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Biomedical subjects

S Arima

Publications and source records attributed to S Arima.

At least 145 records · Page 8Linked to original sources
PubMed1981

An unusual case of localized multiple peptic ulcer of the gastric fundus producing a large exophytic fibrous pseudotumor.

We report an unusual case of fundic ulcer of the stomach, suspected radiologically of being an intramural malignant tumor. Grossly the lesion was a protruding large fibrous pseudotumor, reminiscent of fibromatosis or of a granuloma with secondary ulceration. Microscopical examination revealed that it was an unusually voluminous fibrosis produced in the base of long-standing multiple peptic ulcers in a limited area of the gastric fundus. The fundic gland area is a rare site of peptic ulceration, and the occurrence of such an exophytic tumor-forming type of peptic ulcer in this area even rarer, only one relevant case having been reported before.

Female↗
PubMed1981

A lithium and carbamazepine combination in the treatment of bipolar disorder--a preliminary report.

A lithium and carbamazepine combination was reported in five patients with bipolar disorder (DSM-III), who had not received benefits from conventional treatments. Patients 1, 2 and 4 showed favorable antimanic responses to carbamazepine used in combination with lithium carbonate. Patient 3 did not respond well to either lithium or carbamazepine alone, but improved dramatically on the simultaneous administration of the two drugs. The prophylactic benefit was observed in two patients. These clinical results suggest that a lithium and carbamazepine combination may be more efficacious in the treatment of acute manic episode and the prevention of affective recurrences than each drug alone.

Adult↗
PubMed1980

A sedimentation equilibrium study of the temperature-dependent association of bovine beta-casein.

The temperature-dependent association of beta-casein was studied by the sedimentation equilibrium method. The weight-average molecular weight of the protein was determined in 0.2 M sodium phosphate buffer (pH 6.7) at 20, 15, 10 and 2 degrees C, and was found to be dependent markedly on both temperature and protein concentration. The data were well fitted by a monomer-n-mer association scheme, and the values of n, the second viral coefficient, and the free energy change for the association (association constant) were evaluated. The results show that temperature not only shifts the equilibrium but alters the polymer size: the values of n are 49, 22, and 12 at 20, 15, and 10 degrees C, respectively; the free energy change per monomer becomes more negative with increasing temperature, indicating that the attraction between the monomers in a polymer is stronger at higher temperature. This effect of temperature is in contrast to that of ionic strength which affects mainly the equilibrium. The enthalpy change, entropy change, and heat capacity change for the association were also estimated and were indicative of the formation of a considerable amount of hydrophobic bonds upon association.

Caseins↗
PubMed1979

Structure of beta-casein.

The temperature and concentration dependent association of beta-casein was studied by means of viscometry, gel filtration chromatography, electron microscopy, analytical ultracentrifugation and UV difference spectrophotometry. Degrees of polymerization of 12, 22 and 49 and free energies of association of -21, -23 and -25kJ/mole monomer were found at temperatures of 10, 15 and 20 degrees C respectively in 0.2 M Na phosphate buffer pH 6.7. Monomeric beta-casein was not a completely random coil but became more compact with increasing temperature, due to hydrophobic interactions.

Calorimetry↗
PubMed1978

Clinicopathological study on 100 early gastric cancer cases.

Clinicopathological study was given to 100 early gastric cancer cases. The cases included 50 intramucosal lesions (m-group) and 62 submucosal lesions (sm-group), and the share is 17% of whole cases treated surgically. The sex ratio is about 2:1 (male : female). According to the classification by location, the occurrence rate of lesion on anterior wall is 18.8%. This fact suggests the impotance of roentgenscopy by compression technique and double contrast in a prone position focussed on anterior wall. In addition, endoscopy is essential in order to detect minute cancers. The rates of metastasis of early gastric cancers is 2.4% of m-group and 16.1% of sm-group. No metastasis occurs in protruded or elevated type as far as cancer cells remain within the mucosa. Once cancer cells infiltrate into the submucosa, metastasis is observed in 36%. In the present cases, 9 (9%) out of 100 cases of early gastric cancers are the multiple cases. In order to avoid oversight of cancer foci, the portion of stomach to be remained after surgery should be throughly examined prior to operation and again under direct vision after gastric incision.

Adenocarcinoma↗
PubMed1978

Visual evoked potential characteristics and subtypes of schizophrenia.

Visual evoked potentials (VEPs) were recorded from the midoccipital area of 72 schizophrenic patients. The amplitude of wave VI (100- to 115-millisecond latency) was reduced after the addition test for 15 minutes. It recovered to the pretest level later, and four types of recovery curves were found; marked reduction in amplitude occurred in A1 (A1 type), in A3 with fast recovery (A3f type), in A3 with slow recovery (A3s type), and in A5 (A5 type) (A1, A3, A5: averaged potentials evoked by 1-Hz flashes which started 1 minute, 3 minutes, and 5 minutes after the end of the test). Each type closely corresponded to paranoid, atypical hebephrenic, typical hebephrenic, and simple schizophrenia, respectively.

Electroencephalography↗