Search PubMed⌕ Search

Biomedical subjects

R Terinde

Publications and source records attributed to R Terinde.

At least 73 records · Page 4Linked to original sources
PubMed1986

[Changes in the diagnosis and therapy of extrauterine pregnancy with special emphasis on ultrasound. Study at the Gynecologic Clinic of the Düsseldorf University, 1962-1983].

The diagnosis and therapy of ectopic pregnancy underwent a change with the introduction of ultrasound and the sensitive beta-hCG test. The modified management of ectopic pregnancy at the Department of Gynaecology of the University of Düsseldorf was analysed by examining the case history of 938 patients with suspected ectopic pregnancy from 1962-1983. The diagnosis ectopic pregnancy was confirmed for 348 patients (37%), whereas it was excluded in 590 cases (63%). The Pregnosticon test and the Gonavislide test yielded positive results in only little more than half of the cases with ectopic pregnancy. The Neo-Pregnosticon test was positive for 13 out of 15 patients. There was no ectopic pregnancy with a negative beta-hCG test (n = 31). Out of 261 patients examined by ultrasound, an ectopic pregnancy was proved directly four times. Sonographic pointers to an ectopic pregnancy were found with equal frequency in patients with confirmed ectopic pregnancy and in patients with excluded ectopic pregnancy (79%). In 17% of the patients with confirmed ectopic pregnancy this could not be detected by ultrasound. Out of 92 patients who had an ultrasound examination and a beta-hCG test, an intrauterine pregnancy could be excluded in spite of a positive pregnancy test in 94% of the ectopic pregnancies (n = 31) and in 31% of the cases with excluded ectopic pregnancy (n = 61). The incidence rate of ruptured tubule pregnancy was 44% before the introduction of ultrasound in 1973; it dropped subsequently to 37%. Since the introduction of the beta-hCG test in 1981 the incidence dropped further to 21%.(ABSTRACT TRUNCATED AT 250 WORDS)

Diagnosis, Differential↗
PubMed1985

The value of ovarian and placental steroid determinations in abnormal early pregnancy.

Concentrations of estradiol (E2), progesterone (P), and 170H-progesterone (170H-P) were measured by radioimmunoassay in serum samples obtained from a group of 98 women with threatened (n = 60), incomplete (n = 22) or missed (n = 16) abortion between the 4th and 17th week of pregnancy. The diagnosis was based on the clinical symptoms and the results of ultrasound scanning. In threatened abortion 54, out of 60 E2 values were within the 95% normal range, including most of the cases in which abortion occurred later. In incomplete abortion 18 of 21 E2 values were below the lower 95% confidence limit. In missed abortion, 11 of 15 E2 values were abnormal, being below the 95% normal range. Similar patterns in women with threatened, incomplete or missed abortion can be observed for values of P and 170H-P. Our results indicate that serum determinations of ovarian and placental steroids in women with early pregnancy failure are not of great clinical value.

17-alpha-Hydroxyprogesterone↗
PubMed1981

Serum levels of oestradiol-15 beta and luteinizing hormone related to follicular growth as monitored by ultrasound in women with normal menstrual cycles.

Serum levels of oestradiol-15 beta (Oe2), luteinizing hormone (LH) and progesterone (P) in 20 healthy women were correlated to the size of the ripening follicle during the follicular phase of normal menstrual cycles. Growing follicles were measured by ultrasound using the full bladder technique. In each individual case a good correlation (r = 0.88) between the Oe2 values and the size of the maturing follicle was found. However, since all women examined ovulated at a different Graafian follicle diameter (range 17 to 26 mm), the corresponding Oe2 values showed quite a large variation (range 0.78 to 2.5 nmol/l). The cervical score correlated to follicular maturation up to a follicle size of 19 mm (maximal cervical reaction). From there on no further improvement of the cervical parameters could be observed. We conclude that ultrasound monitoring of follicular growth can be a useful addition to the Oe2 and P measurements in the clinical management of the infertile woman. Bifollicular maturation can be diagnosed early, when the endocrinological data are combined with follicle size. Moreover, a correlation can be made between follicular growth and oestradiol production in the individual cycle.

Adult↗
PubMed1980

[Twin pregnancy, one fetus with Down syndrome removed by sectio parva, the other delivered mature and healthy (author's transl)].

We report about a twin pregnancy with trisomy 21 in one of the fetus and normal caryotype of the other one. The affected fetus was removed by sectio parva in the 22nd week of gestation (p. m.) while the placenta remained inside the uterus. At the end of the 38th week of gestation a mature healthy baby was delivered by caesarean section. This was only possible by knowing the exact position of the fetus, placentas and amnion cavities by ultrasound. It is necessary to be familiar with betamimetics for tocolysis used during and after surgery.

Abortion, Legal↗
PubMed1979

[Ultrasonographic diagnosis in disturbances of early pregnancy (author's transl)].

Ultrasonography using high-magnification, modern ultrasonographs enables information on intactness of pregnancy in early disturbed pregnancy. The ultrasound findings can be correlated with the clinical diagnoses, such as incomplete abortion. A final diagnosis, such as missed abortion, can frequently only be made after exact ultrasonographic investigation. The failure rate depends on the equipment and the experience of the investigator. Exact knowledge of the gestational age clearly influences the accuracy of an ultrasonographic diagnosis in early pregnancy. A gestational age earlier than the calculated one may be mistaken for a pregnancy that is no longer intact.

Abortion, Missed↗
PubMed1979

[Prenatal sex determination by radioimmunoassay of testosterone with and without chromatography of the amniotic fluid (author's transl)].

Amniotic fluid testosterone measured by radioimmunoassay (RIA) without chromatography (immunoreactive testosterone) seems not to be a definitive test for prenatal sex determination in all cases. In this study testosterone (T) levels measured by RIA with chromatography of the amniotic fluid samples were compared with immunoreactive testosterone (iT) values, to determine the predictive accuracy of the two methods. In 111 amniotic fluid samples between 15 and 19 weeks of gestation iT and T were measured parallelly. There are significant differences between iT- and T-means of both sexes (p less than 0.001). 95%-condifence limits of iT-values of the male and female fetuses are largely overlapping. In contrast, the overlap of 95%-confidence limits of the T-values is only minor. The measurement of testosterone with chromatography of the amniotic fluid samples shows for prenatal sex determination in over 90% accuracy. This result is due to the elimination of sex-specific differences in crossreacting steroids within the amniotic fluid of both sexes.

Amniotic Fluid↗
PubMed1978

[Ultrasonographic monitoring of ovarian hyperstimulation by exogenous gonadotropins and subsequent twin-pregnancies (author's transl)].

In contrast to estrogen-monitoring the ultrasonographic monitoring of the ovaries renders possible the estimation of individual follicular growth stimulated by gonadotropins. In two patients suffering from anovulation and additional factors inhibiting fertility, ultrasonographic monitoring was used in order to induce a pregnancy after moderate hyperstimulation nevertheless.

Adult↗