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Biomedical subjects

R Sharma

Publications and source records attributed to R Sharma.

At least 631 records · Page 35Linked to original sources
PubMed1977

Isatin enzyme interactions. V. Activation of rat liver acid phosphatase.

Influence of Isatin on rat tissue acid phosphatase has been studied. It has an organ-specific effect, the liver enzyme is activated, the brain enzyme is inhibited while those of kidney and intestine are not affected. Isatin activation of the liver enzyme is of mixed type and pH dependent. Rat liver enzyme appears to require intact amino and sulfhydryl groups for activity. Isatin seems to combine with the enzyme through the sulfhydryl group of the latter.

Acid Phosphatase↗
PubMed1977

Vegetables responsible for contact dermatitis of the hands.

Fifty-three patients having contact dermatitis on the fingertips showed positive patch tests with several vegetables the commonest being garlic, onion, tomato, and carrot in that order of frequency. Of several preparations, made from garlic onion, tomato, and carrot, the juices used as such gave the maximum number of positive patch test reactions. Lyophilization of the juices led to false-negative patch tests in some cases. Patch tests in the controls were positive in some cases but these were probably cases of latent hypersensitivity, because some of them, like the patients, showed positive reactions even with the diluted juices. The antigens in garlic and onion were extractable in water, ether, acetone, or alcohol and were also present in the essential oils of these vegetables. Infrared spectra of the essential oils of garlic and onion were similar and showed straight chain acids, esters, and methylene groups. Clinically, there was no suggestion of cross-sensitivity between onion and garlic.

Antigens↗
PubMed1975

Leriche's syndrome.

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Acute Kidney Injury↗
PubMed1972

Metabolic effects of contraceptive steroids. I. Observations of blood lipids.

Semilongitudinal observations on fasting blood sugar, total lipids, cholesterol, phospholipids, triglycerides, nonesterified fatty acids (NEFA), and lipoproteins were carried out on 116 women taking combination type oral contraceptives for 3-42 cycles. The changes observed differed with each constituent. Total lipids showed significant increase throughout the period of observation. Cholesterol and phospholipds showed significant increases after about 12 cycles of administration whereas triglycerides showed an increase after 6 cycles of medication. NEFA showed significant decrease in the 1st-3rd cycles. The alpha and beta lipoprotein ratios showed significant changes after 13-24 cycles of treatment. The general trend of change observed is similar to that reported during pregnancy.

Biology↗