Search PubMed⌕ Search

Biomedical subjects

R Sandyk

Publications and source records attributed to R Sandyk.

At least 379 records · Page 21Linked to original sources
PubMed1985

Sensory symptoms in Parkinson's disease and the opioid system.

Primary sensory symptoms not related to somatic disease, are often experienced by patients with Parkinson's disease. These subjective sensations may either accompany or precede the motor disorder. This paper provides evidence supporting a role for the endogenous opioid system in the pathogenesis of sensory symptoms in Parkinson's disease.

Basal Ganglia↗
PubMed1985

Opioid hypofunction in Parkinson's disease.

Loss of dopaminergic neuronal function has been the most consistent biochemical abnormality found in Parkinson's disease. Hypofunction of other transmitter systems has also been demonstrated in this disease. Recently, an opioid-dopamine link has been demonstrated. This paper provides evidence supporting an opioid system hypofunction in Parkinson's disease.

Acetylcholine↗
PubMed1985

Neuroleptic malignant syndrome and the opioid system.

Neuroleptic malignant syndrome is a rare and potentially fatal condition occurring usually in patients on long-term neuroleptic medication. The pathogenesis of the syndrome is poorly understood, but appears to be related to central dopaminergic dysfunction. Recently, an opioid-dopamine link has been demonstrated. This paper discusses evidence supporting an opioid dysfunction in the pathogenesis of neuroleptic malignant syndrome.

Basal Ganglia Diseases↗