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Biomedical subjects

R Robert

Publications and source records attributed to R Robert.

At least 181 records · Page 10Linked to original sources
PubMed1983

[Post-traumatic cerebrospinal fluid rhinorrhea and otorrhea disclosing Mondini's syndrome].

A mild head injury could have played a role in the development of post-myringotomy cerebrospinal fluid rhinorrhea and otorrhea in an 18-month-old child with Mondini's syndrome. This notion of trauma may prevent exploration of the site of the fistula when these labyrinthic dysplasias are poorly understood. Once suspected, full radiological examination should precede closure of the gap using an otological approach.

Cerebrospinal Fluid Otorrhea↗
PubMed1982

[Primitive ano-rectal neuralgia. Atypical cases (author's transl)].

In a new statistic concerning 245 cases of primary ano-rectal neuralgia, it can be seen that the schematic classical classification derived from Thaysen, Theile, and Bensaude must be maintained (proctalgia fugax: 45 cases; coccygodynia: 44 cases; ano-rectal neuralgia: 95 cases), partially integrating unusual cases of pruritus ani. Among the 4 principle etiologies, while not underestimating the neuropsychical and intestinal factors (constipation, laxatives), the importance of two other factors must be underlined (the urogenital factor, and particularly, the role of menopause, and important pelvic operations (33 cases) often overestimated; rachidian factors: tendomyositis (Garrigues), pseudoradicular factor. The interest of this study is to show that besides these typical cases (81,7%), a number of atypical cases exist, which have often been under-estimated. These cases can be classified in intermediary (4%), associated (10%), alternating (3,3%) cases, in the course of which the different syndromes replace each other or seem superposed. It must be underlined that the notion of these primitive ano-rectal neuralgias must be inserted in the much larger class of perineal urinary, gynecological or bone and ligament neuralgias. The classification remains opened. An etiopathogenical treatment must be installed, that rejects all regional or surgical aggressive acts when not absolutely necessary, and underlines the importance of massage, internal (levator ani), or external (Maigne's technique, attentive and repeated sessions of rachidian massage).U

Adult↗
PubMed1982

Purification of Toxoplasma gondii suspensions from mice peritoneal exudate.

Purification procedures of Toxoplasma gondii suspensions are described. These methods were designed for the elimination of leucocytes or TG 180 cells. We have been using either gradient centrifugation in Ficoll or gel filtration. In the first case, only leucocytes are eliminated (95% of the initial content). On the other hand, gel filtration allowed the elimination of TG 180 cells. The yield (67% to 98%) depends on the chosen gel (Ultrogel AcA 202 or Sephadex G25 fine), and on the amount of TG 180 cells present before filtration.

Animals↗
PubMed1981

[Contribution of arteriography to the investigation of peripheral nerve tumours (author's transl)].

Based on their personal experience of the use of arteriography in 11 patients, the authors describe the angiographic appearances of both benign and malignant peripheral nerve tumours. They emphasise the reasons for errors, and the criteria enabling the precise nature of the lesion to be determined pre-operatively in the majority of cases. Other contributions supplied by angiography are discussed.

Angiography↗
PubMed1980

[Surgical management of primary peripheral nerve tumours (author's transl)].

A rational approach to the surgical treatment of peripheral nerve tumours can be determined by a knowledge of current concepts concerning their pathology and by clinical and arteriographic preoperative findings, and guided by extemporaneous histological examination results. It can be modified by the presence of metastases or associated phakomatosis.

Extremities↗
PubMed1980

[Intraneural synovial cyst in the peroneal nerve. Case report (author's transl)].

The authors report one case of paralysis of the peroneal nerve due to an intraneural synovial cyst, in connection with the superior tibio-fibular joint. After an anatomic work and a complete revue of the literature, etiopathogenic and diagnostic problems seem to be resolved, and this justifies their terminologic choice.

Adult↗
PubMed1976

[Diagnosis of toxoplasmosis by indirect hemagglutination. II. Value of mixed total antigen fixation in the presence of glutaraldehyde in the early diagnosis of the disease].

2640 sera were titered simultaneously with IHA and IFAT. The results obtained show a good correlation between the two technics used. The IHA test seems particularly useful in IgM detection and, according to the mode of operation, is able to detect lower titers of anti-toxoplasma antibodies than in the case of IFAT.

Antibodies↗
PubMed1976

[Diagnosis of toxoplasmosis by indirect hemagglutination. I. Comparative study of fixation of glutaraldehyde on formolized erythrocytes of a soluble endogenous antigen, and insoluble particulate antigen and a total antigen].

Three different sorts of antigen are prepared ultrasonically: a soluble endogenous antigen, an insoluble particular antigen and a total mixed antigen. Formolinized red blood cells are sensibilized with glutaraldehyde. The authors study the sensitivity of the suspensions as a function of the different modes of antigen preparation. The results are compared with those obtained by immunofluorescence. The authors show the usefulness of total ultrasonic antigen which provides suspensions of great sensitivity easily and economically prepared.

Animals↗
PubMedDate not supplied

Evidence for the lectin nature of some dermatophyte haemagglutinins.

Several isolates of dermatophytes covering 13 different species were studied for their haemagglutination activity with erythrocytes of different origins (human, bovine, sheep, mouse and rabbit). The best results were obtained with rabbit erythrocytes. The specific haemagglutination activity of the fungal soluble extracts seemed to be closely related to the ecology of the fungi. Among the different carbohydrate (ose, polyol, osamine) and glycoprotein solutions used in the inhibition experiments, only N-acetyl-neuraminic acid and a sialoglycoprotein, the bovine submaxillary mucin (mucin type 1), showed an inhibiting activity, demonstrating the lectin nature of the haemagglutinins and the importance of sialic acids in the recognition process. Reduction of haemagglutination activity by pretreatment of rabbit erythrocytes with trypsin or neuraminidase solutions further supports this view.

Animals↗
PubMedDate not supplied

Immunocytochemical localization of in vitro binding of human fibrinogen to Candida albicans germ tube and mycelium.

In vitro fixation of human fibrinogen to different morphological stages of Candida albicans was examined immunocytochemically. When detected by fibrinogen latex microspheres or gold particles by scanning electron microscopy, fibrinogen-binding sites were found on the surface of germ tubes and mycelium, but not on blastospores. With transmission electron microscopy, fibrinogen-binding sites appeared associated with the flocculent surface layer, and increased during growth of germ tubes. Prefixation of C. albicans with formaldehyde decreased binding of fibrinogen, and pretreatment with mercaptoethanol and pronase abolished it. On thin sections of low temperature "Lowicryl K4M" -embedded organisms, gold particles were arranged in the form of clusters which extended from the surface through the cell wall. In contrast, the inner cell wall layers were weakly labelled. Labelling was also detected in the cytoplasm of germ tube, suggesting that fibrinogen receptors were synthesized during germ tube formation. In view of the importance of filamentous forms in host tissue adherence and colonization, the role of fibrinogen as a ligand for binding of C. albicans to epithelial cells was postulated.

Binding Sites↗