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Biomedical subjects

R Tandon

Publications and source records attributed to R Tandon.

At least 361 records · Page 20Linked to original sources
PubMedDate not supplied

Anomalies associated with the parachute mitral valve: a pathologic analysis of 52 cases.

Fifty-two specimens of heart with parachute mitral valve were reviewed. An associated anomaly was present in all but two patients. In these two patients parachute mitral valve was an isolated anomaly. The associated anomalies were divided into those which form part of the developmental complex described by Shone and associates and other anomalies designated as major anomalies. Normally related great vessels were present in 35 cases, double outlet right ventricle in eight cases, complete transposition in four cases, corrected transposition and single ventricle in two cases each and straddling tricuspid valve in one case. The most common associated anomaly was an interventricular communication occurring in 37 cases. Less common anomalies were an atrial septal defect (18 cases), patent ductus arteriosus (21 cases), complete atrioventricular canal (five cases), right-sided obstructive anomalies (13 cases) and left-sided obstructive anomalies other than those as part of the Shone syndrome (11 cases).

Double Outlet Right Ventricle↗
PubMedDate not supplied

A 5-year follow-up study of hypertension in a rural community.

A follow-up study of hypertension was carried out among adults, in the age group between 25 to 64 years, in a rural population of Gurgaon district, Haryana, five years after an initial community based epidemiological survey of the same population. The progress of 77 out of 98 hypertensives detected at the initial survey could be reassessed. The treatment and severity of hypertension found at the initial survey has been compared with that observed on follow-up. The percentage of cases with blood pressure (BP) controlled on treatment increased from 2.6 percent to 45.4 percent on follow-up. An electrocardiogram could be obtained in 66 out of 77 subjects reexamined and was abnormal in 21 cases (31.8%). The electrocardiographic abnormalities found were: myocardial infarction in one, left ventricular hypertrophy in 5, left ventricular hypertrophy with ischaemic ST-T changes in 6, isolated ST-T abnormalities in 5 and conduction defects or arrhythmias in 4 cases. In a cohort of 1,334 subjects who were normotensive at the initial survey, 19 new cases were detected to have hypertension. The overall annual incidence of hypertension was 2.8/1000 (male: 3.8/1000 and female: 2.4/1000). In these hypertensives, a family history of hypertension was present in 10.5 percent and obesity in 42.1 percent.

Adult↗
PubMedDate not supplied

What is 'desirable' lipid profile.

The lipid profile of subjects with and without coronary heart disease (CHD) was studied in two epidemiological studies conducted in an urban and rural population. The prevalence of CHD was 96.7/1000 in the urban area and 27.1/1000 in the rural area. The lipid levels of the rural population, with an entirely different life style, was significantly lower compared to the urban normal population. The data suggest that if the prevalence of CHD is to be reduced in the urban population, the desirable levels of lipids should be those obtained in the rural normal population rather than the urban, CHD free, population.

Adult↗
PubMedDate not supplied

Pulmonary arterial hypertension in patients with secundum atrial septal defects.

BACKGROUND: Experience in Vellore suggests that pulmonary arterial hypertension develops at an earlier age in Indian patients with secundum atrial defects than it does in westerners. We examined the haemodynamic data on patients with secundum atrial defects to determine whether this was also true in Delhi. METHODS: We analysed the data on 461 patients with secundum atrial defects, grouping them according to their pulmonary (Qp) and systemic (Qs) flow rates as well as the ratio of pulmonary to systemic systolic pressure (Pap/Sap) into 4 groups: [table: see text] RESULTS: There were 8 (2%) patients in group 1, 282 (61%) in group 2, 124 (27%) in group 3, 28 (6%) in group 4a and 19 (4%) in group 4b. Of the 19 patients in group 4b, 6 (1%) were below 20 years of age and 13 (3%) above 20 years. CONCLUSION: Our findings indicate that obstructive pulmonary arterial hypertension does not develop early in patients in Delhi.

Adolescent↗