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Biomedical subjects

S Chandrasekar

Publications and source records attributed to S Chandrasekar.

60 records · Page 4Linked to original sources
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A comparative study of creatinine clearance rate in type I (IDDM) and II (NIDDM) diabetic patients.

The endogenous creatinine clearance test was done in 14 Type I and 15 Type II poorly controlled diabetic patients and compared with respective age matched healthy volunteers. Type I diabetics had significantly lower creatinine clearance rate, body mass index and serum albumin levels when compared to their control group. In Type II diabetics these values remained unaltered. Both Type I and Type II diabetics had significantly higher blood sugar and glycosylated haemoglobin levels. The creatinine clearance rate had significant positive correlation with patients' body mass index and serum albumin levels. This suggests that the undernutrition of Type I diabetics may be responsible for the decreased creatinine clearance.

Adult↗
PubMedDate not supplied

Reaction time in clinical diabetes mellitus.

Visual and auditory reaction times were studied in patients suffering from diabetes mellitus and age matched normal control subjects. Auditory reaction times were shorter than visual reaction times in control subjects as well as diabetic patients. In diabetic patients, there was significant prolongation of visual as well as auditory reaction times. Further studies of reaction times for various modalities may provide a better insight into the neurological disturbances in diabetes mellitus.

Adult↗
PubMedDate not supplied

Sensory nerve conduction in diabetes mellitus and diabetic neuropathy.

Electrophysiological evaluation of conduction in sensory fibres of right ulnar and median nerves were carried out in normal subjects and diabetics with and without neuropathy. The sensory conduction velocities of ulnar as well as median nerves are significantly depressed in both groups of diabetics, particularly in those with neuropathy. The diabetics with or without neuropathy require a higher strength of stimulus for conduction in both median and ulnar nerves as compared to the normal subjects. The amplitude of action potentials is also lowered in both ulnar and median nerves of the two groups of diabetics. Estimation of conduction velocities of sensory fibres can be considered as a more useful parameter than the measurement of amplitude of action potentials in the diagnosis and evaluation of neuropathy in diabetics. It is concluded that assessment of sensory nerve conduction in median nerve is a better indicator than that of ulnar nerve for this purpose.

Action Potentials↗