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Biomedical subjects

R Rath

Publications and source records attributed to R Rath.

At least 19 recordsLinked to original sources
PubMed1990

Severe hemolysis after incomplete mitral valve repair.

We report 2 cases of severe intravascular hemolysis after mitral valve repair using a Duran annuloplasty ring. In both patients residual mitral regurgitation was present, hemolysis was severe enough to warrant a second operation, and hemolysis ceased immediately after the second operation. We believe that a high-velocity regurgitant jet directed toward the cloth-covered annuloplasty ring was responsible for the hemolysis in both patients.

Adult↗
PubMed1990

[Weight reduction in obese patients in the early period after myocardial infarct].

During the early rehabilitation stage to 27 obese subjects after a non-complicated myocardial infarction a low energy diet was administered (2 and 5 MJ resp.--19 patients) or diet no. 7 or 9 (9 and 6 MJ--8 patients). The regime was started on average 8.4 days (at least 5 days) after the acute attack, its tolerance was satisfactory, there were no complications. In the group with a markedly low energy diet the cholesterol and total lipid levels declined. The body weight declined in both groups. It was revealed that early body weight reduction in obese subjects with non-complicated myocardial infarction involves no risk and the hospitalization period can be effectively used also as introduction to the regime in secondary prevention of ischaemic heart disease.

Diet, Reducing↗
PubMed1989

[The present state and perspectives of postgraduate education of physicians in internal medicine].

Postgraduate training in internal medicine, although conceived as a programme for the entire productive life, is most intensive during the preparation for specialization examinations in the discipline. These examinations have two grades. Grade I can be obtained after attendance of a prescribed training and grade II after another four years. The author gives an account of the existing opportunities for training for specialization I in internal medicine (supplementary courses are organized in some regions) and grade II for which the Institute for Postgraduate Medical Training organizes three-month courses in Prague. In these courses not only the acquisition of recent findings is emphasized but also active participation of the participants of the course (demonstrations of patients and lectures prepared on a given subjects). The authors discusses also the possible motivations for postgraduate training after specialization in the discipline of internal medicine. Knowledge of internal medicine is important also for the discipline of general medicine. The author submits some suggestions for collaboration of the two disciplines to achieve a better standard of provided care.

Czechoslovakia↗
PubMed1987

Stress during the postgradual specialty examinations of medical doctors in internal medicine.

The author evaluated the stressing effect of higher grade specialty examinations in internal medicine in 128 doctors who had attended a three-month specialty course. As compared with the control period, in conjunction with the specialty examination the following findings were recorded: a highly significantly increased elimination of adrenaline (to 417%) and noradrenaline (to 342%), a significant increase of both blood pressures (BPs to 111% and BPd to 110%) and of the heart rate (to 123.5%), as to the subjective condition, some sensations--nervousness, insomnia, anxiety, fear etc. with manifestations of "somatization" (e.g. urgency of urination, bowel movements etc.)--were significantly more marked. It was thus revealed that the specialty examination is an important stressing stimulus, psychic manifestations of the stress being more frequent in women as compared with men. It was found that the intensity of stress affects the part of the examination involving tests in writing, while it does not affect the verbal part of the examination.

Adult↗
PubMed1986

Gastrointestinal complications after cardiac surgery.

From 1975 to 1985, a total of 1596 coronary artery bypasses or valve replacements resulted in 18 gastrointestinal tract complications in 16 patients at Good Samaritan Hospital in Cincinnati. Twelve patients were treated surgically (hemorrhagic duodenal ulcer, one patient; perforated duodenal ulcer, one patient; cholecystitis: acalculous, gangrenous, two patients, and calculus, one patient; perforated cecum, one patient; ischemic colitis, one patient; and perforated diverticulitis of the colon, five patients). Six patients were treated conservatively by either nasogastric intubation or nothing by mouth and intravenous therapy (ileus, three patients; acute sigmoid diverticulitis, one patient; and active peptic ulcer disease, two patients). Multisystem failure caused two deaths. The etiology of hollow viscus complications seems to be related to a low-flow state, impairing normal tissue perfusion that can initiate an ischemic change. This change can lead to acute inflammation, perforation, or both or late stricture. When evidence of an acute abdominal disorder is observed or when conservative treatment falls to alleviate symptoms, prompt surgical intervention should be performed.

Aged↗
PubMed1979

Relation to body fat to age in the Czech population.

Density and percentage of fat in the body were investigated in 403 females and 356 males of Czech population using hydrostatic weighing. The group was divided into four age subgroups ranging from 17 through 22, 23 through 29, 30 through 39 and 40 through 49 years. Fat values were found to increase with age, growing in females and males between the ages of 17 to 49 years from 27.1 to 35.4 and from 16.3 to 26%, respectively. In both sexes, the highest difference in the percentage of fat was observed between the second and third decennium. Body weight was also seen to increase with age up to 40 years of age. On the other hand, from 40 through 49 years a decrease in weight was seen both in male and female means, with the body heights also less in older subjects. The values observed, particularly in females, exceed those reported as a rule in other populations. This is accounted for by nutritional factors such as the amount of calories and composition of food and possibly also by the effect of the genetically given somatotype.

Adipose Tissue↗
PubMed1979

Free fatty acid release from human adipose tissue in relation to obesity -- effect of isoprenaline.

The capacity to release non-esterified acids and glycerol from the abdominal subcutaneous adipose tissue into a medium containing different concentrations of isoprenaline was studied in 21 adults with different body weight (14 obese, 7 controls). The obese had a significantly lower maximum adipokinetic capacity (expressed as pD2) than controls. The significant decrease in pD2 in the obese was found to depend on the stabilization of the weight while the dynamic pD2 stage values of the obese did not differ from those of controls. The hypothesis is expressed that lower pD2 values may be related to the smaller decrease of body fat during weight reduction.

Adipose Tissue↗
PubMed1979

The effect of mazindol on metabolic and regulatory changes in obese women during weight reduction.

The effect of mazindol (1 mg/day) on some metabolic and regulatory values was investigated in ten adult obese women and compared with the same number of controls during weight reduction in hospital (a five-times repeated cycle of 5 days complete starvation and 3 days on a 500 kcal(2.1MJ/day diet.) Mazindol caused a rise of hydroxyacyl CoA dehydrogenase in striated muscle by 70 per cent and a marked decline in malic dehydrogenase. Mazindol also produced higher levels of non-esterified fatty acids--significantly higher during the fifth starvation period; a small decrease in blood glucose, IRI and glucose/IRI ratio being unaffected, a significantly two-fold greater decrease of serum cholesterol; a significant increase of the noradrenaline elimination compared with a decrease in controls and in increase in triiodothyronine binding globulin towards the upper range of normal.

Adult↗
PubMed1978

Partial trisomy for the short arm of chromosome 2 due to familial balance translocation.

A partial trisomy for the short arm of chromosome 2 (p21 leads to pter) was observed in a severely retarded infant with facial, skeletal, genital, renal, and CNS anomalies. The phenotypically normal mother and older brother had a balanced translocation between the short arm of chromosome 2 and the long arm of chromosome 14: 46, XX-XY,t(2;14)(p21;q32).

Abnormalities, Multiple↗
PubMed1978

Some recent findings in obesity.

The tendency of some obese subjects to an energy-sparing reaction can be induced temporarily by attempts of the patient to reduce his overweight by prolonged starvation. This regulatory reaction may be induced by regulatory especially thyroid mechanisms. In obesity of both sexes a tendency to anaerobic energy utilization in the muscle can be revealed and so a tendency to decrease energy utilization in general. The differences in insulinemia (IRI) displayed a prevalence of maternal obesity in the group with higher levels of basal and stimulated IRI values, which decline after changes in diet and body weight. This behavior of IRI levels and amount and composition of diet indicate a possible permissive role of previous food consumption habits.

Achilles Tendon↗