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Biomedical subjects

R Ono

Publications and source records attributed to R Ono.

At least 91 records · Page 5Linked to original sources

Clinical experience with the 22-MeV microtron at the National Cancer Center Hospital.

Experience with the 22-MeV microtron is presented. The maintenance and ease of operability of the system are satisfactory. The physical characteristics showed many clinical advantages. Fundamental measurement of dose distribution and depth dose curves were performed and clinically applied. The two-gantry system is very satisfactory and effective for irradiation by photons and electrons to treat many patients per day. The facility for intraoperative radiotherapy and the physical conditions for total body irradiation are also sufficient because of the well-designed building layout and the systematized facility with the microtron system.

Humans↗

[Occurrence of carcinoma of the vulva and vagina following irradiation of cervix carcinoma].

Six patients with carcinoma of the vulva and 3 with carcinoma of the vagina following radiation therapy for cancer of the cervix were analyzed. The interval between irradiation and diagnosis of the second tumor varied from 5 to 23 years. Despite the lack of having detailed information on irradiation factors in all patients, circumstantial evidence from this study suggests that radiation therapy may have contributed to the development of carcinoma of the vulva and vagina in some of the patients. Close follow-up patients treated for squamous carcinoma of the genital tract must emphasize inspection for new lesions. The incidences previously reported in the literature are also reviewed for comparison.

Aged↗

[Primary malignant tumors in the lung and larynx --a report of 37 cases].

For the past 20 years (from May 1962 to December 1982) the cases of lung cancer and laryngeal cancer treated in National Cancer Center Hospital are 2423 and 603 respectively. We have studied multiple cases of the lung and laryngeal cancers. The cigarette smoking is one of the most important environmental factors concerning the multiple cases of laryngeal and lung cancer would not be so significant in the future, if the cigarette smoking factor should be excluded.

Adult↗

[Extra-abdominal desmoid tumor--report of a case].

A case of an extra-abdominal desmoid tumor in a 17-year-old female is reported. At the time of the first examination, the tumor was found to already involve the floor of the mouth, the submandibular region, both sides of the neck, the anterior chest wall and the mediastinum and hence was considered inoperable. The patient was treated by external irradiation and interstitial irradiation (Ir and Au). The therapeutic response was very slow, becoming noticeable 4 months after completion of the therapy and lasting for more than a year. Experience in this case indicates that in order for radiotherapy to prove successful in the treatment of desmoid tumor, it must be administered in relatively high doses. Since desmoid tumors reportedly have the potential for sarcomatous transformation, a long-term follow-up seems to be necessary in the management of patients with this neoplasm. It is considered that inoperable extra-abdominal desmoid tumors are a good indication for radiation therapy.

Adolescent↗

[Bronchography].

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Bronchography↗

Bronchofiberscopy with curette biopsy and bronchography in the evaluation of peripheral lung lesions.

Flexible bronchofiberscopy using a double-hinged curette biopsy and under fluoroscopic guidance was performed on 46 patients with peripheral lung carcinomas smaller than 2 cm. Prior mapping of the location of the lung lesion was achieved with selective peripheral bronchography. With these diagnostic tools, a positive cytologic diagnosis for lung carcinomas was made in 45 of 46 patients, a yield of 97.8 percent. Complications associated with the curette biopsy included minor bleeding in three cases and pneumothorax requiring a chest tube in one case.

Adult↗