Prolonged survival of skin grafts in mice following treatment of the donors with fractions of cell-free Ehrlich ascites fluid.
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Biomedical subjects
Publications and source records attributed to R Udassin.
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Serum glucose and lactic acid levels were determined in 20 young volunteers prior to and following marches with increasing back pack loads (30 and 35 kg) and distances (6 and 12 km). The drop in serum glucose levels correlated well with the degree of effort. A significant mean drop in serum glucose level of 10.3 mg% was detected only in the group carrying 35 kg for a distance of 12 km. In this group, objective physiological parameters as well as subjective grading of the march's difficulty indicated the effort to be strenuous. Serum lactic acid level did not change significantly following any march. Serum glucose level may serve an indicator for determination of work's duration and intensity, determination of optimal distances for untrained hikers and of optimal loads to be carried for various distances.
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A 2 1/2-year-old female is reported with ring 18 chromosome syndrome. The chromosomal abnormality was found in all examined leukocytes and cultured skin fibroblasts. Besides the usual clinical characteristics of this syndrome, two additional features are described that have not been reported previously: right hemidysmorphism, including hypertrophy of the tongue and lower extremity; coloboma of the lower right side of the gums; atretic external right ear canal; and hypotonia with mitochondrial encephalomyopathy associated with excessive ketonemia during normal food intake and a large increase after overnight fast.
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The aim of this study was to determine the contribution of intestinal motility and cecal bacterial overgrowth to liquid diet-induced bacterial translocation (BT). Three different commercially available liquid diets were offered to mice for 1 week. BT to the mesenteric lymph nodes (MLN), spleen, and liver were examined as well as cecal bacterial counts and populations, small bowel length and weight, and histopathologic changes in the ileal and jejunal mucosa. In addition, the effect of the various diets on intestinal motility was measured by the transit index of a charcoal mixture introduced into the stomach. The incidence of BT to the mesenteric lymph nodes was significantly and similarly increased (p < .05) in mice fed Vivonex (30%), Ensure (30%), and Osmolite (33%) compared with chow-fed controls (0%). Compared with chow-fed controls, all three liquid diets were associated with the development of cecal bacterial overgrowth (p < .01). There were no significant changes in the transit index for the three liquid diet groups compared with the chow-fed controls. BT to the MLN was induced by all three liquid diets tested, casting some doubts as to their role in preventing BT in clinical use. BT was associated with a statistically significant increase in cecal bacterial count but was not associated with gut motility changes in this model. In fact, no significant changes in intestinal motility were noted in all groups tested.