Search PubMed⌕ Search

Biomedical subjects

S C Yeoh

Publications and source records attributed to S C Yeoh.

21 records · Page 2Linked to original sources

Adenomyoma of the pylorus presenting as intestinal obstruction with pseudomyxoma peritonei--a case report.

Adenomyoma of the stomach is an exceedingly rare and benign tumour. We report here what we believe to be the first documented case in Singapore. Our patient is unique in three respects; an eight-week old infant presented with signs and symptoms of intestinal obstruction. Operative findings showed a small tumour in the pylorus of the stomach. The abdominal contents were covered with a colourless mucous slime, giving an appearance of pseudomyxoma peritonei. This is a feature which has not been hitherto reported. Microscopically, the lesion was consistent with adenomyoma of the pylorus. The interesting feature is an abundant production of mucin, with rupture and spillage of mucin in some of the glandular structures. We believe that this may account for the appearance of a pseudomyxoma peritonei seen in our patient.

Diagnosis, Differential↗

Quantitative comparison of prolactin production by decidua compacta and spongiosa from the first trimester elective termination of pregnancy.

Prolactin (PRL) producing capacity was studied in explants of decidua compacta and decidua spongiosa obtained from 41 patients undergoing termination of pregnancy at gestation 6 to 12 weeks. In vitro PRL producing capacity, expressed as mIU/g protein, of the decidua compacta was significantly higher (P < 0.05) than those of decidua spongiosa. Production of PRL increased with gestation from 6 to 12 weeks with a more rapid rate at the later gestation. The pattern of increase fitted significantly (P < 0.0001) to the exponential model for both decidua compacta and decidua spongiosa. The exponential regression equations for decidua compacta and decidua spongiosa were (ln y = 4.25 + 0.19x) and (ln y = 2.80 + 0.31x) respectively. Hence, although both decidua compacta and decidua spongiosa had a similar pattern of increase in PRL production, the rate of increment was significantly greater in decidua spongiosa than in decidua compacta. These findings suggest that separating decidua compacta and decidua spongiosa of the first trimester would reduce the heterogeneity of decidual tissue and offer a new approach to the studies of the synthesis, release and regulation of PRL production by human decidua.

Abortion, Induced↗

Retroperitoneal endodermal sinus tumor. Report of a case with an abnormal cervicovaginal smear.

An unusual case of an endodermal sinus tumor arising in the retroperitoneum and invading the fallopian tube is reported. The patient presented with malignant cells mimicking adenocarcinoma in the cervicovaginal smear. The differential diagnoses of such cells in cervicovaginal cytology are discussed. The cytohistologic, immunohistochemical and ultrastructural findings of the tumor are correlated.

Adult↗