Biomedical subjects
R Pearson
Publications and source records attributed to R Pearson.
Adverse reactions to drugs.
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Detection of coronavirus-like particles from mink with epizootic catarrhal gastroenteritis.
Coronavirus-like particles have been detected by electron microscopy in fecal samples from naturally occurring cases of epizootic catarrhal gastroenteritis (ECG) of mink. Preliminary transmission trials with bacteria-free filtrates from mink with ECG suggested that a coronavirus plays a role in the disease syndrome.
Radiography in women of childbearing ability.
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Students for higher education.
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Information skills still in demand.
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Sex linked juvenile retinoschisis with optic disc and peripheral retinal neovascularisation.
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Wanted--doctors who care.
A study was conducted to determine what consumers value in doctors' behavior. Results indicate that consumers in the sample population studied prefer doctors who are friendly and caring as well as those who are technically competent. However, these respondents reported less favorable opinions about doctors' friendliness (i.e., affective behavior) than they did about doctors' competence (i.e., instrumental behavior).
Rapid assessment procedures are changing the way UNICEF evaluates its projects.
The Rapid Assessment Procedure establishes a link between information and decision-making by focusing on why and how problems occur.
Mycobacterium tuberculosis pneumonia in two HIV antibody positive patients.
The acquired immunodeficiency syndrome is associated with the development of opportunistic infections. We report the cases of two HIV antibody positive male partners who developed pneumonia responding to antituberculous therapy.
Rabbit anti-thymocyte globulin treatment of steroid resistant rejection in renal allograft recipients immunosuppressed with cyclosporine A.
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Neodymium: YAG laser iridotomies--short-term comparison with capsulotomies and long-term follow-up.
This study addresses three aspects of anterior segment Nd:YAG laser treatment--acute endothelial damage, as assessed by endothelial specular photomicrography (ESP), acute and long-term intraocular pressure (IOP) changes, and long-term iridotomy patency. The acute ESP and IOP changes in 26 eyes (21 patients) after Nd:YAG laser iridotomies were compared to 39 eyes (37 patients) after Nd:YAG laser capsulotomy. Similar endothelial damage occurred in both groups, although less damage was noted in the group of 9 eyes in which capsulotomies were undertaken in the presence of an intraocular lens. In a parallel study 53 eyes (44 patients) were followed for a mean of 83 weeks (19 months) from the time of Nd:YAG iridotomy. There were no late closures and no late rises in IOP. The level of acute IOP rise after treatment did not predict long-term IOP. We conclude that Nd:YAG iridotomy is an effective procedure in the long-term, and that both iridotomy and capsulotomy are accompanied by noteworthy acute endothelial changes and intraocular pressure rises.
Giardiasis in Alabama. Diagnosis and treatment.
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Imaging rounds #95. Atypical infection: osteoarticular sporotrichosis.
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Unusual remission of Pneumocystis carinii pneumonia in a patient with the acquired immune deficiency syndrome.
Pneumocystis carinii is a well-recognized cause of pneumonia in patients with immune deficiency, and when untreated, mortality approaches 100 percent. Although rare cases suggesting spontaneous recovery (usually accompanied by resolving immune deficiency) have been reported, spontaneous resolution of P. carinii pneumonia in patients with the acquired immune deficiency syndrome (AIDS) has not been described. A patient with AIDS in whom Pneumocystis pneumonia developed and remitted without appropriate therapy is described. This case suggests that the immunologic defects of AIDS are not fixed and that fluctuations in the degree of immunocompetence may allow for clinical recovery from opportunistic infections associated with AIDS even without appropriate therapy.
Comparisons of feline panleukopenia virus, canine parvovirus, raccoon parvovirus, and mink enteritis virus and their pathogenicity for mink and ferrets.
Parvoviruses from mink (mink enteritis virus [MEV]), cats (feline panleukopenia virus [FPV]), raccoons (raccoon parvovirus [RPV]), and dogs (canine parvovirus [CPV]) were compared. Restriction enzyme analysis of the viral replicative-form DNA revealed no consistent differences between FPV and RPV isolates, but CPV and MEV isolates could be distinguished readily from other virus types. Feline panleukopenia virus, RPV, and MEV, but not CPV, replicated to high titers in mink. However, on the first passage, disease and microscopic lesions were observed only in mink inoculated with MEV. Feline panleukopenia virus and RPV isolates replicated in ferrets, but disease or microscopic lesions were not observed. Feline panleukopenia virus and RPV isolates could be passaged repeatedly in mink and ferrets. Virulence of FPV and RPV isolates was low compared with that of MEV, and only a single mink inoculated with FPV or with RPV developed clinical disease on the sixth passage of virus.
Smoking in hospital--a survey of staff attitudes at Westminster Hospital.
A survey of staff attitudes to smoking and facilities for smokers and non-smokers at Westminster Hospital and associated buildings revealed widespread support for firmer measures to limit and control smoking on health service premises. The survey was eventually undertaken with the agreement of staff side union representatives who had initially resisted the health authority's wish to implement a policy on smoking. In the event, the results provided support to the TUC's 1981 Resolution calling for increased smoking restrictions in workplaces as part of an overall policy to reduce smoking prevalence among working people, which has been followed up in local initiatives by unions throughout the country.