Letter: Assessment of cadaveric kidneys for transplantation.
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Biomedical subjects
Publications and source records attributed to R M Taylor.
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The use of cholic acid T tube infusion and of the Burhenne catheter has been investigated in the management of gallstones retained in the common bile duct following biliary surgery in 9 patients. Four of 7 patients treated with cholic acid infusion showed disappearance of the stones during treatment. The stones in a fifth subject were removed by a combination of cholic acid infusion (1 stone disappeared) and instrumentation with a Burhenne catheter (a second stone removed). Use of a Burhenne catheter was unsuccessful in 3 of 4 patients. Details of the technique of cholic acid infusion are given, and possible complications of the treatment are discussed. The use of cholic acid infusion for the dissolution of stones in the common bile duct is recommended.
Ergonomic principles have seldom been applied to the design of maps for use in aviation. Maps are not usually evaluated as displays of information, and the contents of maps often do not match the needs of the user. Most maps are visually so complex that it is not immediately apparent whether standard recommendations for the coding and display of information apply to them. Methods for evaluating maps have to be devised, and comparisons made between subjective and objective measures. A series of experiments has considered the content of maps in relation to the needs of the users, and has examined new methods for presenting information on maps, with a view to increasing the efficiency of map communication.
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Thirty-two human cadaver kidneys were assessed by continuous perfusion before transplantation. Altogether, 26 were transplanted. Ten kidneys functioned immediately, of which nine had excellent renal function at three months. Sixteen had delayed onset of function, of these only five had excellent function at three months. There was no difference in warm ischaemic interval between the two groups or in ice storage time. The immediate function group, however, were perfused for twice as long as the delayed function group. The two groups could not be separated on donor history, but they could be precisely separated during perfusion by measuring lactic acidosis and lactic acid dehydrogenase (LDH). The biggest single difference between the groups was in terms of donor preparation.
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