosed in stage I. Mean tumor size was 2.3 cm. Nuclear grade 3 was found in 60% of cases, aneuploidy in 78%, and 92% had hormone receptors. Nine patients showed lymph node metastasis. Tumor size, nuclear grade, mitotic rate and lymph node involvement were higher in IMC when compared with IDC grade I and IPC, but not when compared with IDC grade II and III. Four cases of IMC (27%) recurred before two years. Recurrences and lymph node metastases showed the same architectural pattern as the primary tumor. DISCUSSION: IMC shows a high incidence of lymph node involvement and a high early recurrence rate.

Adult↗
PubMed1999

Epidemiology of preinvasive lesions.

OBJECTIVE: Review of epidemiological data on pre-invasive cervical lesions. MATERIAL AND METHODS: Literature review and analysis of data from our Department. RESULTS: Prevalence of data on preinvasive cervical lesions varies widely and depends on factors such as differences among countries or regions and among ethnic groups, and especially, differences in the type of population studied. Most important risk factors are: number of sexual partners, smoking, contraceptive use, HPV, age at first intercourse, and screening. CONCLUSIONS: In order to reduce risk, pap smears should be performed regularly, safe sex practices should be recommended, and the use of tobacco products should be avoided.

Adult↗
PubMed1998

Hyperprolactinemia: an inductor of neoplastic changes in endometrium? A report of two cases.

Estrogen-dependent endometrial carcinomas habitually arise through a precursor lesion such as endometrial hyperplasia. The hormonal environment of these patients remains unclear. Two cases of neoplastic changes in the endometrium of patients with a chronic hyperprolactinemia are presented. Despite the treatment with bromocriptine both patients developed endometrial adenocarcinomas. Possible mechanisms involved in the pathogenesis of these tumors are discussed.

Adenocarcinoma↗
PubMed1998

Survival in cervical cancer.

PURPOSE OF INVESTIGATION: To analyze survival rates for cervical cancer cases seen in our institution. METHODS: All cervical cancer cases seen between 1982 and 1996 were included. Survival analysis was performed using the Kaplan-Meier estimator. RESULTS: One hundred forty nine cases were analyzed, with a mean age of 50 years. Overall, 5-year survival was 73%. Disease-free survival ranged from 68% at 12 months to 6% at 5 years. For women under 40 years of age, 5-year survival was 74%, while for those older than 40 years it was 69%. CONCLUSION: The results seen in our Department are similar to those found in other developed countries.

Adolescent↗
PubMed1997

Transvaginal sonographic appearance of functional ovarian cysts.

Knowledge of the nature of ovarian lesions is important in order to establish the correct treatment and, especially, to detect ovarian cysts that do not require surgical treatment. With the purpose of demonstrating the utility of transvaginal sonography with colour Doppler of ovarian functional ovarian cysts, 378 ovarian tumours were studied, comparing sonographic diagnosis with pathological findings. Sensitivity and specificity of colour Doppler transvaginal sonography to detect functional ovarian cysts were 84.6 and 99.2% respectively. Positive and negative predictive values were 98 and 93.5% respectively. In our experience, transvaginal sonography with colour Doppler is a useful technique in the diagnosis of ovarian pathology.

Adult↗
PubMed1996

The European study of assisted reproduction families: family functioning and child development.

Findings are presented of a European study (conducted in the UK, Italy, Spain and The Netherlands) of family relationships and the social and emotional development of children in families created as a result of the two most widely used reproductive technologies, in-vitro fertilization (IVF) and donor insemination (DI), in comparison with control groups of families with naturally conceived child and adoptive families. Mothers of children conceived by assisted reproduction expressed greater warmth towards their child, were more emotionally involved with their child, interacted more with their child and reported less stress associated with parenting than mothers who conceived their child naturally. Similarly, assisted reproduction fathers were found to interact more with their child and to contribute more to parenting than fathers with a naturally conceived child. With respect to the children themselves, no group differences were found for either the presence of psychological disorder or for children's perceptions of the quality of family relationships. The findings relating to the quality of parenting and the socio-emotional development of the children were similar in each of the four countries studied.

Adoption↗
PubMed1992

Papilloma virus infection. Precancer and epidermoid cancer.

We present a review of the relationship between Human Papillomavirus (HPV), Precancer and Epidermoid Cancer of the uterine cervix, Co-factors that contribute in cervical carcinogenesis and the mechanism through which Papillomaviruses transform normal cells into neoplastic cells by inducing an overproduction of the encoded proteins. We also offer final remarks and conclusions on this pathology that increases its incidence every year.

Carcinoma, Squamous Cell↗
PubMed1981

Oncological indications of hysteroscopy.

On the basis of our experience, we regard hysteroscopy as an important step in oncological propedeutics whenever performed by doctors of an endoscopic unit having experience of the subject. We believe it has a very important role in differential diagnosis of uterine bleedings, in the correct classification of endometrium carcinomas and in the control of non surgical treatments of endometrium carcinomas. It will be increasingly used in specialized hospitals.

Curettage↗
PubMed1977

Colposcopy.

Explore the source record for details and available documents.

Adenocarcinoma↗