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Biomedical subjects

S Calderon

Publications and source records attributed to S Calderon.

At least 37 records · Page 2Linked to original sources

Developmental arrest of tooth bud after correction of mandibular fracture.

A case of multiple fractures of the mandible following a car accident in a five-year-old patient is reported. The fracture line passed distal to the first molar tooth bud. The fracture was treated by wire osteosynthesis and skeletal fixation. During the ensuing 18 months, a gradual arrest of the development of the first molar tooth bud was radiologically observed. The eruption process had not been disturbed, and the tooth erupted at the age of 6 1/2 years. Since the distal root had completely failed to develop and the mesial roots showed a diminished size, the tooth was extracted. Histopathological examination revealed disturbed dentin apposition, there was almost complete obliteration of the pulp chamber by globular dentin, and evidence of root resorption.

Child, Preschool↗

Radiographic features of anterior buccal mandibular depression in modern human cadavers.

The anterior buccal mandibular depression (ABMD) becomes significant when evaluating edentulous patients prior to implant insertion. The features of the ABMD in dry mandibles from ancient populations have been reported. In the present study the prevalence and radiological appearance of the ABMD and the influence of soft tissue superposition on its radiological detectability in the jaws of modern human cadavers were evaluated. The prevalence of ABMD was 32%. The presence of soft tissue significantly influenced the radiopacity of the ABMD area and the degree of definition of the borders (p=0.0003 and 0.0001 respectively). Changes in the trabecular pattern were observed in 36% of the cases without soft tissue compared with 29% with soft tissue. The ABMD was more readily detected on CT scans than on conventional periapical or panoramic radiographs.

Age Distribution↗

Flexible waveguides for IR laser radiation and surgery applications.

Flexible plastic waveguides were developed to deliver IR radiation, especially at 10.6 microns, which is the CO2 laser radiation wavelength. The waveguide is made from teflon tube with the inner wall coated with a metal layer and a dielectric overlayer. The internal diameter (ID) is 1.0 mm, length 1.0-1.2 m, and the distal tip decreases moderately to ID approximately 0.6 mm. The distal part on the last 10 centimeters is coated externally with a metal layer. Maximum power that can be delivered at the outlet is approximately 30 W and 10.6 x 10(3) W/cm2. This type of waveguide was used in several medical operations to evaluate its cutting characteristics and the resistances to heat reflection from the tissue while operating in orifices containing liquid substances.

Carbon Dioxide↗

Head and neck manifestations of tumoral calcinosis.

Intraoral facial and laryngeal features of tumoral calcinosis are reviewed in six patients of Jewish-Yemenite descent. Extraoral features included calcified masses, erythematous patches, and angular cheilitis. Oral soft tissue findings included papillary hyperplasia of the lip vermilion and velvety-red macules on the tongue, palate, and buccal mucosa. Gingival findings included advanced periodontitis and an erythematous marginal gingivitis. In all patients, orthognathic evaluation revealed a concave profile, retruded maxilla, and relative mandibular prognathism. Although previously reported clinical dental abnormalities were not present, extracted teeth demonstrated abnormal dentin. Hoarseness was present in all patients and was the earliest appearing feature in two patients. The appearance of these head and neck findings preceded the classical manifestations of tumoral calcinosis and may be helpful in the early diagnosis of this entity. The varied reported features of tumoral calcinosis support the notion that this disease may present multiple formes frustes with variable clinical expressivity.

Adolescent↗

Peripheral osteoma of the mandible: a study of 10 new cases and analysis of the literature.

Ten new cases of peripheral osteoma of the mandible are described. These lesions are uncommon and only 15 other cases have been reported in the English language literature over the past 30 years. There is evidence to suggest that the peripheral osteoma of the mandible is a traumatically induced reactive lesion and that muscle traction plays a role in its initiation. In view of this possibility, the term "parosteal osseous hyperplasia" may be more appropriate for those lesions in which a positive history of trauma preceded the onset.

Adolescent↗

Radiological findings in jaws and skull of neurofibromatosis type 1 patients.

Maxillary and mandibular lesions in neurofibromatosis Type 1 (NF1) in patients are described. Radiographic manifestations include radiolucent lesions with well-defined, poorly-defined or irregular diffuse borders. Mandibular lesions were not associated with the inferior alveolar nerve as it coursed within the mandible. In three patients the lesions extended considerably into the cranial bones. The necessity for routine radiographic and CT evaluation of NF1 patients is emphasized.

Adolescent↗

PCP: a review of synthetic methods for forensic clandestine investigation.

A review of the synthetic routes to phencyclidine (PCP, 1-(1-phenylcyclohexyl)piperidine) available in the open literature is presented. The emphasis herein is directed toward the forensic investigation of clandestine PCP laboratories. Six published synthetic routes to PCP/analogs are discussed. Each method is rated for overall yield, degree of difficulty and potential hazard, in order to assist the forensic chemist in evaluation of a particular clandestine operation. One clandestine recipe is illustrated and discussed.

Forensic Medicine↗

Epidermal nevus syndrome with maxillary involvement.

A female patient with epidermal nevus syndrome is reported. There were linear epidermal nevi, hemihyperplasia of the limbs and tongue, macrocephaly, several ophthalmic malformations, and multiple radiolucent lesions in the limbs and sacroiliac region. At age 14 years, she developed a giant cell granuloma of the maxilla.

Abnormalities, Multiple↗

Intraoral acinic cell carcinoma.

Three cases of acinic cell carcinomas in minor salivary glands of the oral cavity are reported. The tumors were slow-growing and asymptomatic and were treated by wide local excision. A long-term follow-up showed no metastasis. One patient had local recurrence. Generally, this malignant tumor has the potential to recur and metastasize many years after initial diagnosis and treatment. Total excision has been the established treatment of choice. The contribution of radiotherapy and chemotherapy remains unclear.

Aged↗

Techniques for ensuring the lateral position of the proximal segment following intraoral vertical ramus osteotomy.

Continual refinements of the surgical technique and instrumentation for the intraoral vertical ramus osteotomy have made it a preferred procedure for mandibular setback, especially in asymmetrical cases. However, there may be intraoperative difficulty in lateral positioning of the proximal segment, which is frequently trapped medially. Three techniques for lateral relocation of the medially displaced proximal segment are described. Techniques designed to prevent this medial displacement also are presented.

Humans↗

Head, neck, and maxillofacial childhood Burkitt's lymphoma: a retrospective analysis of 31 patients.

Thirty-one children with Burkitt's lymphoma of the head, neck, and maxillofacial region diagnosed between 1976 and 1988 were reviewed. The age range was 2 to 17 years (median, 7.2 years), and 77.4% were males. The most common presenting symptoms were detectable masses, floating and/or painful teeth, enlarged cervical lymph nodes, sore throat, and neurologic signs. The predominant primary tumor sites were the jaws and tonsils. All patients were staged by a clinical staging system, 17 of them having stage I-II, and 14 stage III-IV. Levels of lactate dehydrogenase and ferritin were the only significant laboratory parameters correlating with initial staging and disease-free survival. Radiologic features in the jaws were poorly circumscribed destructive lytic lesions with migration and crypt destruction of unerupted teeth buds. Complete disappearance of these findings was noted after successful chemotherapy and clinical regression of the tumor. Eighteen (58.1%) patients attained complete remission with a follow-up of 5 to 100 months. Stage was the most significant variable affecting outcome, with 90.2% disease-free survival of stage I patients, 72.4% of stage II, and 18.2% of stage III-IV. Based on these results, it is concluded that localized (stage I and II) Burkitt's lymphoma is responsive to chemotherapy and thus has a favorable prognosis.

Adolescent↗

Sarcoidosis with oral involvement.

A case of sarcoidosis with bilateral hilar lymphadenopathy and multiple submucosal papular oral mucosa lesions is presented. The clinical signs and symptoms described in this case are not uncommon, and their distinguishing features may expedite accurate diagnosis. Early incisional biopsy of the oral mucosa appears useful for histopathologic proof of the diagnosis.

Acute Disease↗

Simultaneous occurrence of a congenital lateral upper lip sinus and congenital gingival cyst: a case report and discussion of pathogenesis.

The simultaneous occurrence of a congenital lateral sinus of the upper lip and of a congenital gingival cyst in a newborn boy is reported. The sinus extended to a depth of 10 mm and was lined by a parakeratinized squamous epithelium. The gingival cyst appeared as a 1 cm palatal enlargement lingual to the maxillary alveolar ridge and demonstrated a thin epithelial lining with localized plaquelike thickenings and occasional clear cells with vacuolated cytoplasm. There was no familial history of congenital deformities, and no additional abnormalities were noted. These two epithelium-lined structures show a clear topographic and morphologic relationship, and they may share a common embryologic origin. It is suggested that they derive from epithelium remaining subsequent to the union of the maxillary process and medial nasal process mesoderms.

Child↗