Search PubMed⌕ Search

Biomedical subjects

S Arita

Publications and source records attributed to S Arita.

At least 91 records · Page 5Linked to original sources
PubMed1989

[Predicting recovery of ambulatory function after hypertensive putaminal hemorrhage by multivariate analysis of acute-phase clinical data].

In 66 patients with hypertensive putaminal hemorrhage, several acute-phase clinical parameters were subjected to multivariate analysis and the usefulness of such analysis in predicting the eventual recovery of ambulatory function was evaluated. Seven items were studied: age, laterality of the lesion, computed tomography classification, hematoma volume, level of consciousness on admission, severity of motor impairment of the affected leg on admission, and the treatment employed. A numerical prediction of ambulatory function was derived from an equation in which each item was scored and weighted. This value was compared with that of the actual ambulatory ability several months after onset, as rated on a 5-point scale. In these 66 cases, the predicted and actual outcomes were well correlated (r = 0.871). The results indicate that an accurate prognosis can be made on the basis of clinical data obtained in the acute phase of putaminal hemorrhage.

Acute Disease↗
PubMed1989

The thallium-201 time activity curve in thyroid cancer: a role for the detection of metastases.

The Tl-201 Cl time activity curves were evaluated in 17 patients with histologically proven benign nodules and papillary carcinoma of the thyroid gland. In the dynamic studies, the uptake at the region of interest was counted every 10 sec for 20 min after the intravenous injection of 2mCi Tl-201 Cl. The curves from frame 21 to 100 were transformed to linear plots for clinical evaluation. Papillary carcinoma could not be differentiated from benign lesions by means of the values of the washout rate. However, the "relative washout rate" in papillary carcinoma was lower than that of benign lesions (P less than 0.05). Although the average values of the "relative extrapolated uptake" in papillary carcinoma appeared to be greater than those in benign lesions, the difference was not statistically significant. The difference in the washout rates between lymph node metastases and local recurrences, and pulmonary metastases of the papillary carcinoma was significant (P less than 0.05).

Adenoma↗
PubMed1989

[A study on the inhibition of non-specific neutral proteinase by gold salt. Part 1. Gold sodium thiomalate].

The inhibitory effect of gold sodium thiomalate on non-specific neutral proteinase (EC 3.4.24.4) was investigated in vitro, in order to clarify the suppressive mechanism of the inflammatory process of joints by gold salt. The neutral proteinase was inhibited time- and concentration-dependently by gold salt. When the enzyme was incubated with 1 x 10(-2)M gold sodium thiomalate for 60 minutes, almost 100% of the activity was lost. Even at a lower concentration (1 x 10(-5)M, gold sodium thiomalate inhibited the enzyme time-dependently after longer incubation (3 or 9 hours). However, the same concentration of gold sodium thiomalate previously incubated with alpha-casein did not inhibit it. The results obtained here suggest that gold sodium thiomalate may inhibit the enzyme by binding it. The delay of neutral proteinase inhibition by gold sodium thiomalate seemed to be dependent on the concentration of gold salt.

Antirheumatic Agents↗
PubMed1988

Lung cancer metastasis to adrenocortical adenomas. A chance occurrence or a predilected phenomenon?

To evaluate the common belief that cancer metastasis to adrenocortical adenomas is a predilected phenomenon, we compared the real incidence of cancer metastasis obtained by analyzing the autopsy results of our 160 lung cancer cases, as well as those found by reviewing the literature, with the theoretical incidence obtained through the simulation models we made. The results disclosed that statistically, the real incidence was significantly higher than the theoretical probability. Therefore, we concluded that the metastasis of lung carcinoma to adrenocortical adenomas is indeed predilected.

Adenocarcinoma↗
PubMed1988

[A fatal case of skin cancer 18 years after cadaveric donor renal transplantation].

A 39 years old man was admitted with chronic renal failure, and in June, 1968, he received renal transplantation from a cadaveric donor, 30 years old male, died from cerebral contusion. The graft had been well functioning for 18 years, and he had been engaged in his occupation. At the age of fifty-seven skin cancer (squamous cell carcinoma) occurred in his face, and surgical treatment was carried out. But it metastasized to left parotid, bilateral lungs and other areas of skin, and he died in October 1986, complicated by cerebral infarction. Some reports mention that the incidence of malignancies in posttransplant patients is greater than in general population. Our study reveals that immunological surveillance is weakened in posttransplant patients because of decrease of NK activity, but that the incidence of malignancies (male 0.78%, female 0.45%) is not so great as that reported. There is need of further investigation in this problem.

Adult↗
PubMed1987

A case of multiple simple bone cysts. With special reference to their etiology and treatment.

We report a case of multiple, simple bone cysts in long tubular, short tubular, and flat bones. The internal pressure of the cysts and the oxygen tension of cyst fluid were measured simultaneously. These values were similar to those of typical solitary cysts in other patients. Curettage and bone graft onto the calcaneal cyst were effective, although steroid injection therapy into the metacarpal cyst had no effect. Piercing the ulnar and radial cysts a number of times was uniformly effective. These results may suggest that venous obstruction of the lesions play an important role in the etiology of multiple simple cysts, as shown in typical bone cysts. However, we could not exclude the possibility that simple bone cysts, solitary or multiple, represent some kind of secondary forms of other disorders, or that a simple bone cyst is a heterogeneous entity.

Adult↗
PubMed1986

Radiological evidence of healing of a simple bone cyst after hole drilling.

We report the long-term results with ten patients with simple bone cysts with special retrospective reference to the radiographic evidence of healing after hole drilling. Cortical thickening was initially observed within 3 months, and minimal new bone formation around Kirschner wires left in situ was observed within 4 months. New bone formation gradually progressed from the cyst wall and around the wire. Consolidation of a cyst cavity was uniformly observed 6-7 months after drilling. In several patients residual cysts were seen between the wire and cortical shell. In younger patients, a cystic cavity reappeared after extraction of the wire, although complete radiographic healing had been observed. These findings suggest that a Kirschner wire plays an important role in preventing relapse of simple bone cysts after hole drilling.

Adolescent↗