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Biomedical subjects

R Voigt

Publications and source records attributed to R Voigt.

At least 199 records · Page 11Linked to original sources

[Clinical studies on the connection between preceding abruptio placentae and abortus and subsequent complications during the afterbirth phase (author's transl)].

2176 vaginal deliveries at Jena University Hospital were selected at random to check whether in these patients it is possible to establish the connection postulated by some authors between preceding premature termination of pregnancy and the mass incidence of afterbirth haemorrhages, as well as of necessary surgery in the afterbirth phase. There was no significant increase of afterbirth complications following abruptio placentae and abortus, whereas there are partly statistically significant differences in the incidence of surgery reauired in children of normal weight of underweight.

Abortion, Spontaneous↗

[Clinical studies on acidosis morbidity (author's transl)].

Basing on the pH values of the umbilical artery of a total of 3,421 births in 1977 and in the first half of 1978, the acidosis morbidity associated with the various methods of delivery and dependent upon the weight at birth is determined, and compared with the Apgar score. The results are discussed with reference to literature. It is concluded from this study that electronic monitoring should be intensified, that indication for abdominal Caesarean section should be considered on a relatively liberal scale, and that the quota of underweight children should be reduced further.

Acidosis, Respiratory↗

[Clinical studies on the effect of pregnancy and labor on the pharmacokinetics of ampicillin].

After giving 5 g Ampicillin intravenously to a total of 33 women (gravidae during the VIII. month pregnancy, women in labor and health controll persons) the serum levels of the mothers were analysed according to the pharmacokinetic parameter half-life of elimination.--Our results show that only the delivery cause significant differences of the kinetic of ampicillin.--Our results are discussed with the data given by literature.

Adult↗

[Isotope nephrographic studies during hormonal contraception using Depositon].

By means of isotope nephrograms of a total of 29 renally healthy women who had been taken for more than 1 year the drug Deposiston, the renal function is investigated. Checking is done by using the semiquantitative evaluation parameters according to Zum Winkel, Pabst and Hör and to own criteria. Our results show that the highly dosed application of estrogens does not induce significant changes of renal function in the isotope nephrogram.

Contraceptives, Oral↗

[Possibilities of testing sex steroid effects in the uropoietic system].

Progesterone as the main representative of gestagen-effective sexual steroide does not cause allone a statistically significant dilation of the lumina of the ureters compared with the adequate values of the control urogrammes. The fact that in pregnant rabbits no dilation of the ureters and of the renal pelvis was to be found allows the suspicion that during the pregnancy of the animal species used there are other mechanical conditions than during the human gravidity.

Animals↗

[Experimental investigations on the effect of progesterone on contrast excretion (author's transl)].

The relationship between high dose progesterone treatment and pregnancy and dilatation of the upper urinary tract was investigated by doing intravenous urograms on eight female rabbits. Ten features of the urogram were studied. It was concluded that the administration of sex hormones to rabbits without any mechanical change in the ureters, did not lead to urographically demonstrable dilatation of the ureters. Negative findings in pregnant animals indicate that the mechanical situation in rabbits differs from that found in human pregnancy. The results are discussed with relation to the available literature.

Animals↗

[Sequential scintigraphy in the investigation of changes in renal function during pregnancy (author's transl)].

Changes in renal function during pregnancy were studied by sequential scintigraphy in 16 women with normal kidneys. The examinations were carried out during the first and third trimesters. Time activity curves were obtained by a computer-assisted storage and analysis procedure, using a "region of interest" technique for renal parenchyma and renal pelvis. The study included topographic changes and the evaluation of 13 semi-quantitative parameters related to the renal parenchyma and of nine parameters related to the renal pelvis. The results were demonstrated graphically. The predominantly rightsided changes in renal function during the third trimester are discussed in relation to the relevant literature.

Adolescent↗