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Biomedical subjects

S Cotoi

Publications and source records attributed to S Cotoi.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

Three patients with branch to branch reentrant ventricular tachycardia. Diagnostic and therapeutic considerations.

Three patients with repetitive episodes of relatively slow rate (170 beats per minute) ventricular tachycardia, with right bundle branch block (RBBB) QRS morphology during arrhythmia are presented. The clinical and electrophysiological characteristics and the therapeutic problems raised are analysed. The branch to branch reentry mechanism was considered as the underlying mechanism. The peculiar characteristics found in our cases are: almost normal heart, except right bundle branch block in two and left anterior hemiblock in one patient; relatively slow ventricular rate during tachycardia; delayed retrograde ventriculo-atrial conduction during tachycardia; the onset of tachycardia related to atrial or ventricular premature beats; the possibility to stop the tachycardia through ventricular pacing; therapeutical point of view, DC shock, ventricular pacing and iv mexiletin HCl were highly effective, but not iv lidocaine.

Bundle-Branch Block↗
PubMedDate not supplied

Antiarrhythmic effects of verapamil given in sublingual way.

In order to eliminate the first pass through the liver where the drug is deactivated, 80 mgs verapamil was given in sublingual way in a) 10 patients with supraventricular tachycardias where in 7 instances sinus rhythm was obtained after 15-30 minutes, b) in 18 patients with atrial fibrillation and in 5 with atrial flutter with rapid ventricular rate, where a significant slowing down of ventricular rate was obtained after 20 minutes. The sublingual way of verapamil administration is a simple, effective and safe procedure in the treatment of tachyarrhythmias.

Administration, Sublingual↗
PubMedDate not supplied

Experimental validation of sino-atrial conduction time using sinus node potential recording, right and left atrial continuous pacing method.

In an experimental study indirect sino-atrial conduction time (SACT) was measured, using continuous pacing method from right and left atrial sites, and compared with direct SACT obtained from sinus node potential recording, all the determination being done before and after autonomic blockade. The distance between the two sites of stimulation may be taken into account as a correction factor for SACT determination. The SACT obtained with sinus node potential technique is the same as the indirect SACT after autonomic blockade. These findings are valuable for SACT determination with transesophageal pacing method. Left atrial pacing, thus transesophageal pacing, is a valuable method in estimating the SACT, but a time correction and autonomic blockade is required in order to obtain a real value, eliminating the extrinsic influences.

Animals↗
PubMedDate not supplied

Transesophageal pacing technique in the estimation of sinus node function.

A personal noninvasive transesophageal pacing technique for the estimation of sinus node function is presented. With a pacemaker device and an esophageal pentapolar catheter, using a correction factor for the left atrial site of stimulation, it is possible to calculate the sinus node recovery time, sinoatrial conduction time and sinus node effective refractory period, before and after autonomic blockade as accurately as by the intracavitary technique.

Autonomic Nerve Block↗
PubMedDate not supplied

Cardioversion of atrial fibrillation to sinus rhythm using quinidine given in rapid administration.

A rapid method using quinidine sulphate for the cardioversion of atrial fibrillation is presented. Intensive administration of the drug allows the use of lower doses (mean dose 1.159 g quinidine sulphate), with high convertibility rate (69.76%); 7 hours after the start of the procedure 94 per cent of the patients were already in sinus rhythm. The short duration of this procedure allows careful monitorization of the patients.

Adult↗