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Biomedical subjects

S A Shalaev

Publications and source records attributed to S A Shalaev.

At least 37 records · Page 2Linked to original sources

[Disorders of erythrocyte deformability in patients with acute suppurative-septic diseases of the lung and pleura].

In 163 patients with acute suppurations of lungs and pleura a substantial reduction of deformability of erythrocytes was established. The maximum increased rigidity of blood red cells was noted at the peak of the pyo-destructive process and postoperative period as well as in the complicated course of the postoperative period. The curative plasmapheresis, general hyperbaric oxygenation exert positive influence upon plastic properties of erythrocytes.

Acute Disease↗

[Possibilities of reconstruction of the fingers in relation to individual differences in their topographic-anatomic structure].

On the basis of the results of topographic and anatomical investigation carried out at 44 hands of cadavers are discussed the possibilities of restoration of the first finger by means of movement of damaged fingers on the neurovascular limb. The fundamental methods of surgical technique, developed with regard to the structure of neurovascular formations of the hand and individual variability of their topography, are expounded.

Cadaver↗

[Leukocyte transfusion in complex treatment of acute pulmonary suppurations].

The authors studied the effect of transfusions of a leukocyte suspension on the main clinico-immunological values of homeostasis in 56 patients with acute pyodestructive diseases of the lungs. They found that inclusion of leukocyte transfusions in the complex of therapeutic measures produced a marked clinical effect, reduced the term of treatment, and allowed successful control of endotoxicosis and immunodeficiency in patients with pulmonary suppuration. Immune leukocytes obtained according to a specially developed method had a more marked immunocorrective effect.

Acute Disease↗

[Donor tissue source in plastic surgery of the hand].

From topographic and anatomical examination of 32 upper limbs the authors proved that an island skin-fascia graft supplied with blood by the septocutaneous branches of the posterior interosseous vascular bundle can be formed on the posterior aspect of the forearm. Such a graft on a peripheral vascular pedicle was transplanted in 6 patients with defects in the integumentary tissues of the hand; it healed completely in 4 cases, peripheral necrosis occurred in 2 cases but did not affect the end result. The use of means of optic magnification and prevention of compression of the vascular pedicle in the postoperative period ensure successful transplantation of the graft.

Adult↗

[The first experience with crural plastic surgery using island composite skin flaps].

An analysis of literature data, topographo-anatomical studies of 23 lower extremities and an experience with using 18 island fasciocutaneous flaps of the lower leg are presented. The article describes the possibilities of using a new donor area for plasty of limited defects of the lower leg and foot after various traumas and their sequelae.

Amputation Stumps↗

[Variants of microsurgical autologous transplantation of composite skin flaps from the external surface of the hip].

Topographic anatomical investigations have established the possibility to make a new complex skin flap on the lateral surface of the femur on the branches of the second perforating artery and vein. The authors propose methods of making a transplant in this field on two vascular pedicles with anastomoses in one of them--a larger one and two separate flaps: a skin-fat and a muscular flaps on a single feeding pedicle. The experimental findings were confirmed by successful clinical observations.

Adipose Tissue↗

[Radiation treatment of postoperative recurrence of lung cancer].

Under study were results of radiation therapy for local recurrent lung cancer after extended and combined resections in 62 out of 960 (6,5 %) of operated patients. The most effective treatment is considered to be radiation therapy for a recurrence under conditions of a usual (by 2 Gr) fractional irradiation up to the total dose of 50-60 Gr. An improvement was obtained in half of the patients. In a third of patients with a local recurrent cancer after operation the life was two years longer than in patients without radiation therapy.

Carcinoma, Squamous Cell↗

[Characteristics of left lung resection for advanced cancer].

Due to the difficulties involved in establishing an early diagnosis, advanced cases make up about 70% of lung cancer patients admitted to specialized surgical wards. According to more than 30 year-old experience gained at the Academy's Hospital Surgical Clinic and evaluation of the end results of extensive and combined resection of the lung for the treatment of cancer, over 26% of cases operated on at the advanced stages of the disease survive for more than 5 years. Special surgical procedures should be carried out in such cases.

Bronchi↗

[Surgical treatment potentials in far-advanced forms of lung cancer].

Until recently the overwhelming number of patients with lung carcinoma admitted for surgical treatment have metasticized forms (stage III) of lung carcinoma. The tumorous process is spread beyond the limits of the injured lung: metastases grow into lymphatic nodes of the mediastinum or into the neighbouring organs and structures of the thoracic cavity. The surgical treatment of such patients is an urgent problem and presents great difficulties. Specific methods for the surgical treatment of patients with stage III lung carcinoma suggest that such operations should be performed in specialized hospitals.

Blood Transfusion, Autologous↗

[Postoperative irradiation in the combined treatment of lung cancer patients].

The end results of surgical and combination therapy of lung cancer are compared on the basis of rates of survival for 5 years and longer. Extended resection of lung including the removal of lymph nodes and mediastinal fat tissue was performed in all cases. Such megavolt radiation sources as Lootch, Rokus, Lu-4, 3 Mev were used in postoperative radiation treatment. No significant differences in the end results of the two schemes of treatment were found in cases of stage I-II tumors. Survival for 5 years and longer were registered in 30.2% of patients with stage III tumor after combination therapy and 25.9% of patients treated by surgery alone. Surgical treatment of extensive stage III tumor should be followed by radiation.

Adenocarcinoma↗

[Immunological reaction to 3-hydroxyanthranilic acid in the diagnosis of lung cancer].

Two hundred patients with carcinoma of lungs, 56 patients with chronic pneumonia and 142 donors were investigated to reveal the presence of 3-hydroxyanthranilic acid antigen in their blood serum. The antigen was found to equal 91,5%, 25% and 1,4% respectively. The pronounced tendency to decrease the response to 3-hydroxyanthranilic acid antigen and to increase the titres of isohemagglutinins was observed in radically operated patients. The opposite tendency was found to develop in incurable patients.

3-Hydroxyanthranilic Acid↗

[Lung cancer metastasis via the intrapulmonary lymphatic collectors].

In 75 patients operated upon for lung cancer a careful histological assay of the removed regional lymph nodes of intrapulmonary, hilar and mediastinal groups was made. It was found that by the moment of surgery 61 patients had lymphogenic metastases. The direction of metastatic spread mainly corresponds to regional lymph outflow from pulmonary lobes. Therefore there is a reasonable involvement of interlobar lymph nodes. The study enabled the determination of boundaries of rational, oncologically substantiated lobar resections of the lung for cancer and the possible extent of surgical intervention on regional lymphatic collectors.

Humans↗