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Biomedical subjects

R Rossi

Publications and source records attributed to R Rossi.

At least 469 records · Page 26Linked to original sources
PubMed1982

[Cardiac insufficiency caused by iatrogenic arteriovenous fistula].

Two cases of iatrogenic arterio-venous fistula complicated by heart failure are described. A 50 year-old woman was admitted to the hospital with congestive heart failure and a questionable diagnosis of congestive cardiomyopathy. A continuous murmur heard over the lumbar spine close to a surgical scar from an intervention on the L4-L5 disc that the patient had undergone six months before, led to the diagnosis of an arterio-venous fistula. Angiography demonstrated a direct communication between the right iliac artery and the right iliac vein. After surgical closure of the fistula normal cardiac function was restored. The second patient (a sixty-year-old woman) had undergone surgical mitral valve replacement with a Hancock bioprosthesis 18 months before the current admission. In the post-operative period the percutaneous insertion of an intravenous line through the left jugular vein had been unsuccessfully attempted. She had mild heart failure which was ascribed to incompetence of the bioprosthetic valve. A continuous murmur in the left supraclavear area suggested the presence of an arterio-venous fistula. Angiography showed a direct communication between the supraclavear branch of the left subclavian artery and the left subclavian vein. The fistula was successfully closed. Both cases confirm the potential harmfulness for the vascular bed of certain surgical interventions and intravascular monitoring techniques. When heart failure of uncertain etiology appears in patients previously submitted to the one of the above mentioned procedures, a careful clinical examination can lead to a correct diagnosis of iatrogenic arterio-venous fistula, whose surgical correction is usually followed by the restoration of a normal cardiac function.

Arteriovenous Fistula↗
PubMed1981

[Fenquizone in the medium term treatment of essential hypertension. Double-blind comparison with chlorthalidone and placebo].

In a double blind study, tolerability and antihypertensive effect of fenquizone were compared with those of chlorthalidone and placebo. In both mild and moderately severe essential hypertension, fenquizone and chlortalidone showed a significant antihypertensive effect; moreover, fenquizone lowered the clinostatic arterial diastolic pressure in a more gradual and continuous way. Differently from chlortalidone, fenquizone had no effects on blood levels of potassium and cholesterol.

Adult↗
PubMed1981

[Hiatal hernia, gastroesophageal reflux and the lower esophageal sphincter. Manometric study with the "rapid pull-through method"].

Data obtained by means of rapid pull-through manometry in cases of hiatal hernia with or without gastro-oesophageal reflux are presented. Particular reference is made to lower oesophageal sphincter pressure in reflux symptomatologies irrespective of the presence of hiatal hernia. A relation between age and lower oesophageal pressure was noted. Hypotonia of the sphincter was observed in younger subjects, whose reflux symptoms are more marked and often unassociated with hiatal hernia. In the patients, sphincter dysfunction appears to be related to an error in the neurohormonal control mechanism of this functional complex. Stress is also laid on the rôle of pull-through manometry in the diagnostic, therapeutic and prognostic approach to diseases of this type.

Adult↗
PubMed1980

Possible indication of breast cancer risk through discriminant functions.

In the Ferrara province of Italy, a screening programme for the detection of breast cancer was initiated in 1965; by 1976, 21,120 women had been examined. The biologic history of the women participating in the program is routinely collected at registration. Several biological variables can be extracted from the history. We used 15 biologic variables in order to construct discriminant functions between women affected by breast cancer and a group of control women. It was found that four variables suffice to separate the group of the women with breast cancer from the control group, although with some degree of uncertainty. The theory was advanced that the individual values of a discriminant function may be associated with the risk of healthy women for developing breast cancer. Data collected after the construction of the discriminant function hint at such an association. We have attempted to calculate a discriminant value for healthy women participating in screening programs, so that those having a discriminant value below a given threshold may be considered at higher risk than those above the threshold. The women in the high-risk group may then be submitted to an appropriate examination schedule.

Adult↗