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Biomedical subjects

S Bank

Publications and source records attributed to S Bank.

At least 91 records · Page 5Linked to original sources
PubMed1984

Strictureplasty. An alternative in the surgical treatment of Crohn's disease.

A patient with severe, multilevel, partial obstruction of the jejunum and ileum secondary to Crohn's disease successfully underwent strictureplasty of the stenotic areas as described. Intestinal length was fully preserved. Complete healing and patency without fistulization was observed on reexploration seven months later for stenosis of previously unaffected areas (some of which were again successfully treated with strictureplasty ). When resection threatens the patient with extensive loss of small-intestine length, strictureplasty appears to be a viable alternative.

Adult↗
PubMed1984

Antacid versus sucralfate in preventing acute gastrointestinal bleeding. A randomized trial in 100 critically ill patients.

A randomized, controlled trial of sucralfate versus antacid as prophylaxis against upper gastrointestinal bleeding was carried out in 100 critically ill intensive care unit patients. Both groups were comparable with regard to sex, age, duration of prophylaxis, and the number of risk factors per patient. There was no gross bleeding in any of the patients. Three of the 48 sucralfate patients and 2 of the 52 antacid patients showed strongly positive results of Gastroccult tests of three successive hourly samples of gastric aspirate and were considered treatment failures. We conclude that sucralfate therapy is as effective as an antacid regimen in the prevention of gastrointestinal bleeding in critically ill patients. In view of a considerable savings in nursing time, it offers the opportunity for considerable reduction in the cost of intensive care while providing effective protection.

Aluminum↗
PubMed1983

Failure of inhibitor assay to determine isoamylase distribution.

Isoamylase distribution in the urine of normal individuals and patients admitted to the hospital with hyperamylasemia was determined by a wheat inhibitor mmethod and compared to results obtained by cellulose-acetate electrophoresis. We report two cases where the inhibitor ethod failed to give accurate results in urine, as well as serum, when compared to both electrophoresis and column chromatography. The discrepant results were due to the unexpected inhibition of P isoamylase.

Chromatography↗
PubMed1983

Prevention of experimental duodenal ulcer in the rat by sucralfate.

We examined the ability of sucralfate to prevent secretagogue induced duodenal ulcer in the rat. Sucralfate was administered orally in dosage schedules of 50 mg, 100 mg or 200 mg before and at 3 and 6 hr after commencing a 24 hr continuous infusion of pentagastrin and bethanechol. The animals were sacrificed at 24 hr and the number and severity of ulcers was scored. Ulcers developed in all 9 control rats, in 8 of 9 on the 50 mg dose, in 4 of 9 on the 100 mg dose, and in only 1 of 9 on the 200 mg dose of sucralfate. We conclude that sucralfate prevents the formation of secretagogue induced duodenal ulcer in the rat.

Aluminum↗
PubMed1983

Macroamylase in the pleural fluid of a patient with lymphoma.

A patient with a macroamylase in pleural fluid is described. A diagnosis of recurrent pleural effusion due to chronic relapsing pancreatitis had been made on the basis of hyperamylasemia, high pleural fluid amylase, and abdominal pain. The amylase in the pleural fluid as well as the serum was ultimately characterized as a macroamylase on electrophoresis and chromatography. A diagnosis of lymphoma subsequently became obvious. The pathogenesis of the macroamylase in the pleural effusion and the association of macroamylasemia with malignant disease is discussed.

Amylases↗
PubMed1983

Comparison of electrophoretic isoamylase patterns among various species.

The electrophoretic pattern of isoamylase in the serum, urine, pancreas, salivary gland, liver, and small intestine of the dog, pig, rat, hamster, and prairie dog was compared to man. Great species variation in isoamylase patterns was noted. These variations should be kept in mind when studying pancreatic disease in species other than man. It is of interest that the serum and urine isoamylase of the prairie dog was most similar to that of man.

Amylases↗
PubMed1983

Acquired angiodysplasia as a cause of gastric hemorrhage: a possible consequence of cholesterol embolization.

A patient with aortic stenosis and gastrointestinal bleeding due to angiodysplastic (telangiectatic) lesions in the stomach is presented. Biopsy of the lesions showed cholesterol emboli with granuloma formation, intramucosal vascular obstruction, subepithelial ectatic vessels, and epithelial atrophy. The case history appeared to indicate the formation of new lesions over time and a tendency to a regression of some of the least advanced lesions. It is suggested that cholesterol showers from the aortic valve or atheromatous aortic plaques may be one cause of acquired angiodysplastic lesions in the gastrointestinal tract.

Aged↗
PubMed1983

Pancreatitis associated with duodenal Crohn's disease.

The fourth reported patient with acute pancreatitis associated with Crohn's disease of the duodenum is presented and the clinical features compared with previously described cases. The pathogenesis of the pancreatitis was not clear but the inflammatory process was found to involve the ampulla of Vater making ampullary incompetence with duodenal reflux or ampullary obstruction the most likely mechanisms. High dose prednisone combined with nasogastric suction and subsequently long-term Cimetidine resulted in a rapid improvement which has been maintained.

Adult↗
PubMed1982

Percutaneous ultrasound-guided puncture of the gallbladder (PUPG).

Percutaneous ultrasound-guided puncture of the gallbladder (PUPG) is a new method for antegrade study of the gallbladder and the common bile duct. All procedures were scheduled immediately prior to planned surgery. Under ultrasound guidance, a 22-gauge sheathed needle was placed into the gallbladder lumen, and dilute (25% to 30%) diatrizoate meglumine (Hypaque) was injected. Indications in five patients included: evaluation of the common bile duct for calculi and/or obstruction, specifically in one patient who had hypersensitivity to intravenous contrast material; aspiration of bile for gram stain, crystal analysis, and cytology; evaluation of the gallbladder lumen for intraluminal masses; and to establish the anatomic site of an occult abscess. A small bile leak occurred in one patient who had no obstruction, and a more significant leak occurred in a patient who had obstructive jaundice and ampullary carcinoma. PUPG obviated the need for surgical intervention in three patients. Although the method has limited indications, we feel that it has great diagnostic potential in conditions related to the gallbladder and biliary ducts.

Adult↗
PubMed1981

In pursuit of sisterhood: adult siblings as a resource for combined individual and family therapy.

Therapists traditionally view brothers and sisters as rivalrous and self-seeking. Under carefully arranged conditions, however, siblings can learn to cooperate with each other to resolve important conflicts in family relationships. This case documents a dramatic change in the relationship between a 29-year-old woman and her father, the outcome of a three-step therapeutic intervention in which sibling dynamics were selectively used by the psychotherapist. As part of her individual therapy, the therapist first aroused the woman's discontent with her status as the neglected "baby of the family." Next, a series of meetings were held with the woman and her three sisters that permitted resolution of their previous anger and misunderstandings, thus helping them to become a more cohesive group of sisters. The third step brought the sisters, now as allies both of the identified patient and of the therapist, into a constructive confrontation with the parents. This resulted in lasting personal change for the identified patient and improved relationships throughout the entire family.

Adult↗
PubMed1980

The long-term effects of vagotomy and drainage, parietal cell vagotomy and H2 receptor antagonists on duodenal ulcers and gastric function and structure.

This paper presents a comparative retrospective analysis of the effects of vagotomy and drainage, parietal cell vagotomy (PVC) and maintenance H2 receptor antagonist (H2RA) therapy on ulcer recurrence rates, clinical status, gastric acid secretion, serum gastrin responses and gastric structure in the elective treatment of duodenal ulcer. The results indicate that the operations offered greater protection against recurrent ulceration, and that H2RA therapy provides some protection against recurrence while the patient is on continued treatment but does not alter the natural history of the disease when treatment is stopped. The evidence to date suggests that neither PCV nor H2RA therapy has altered the conventional indications for surgical treatment in duodenal ulceration.

Drainage↗
PubMed1980

The prognosis of alcohol-induced calcific pancreatitis.

A consecutive personal series of 314 patients with alcohol-induced calcific pancreatitis were admitted to a long-term follow-up study between 1959 and 1979. The patients were subdivided into four arbitrary groups according to the date of entry into study, and the mortality rate and survivor status were determined for each of these groups. Adjusted mortality rates increased progressively with the duration of follow-up, from 11% in the 1976-1979 to 73% in the 1959-1969 group. Pancreatic insufficiency dominated in patients followed up for 10 - 20 years, and pain was more prominent in the more recent follow-up groups. The survivor status in Whites was better than in Blacks, but the mortality rates were comparable. The occurrence of pain in patients who continued to drink was significantly less in the 10 - 20 year follow-up group than in those followed up for a shorter period of time.

Adult↗