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Biomedical subjects

S A Shalaev

Publications and source records attributed to S A Shalaev.

At least 19 recordsLinked to original sources
PubMed2006

[Surgical treatment of lung cancer complicated by intrathoracic inflammatory paracancrous alterations].

An experience with diagnostics and surgical treatment of 291 patients with complicated course of lung cancer is described with special reference to specificities of the clinical course, preoperative management and operation technique. It was shown that the purposeful preoperative management allowed the assessment of the patients, previously thought to be inoperable, to be revised in 25% of cases, and the frequency of postoperative complications and lethality to be reduced to 14 and 3.5% respectively. The 5 year survival of lung cancer patients with paracancrous alterations was 20.7%.

Carcinoma, Non-Small-Cell Lung↗
PubMed2006

[Diagnosis and treatment of lung cancer associated with paracancerous changes in the thoracic cavity].

Incidence of lung cancer associated with secondary paracancerous changes is known to range 13.7-30%. Since they reveal such clinical symptoms as pneumonia or empyema, most out-patients with complicated cancers are referred to general wards. Inflammatory parenchymal pathology may be conducive to false-positive or -negative diagnosis even when highly-sophisticated radiation procedures are used.

Aged↗
PubMed2005

[One-stage operations on the lungs and other organs in multifocal and metastatic cancer].

Surgical treatment of 135 patients with multifocal and metastatic cancer of the lungs and other organs is analyzed. The absence of absolute differential diagnostic differences between true poly-neoplasia and synchronous or metachronous solitary metastases leads to extension of indications to surgical treatment of these patients. Surgical procedures were performed in 109 patients, 37 (33.9%) of them were one-stage. One-stage procedures meet the requirements of radical surgery and are most preferable biologically and clinically. These surgeries decrease treatment duration, prolong survival to 3-5 and more years in many patients. As cytoreductive operations, one-stage resections improve the condition of the patients, enable effective polychemotherapy.

Adrenal Gland Neoplasms↗
PubMed2005

[Surgical treatment of lung cancer patients with brain metastases].

The authors present an experience with diagnosing and treatment of 16 patients suffering from lung cancer with solitary metastasis into the brain. The examination performed has shown that in 7 out of 16 patients the surgical treatment was found to be not expedient. This solution was based on the detection of an extensive spread of lung cancer: multiple metastasis outside the thoracic cavity and the brain or inside the brain, and in one case--due to a considerable reduction of indices of the functional and reserve capacities of respiration and blood circulation. Single-step operations were carried out in 9 patients with lung cancer with a solitary metastasis into the brain (resection of the lung with an ablation of the brain metastasis). Out of the 9 patients operated on 6 patients survived for as long as 1.5 to 2 years, one patient lived longer than 4 years. Two other patients operated upon in June 2003 and March 2004 are still alive and feel much better. Satisfactory results of treatment of these patients show such methods to be expedient.

Adenocarcinoma↗
PubMed2004

[Surgical treatment of patients with primary-multiple cancer and involvement of the lungs and other organs].

The article presents experiences with diagnosis and treatment of 43 patients with synchronous primary-multiple cancer of the lung with localization of one and more tumors in the lung which makes 4.8% of the number of the examined and treated patients with lung cancer in the clinic of thoracic surgery of the Military Medical Academy during 1995-2003. In 10 patients with primary-multiple cancer the injury of the lungs was combined with a tumor of the gastro-intestinal tract, in 13 with cancer of the urinary system, in 19 patients the synchronously developing tumor was localized in the lungs with a bilateral affection and in 1 case in different lobes of one lung. Surgical operations on 24 patients with primary-multiple cancer with the involvement of lungs were performed at one stage on each of the organs involved. Satisfactory results of treatment of these patients confirm the expedience of such strategy.

Adenocarcinoma↗
PubMed2002

[Lung cancer complicated by paraneoplastic state].

A 10 year experience with dealing with the problem of surgical treatment of patients with lung cancer complicated by paracancrosis is described. Paracancrosis is characterized by the appearance and manifestation of different inflammatory and pyodestructive alterations in the thoracic cavity resulting from the tumor. The paracancrosis pathogenesis, its clinical symptoms, methods of diagnosis are described. The specific features of surgical treatment of patients with lung cancer complicated by paracancrosis are shown as well as the results of 5-year follow-up.

Follow-Up Studies↗
PubMed2001

[Extended and combined operations for lung cancer].

On the basis of classificating components of the TNM system 1720 patients with "later" stages of the development of lung cancer were selected from 3000 patients with this disease operated upon in the clinic for many years. Specific features of performing extended and extended combined operative interventions, treatment at the postoperative period are described and substantiated. After their discharge from the hospital correspondingly 26% and 21.5% of the patients who had the IIIA stage of the disease are alive for more than 5 years, that convinces in expediency of their surgical treatment.

Adult↗
PubMed1999

[Classification of surgical procedures in lung cancer].

Various aspects of classification of surgical operations in cancer of the lung are presented. The authors suggest their supplement and changes in systematization of surgical interventions in malignant tumors of the lungs published by V.I. Chissov et al. (1995). Basing on the study and analysis of many years experience in surgical treatment of patients with advanced stages of lung cancer in the clinic of thoracic surgery of the Military Medical Academy, the authors suggest classification of combined operations which takes into account both a character and an extent of an extrapulmonary spread of the tumors and thus reflects peculiarities and a high degree of traumatism of surgical intervention and allows to approach more differentially to the assessment of initial and long-term results of surgical treatment of patients.

Humans↗
PubMed1995

[The therapeutic procedure in different degrees of leakage in the injured lung].

Based of an experience with treatment of 118 patients with spontaneous and posttraumatic pneumothorax, pyopneumothorax and state after resection of the lung, the authors have developed a method of determination of the degree of nonhermeticity of the lung in different regimens of respiration and of the selection of treatment depending on the nonhermeticity of the lung.

Empyema, Pleural↗
PubMed1993

[Surgical methods in the treatment of gunshot penetrating wounds of the chest].

The authors conducted a comparative analysis of the course of traumatic disease in 1,920 persons with chest injury, according to the character of the injury, the time of surgical aid, and the features of the therapeutic tactics. The surgical tactics consisted mostly in closed active drainage of the pleural cavity (in 52.5%) and surgical debridement of the wounds in the chest wall (in 36.8% of patients). Closure of open pneumothorax and drainage of the pleural cavity was conducted in 27.7% and thoracotomy in 10.6% of the injured. Purulent complications were diagnosed in 21.8% of patients, including pyothorax in 13.8% and suppuration of the chest wound in 6.0% of cases. The duration of in-patient treatment for chest injuries was 36.4 +/- 3.8 days, but increased by 2.5-3 times with the development of purulent complications. The lethality rate among the patients of the analysed group was 16.2%, among which were 1.9% of deaths from severe purulent complications.

Debridement↗
PubMed1992

[Extensive and combined resections in poorly differentiated lung cancer].

The article generalizes an experience with surgical treatment of lung cancer of low-differentiated structures in 108 patients. Extended and combined resections of the lung in such patients were shown to be expedient. From 83 patients who had had bronchial biopsy in the process of preoperative examination 35 patients (42.2%) had results of histological examinations of the biopsy and operative materials which did not coincide. Extended and combined resections for lung cancer of low-differentiated structure gave 5-year survival in 15.6% of the patients.

Adenocarcinoma↗
PubMed1992

[Megakaryocytopoiesis in patients with acute infectious destruction of the lungs].

Partial megakaryocytograms were studied in patients with acute infectious destructions of the lungs. Acid phosphatase and glycogen megakaryocytic levels, overall number of megakaryocytes elucidated the role of the central link of the system megakaryocyte--platelet in the onset of thromboembolism and hemorrhagic complications arising in the above patients. Inefficiency of megakaryocytopoiesis in pulmonary and pleural acute pyo-destructions is under discussion.

Acute Disease↗
PubMed1992

[Penetrating gunshot wounds of the chest: the surgical procedure and treatment times and outcomes].

On the basis of data obtained during the war in Afghanistan the article analyses surgical management and the results of treatment in three groups of patients with chest wounds. The authors consider that the efficiency of treatment could be improved by gaining time during evacuation period and providing the earliest surgical care to the wounded. Indications and peculiarities for various surgical interventions were ascertained depending on the character of trauma and subsequent pathological disorders. The article proves the necessity of preventive sanitation of pleural cavity, gives the data concerning the period and outcome of treatment.

Afghanistan↗