Biomedical subjects

Robert C Waag

Publications and source records attributed to Robert C Waag.

5 recordsLinked to original sources

PubMed2003

Simulation of ultrasonic focus aberration and correction through human tissue.

Ultrasonic focusing in two dimensions has been investigated by calculating the propagation of ultrasonic pulses through cross-sectional models of human abdominal wall and breast. Propagation calculations used a full-wave k-space method that accounts for spatial variations in density, sound speed, and frequency-dependent absorption and includes perfectly matched layer absorbing boundary conditions. To obtain a distorted receive wavefront, propagation from a point source through the tissue path was computed. Receive focusing used an angular spectrum method. Transmit focusing was accomplished by propagating a pressure wavefront from a virtual array through the tissue path. As well as uncompensated focusing, focusing that employed time-shift compensation and time-shift compensation after backpropagation was investigated in both transmit and receive and time reversal was investigated for transmit focusing in addition. The results indicate, consistent with measurements, that breast causes greater focus degradation than abdominal wall. The investigated compensation methods corrected the receive focus better than the transmit focus. Time-shift compensation after backpropagation improved the focus from that obtained using time-shift compensation alone but the improvement was less in transmit focusing than in receive focusing. Transmit focusing by time reversal resulted in lower sidelobes but larger mainlobes than the other investigated transmit focus compensation methods.

Abdomen↗

PubMed2002

Estimation and compensation of ultrasonic wavefront distortion using a blind system identification method.

A common random input filter model is described for estimation and correction of wavefront aberration in ultrasonic b-scan imaging. In the model, aberration between the focus and the transducer elements is represented by the response of a linear filter bank to a common random signal. The response of each filter in the bank is found using a two-level extension of an existing subspace method for blind system identification. The receive waveforms are compensated using an inverse filter, and the transmit waveforms are predistorted using time reversal. To test the model, experiments were conducted using a two-dimensional array system to obtain echoes from a point reflector and from a random medium in each case through an aberrator. The aberrator is a phantom that mimics wavefront distortion produced by human abdominal wall, and the random medium is made to mimic ultrasonic characteristics of human liver. The results indicate the method can improve both the transmit and the receive focus and can outperform time-shift estimation and compensation as well as the method of backpropagation followed by timeshift estimation and compensation.

Abdominal Muscles↗

PubMed2002

Examples of design curves for multirow arrays used with time-shift compensation.

The effect of 1.75-D array element height on time-shift compensation is analyzed using a two-dimensional array system and a distributed aberration phantom. The analysis uses hydrophone measurements of transmit beams. The results indicate that, for imaging at 3 MHz through aberration representative of the abdominal wall, similar focus compensation performance can be expected from arrays with element pitches less than or equal to 3.0 mm.

Phantoms, Imaging↗

PubMed2002

A k-space method for coupled first-order acoustic propagation equations.

A k-space method for large-scale simulation of ultrasonic pulse propagation is presented. The present method, which solves the coupled first-order differential equations for wave propagation in inhomogeneous media, is derived in a simple form analogous to previous finite-difference methods with staggered spatial and temporal grids. Like k-space methods based on second-order wave equations, the present method is exact for homogeneous media, unconditionally stable for "slow" [c(r) < or = c0] media, and highly accurate for general weakly scattering media. In addition, unlike previous k-space methods, the form of the method allows straightforward inclusion of relaxation absorption and perfectly matched layer (PML) nonreflecting boundary conditions. Numerical examples illustrate the capabilities of the present k-space method. For weakly inhomogeneous media, accurate results are obtained using coarser temporal and spatial steps than possible with comparable finite-difference and pseudospectral methods. The low dispersion of the k-space method allows accurate representation of frequency-dependent attenuation and phase velocity associated with relaxation absorption. A technique for reduction of Gibbs phenomenon artifacts, in which compressibility and exponentially scaled density functions are smoothed by half-band filtering, is introduced. When employed together with this smoothing technique, the k-space method provides high accuracy for media including discontinuities, high-contrast inhomogeneities, and scattering structures smaller than the spatial grid resolution.

Acoustics↗

PubMed2002

Spatial coherence analysis applied to aberration correction using a two-dimensional array system.

Complex degree of coherence functions are computed using synthetic and measured ultrasound data to demonstrate noteworthy aspects of coherence analysis in the context of aberration correction. Coherence functions calculated from synthetic data illustrate the importance of proper normalization of the constituent cross-correlation integrals when weak elements and receiver directivity are significant factors. The synthetic data also show that a spike can occur at the zero-lag position of the coherence function when the signal-to-noise ratio is reduced by element directivity near the edges of a large aperture. The latter observation is confirmed by experimental data acquired through tissue-mimicking distributed aberration phantoms using a low f-number two-dimensional array system. The coherence of data acquired at neighboring elements is not changed by time-shift compensation of transmit and receive focusing, but time-shift compensation does improve the coherence of echoes measured over larger separations. The resulting increase in coherence widths evaluated at levels between 0.2 and 0.5 is correlated with narrower -10 dB and -20 dB effective widths in focuses visualized using single-transmit images. Iterative focus compensation methods may benefit from aberration estimation algorithms that take advantage of these longer-range correlations in random-scattering waveforms.

Artifacts↗