Biomedical subjects

S Crusius

Publications and source records attributed to S Crusius.

3 recordsLinked to original sources

PubMed1993

Pre- and perinatal infections due to human herpesvirus-6 and Epstein-Barr-virus with lethal outcome or severe residual encephalopathy.

The Human Herpesvirus-6 (HHV-6) infection causes exanthem subitum (in typical cases) and a wide range of other symptoms. So far no prenatal or perinatal infections have been reported. For HHV-6 the prenatal infection should be extremely rare, because more than 95% of adults are immune in Germany. Two own cases reported here document that pre- and perinatal HHV-6 infection does occur and can provoke dramatic clinical symptoms of illness with death or cerebral defects like other prenatal herpesvirus infections (HSV, VZV, CMV etc.).

Antibodies, Bacterial↗

PubMed1989

[Studies with temocillin].

This is a report about microbiological investigations with a new Penicillin-derivate. Temocillin is the first beta-lactamase stable Penicillin with an excellent bactericidal effect against almost all clinically important gram-negative aerobic germs. The antibacterial activity of Temocillin was determined against 355 multiresistent Enterobacteriaceae-strains. We ascertained minimal bacteriostatic and the minimal bactericidal concentration with help of macrodilution-test. The ratio of resistant strains amounted to 0.8%. In vitro investigations with the combination Temocillin and Gentamicin (checker-board-technique) showed 91% indifference and 9% addition, respectively, in 35 Enterobacteriaceae-strains, investigated. Resistances against Temocillin and Ampicillin were cultured through subinhibitory concentrations to predict parallel resistances possible.

Bacteriuria↗

PubMed1986

[Bacterial meningitis].

A survey is given of important bacterial pathogens of meningitis. It is referred to the necessity to include rare pathogens into the differential-diagnostic considerations. The importance of the microbiological diagnostics and the empiric initial therapy for the prognosis of the bacterial meningitis is discussed.

Anti-Bacterial Agents↗