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Biomedical subjects

R Loire

Publications and source records attributed to R Loire.

At least 217 records · Page 12Linked to original sources
PubMed1980

[Pulmonary xanthogranulomas (author's transl)].

The authors report on six cases of pulmonary xanthogranuloma. They stress the latent character of these dense, round isolated parenchymatous tumors. The tumors have an homogeneous aspect without calcifications and regional adenopathies. The radio-clinical diagnosis is difficult to assess because the para-clinical examinations are regularly negative. The differential diagnosis is made either clinically, especially with hamartochondroma and peripheral cancer, or histologically according to the predominance of various types of cells, especially with a solitary plasmocytoma, a lymphoma or a sclerosant hemangioma. Histology is the only key to diagnosis. For these reasons, the decision for surgical intervention presents a problem as the patients, often young, present no visible signs and the lesions evolve but very slowly.

Adolescent↗
PubMed1979

[Myocardial protection by perfusion in deep hypothermia (10 degrees C) with or without cardioplegia (author's transl)].

A technique of myocardial protection using a perfusion circuit in deep hypothermia via the ascending aorta or by selective cannulation of the coronaries has been used over a period of 2 years in almost 200 patients undergoing surgery requiring prolonged aortic clamping. It ensures rapid and homogeneous cooling of the myocardium (10-12 degrees C) and meets its reduced oxygen needs. It may be completed by cardioplegia (infusion of potassium chloride or lidocaine using an automatic syringe at a determined level). This simple technique permits a rapid spontaneous return of normal effective cardiac action. No low cardiac output syndromes have been seen since it has been used. Laboratory, histological, biochemical and haemodynamic studies carried out have confirmed its harmless nature.

Cardiac Surgical Procedures↗
PubMed1979

[Anomaly of the origin of the circumflex artery. Effects on the risk of mitral and mitro-aortic valve replacement].

An anomalous circumflex coronary artery arising from the main right coronary artery is an added risk in mitro-aortic valve replacement. The infortunate history of a patient with an anomalous circumflex artery visualised on pre-operative cineangiography who underwent a double valve replacement is reported. The first 10 post-operative days were uncomplicated with no haemodynamic disturbances. Thereafter, major ventricular arrhythmiad 54th post-operative days) without signs of myocardial infarction, which were responsible for her death. On autopsy a large anomalous circumflex artery arising from the main right coronary artery was shown. In its course, posterior to the aorta, it was literally wedged between the rigid sewing rings of the two prosthetic valves. No thrombus was found within, and there were no myocardial lesions. The only apparent cause of the arrhythmias and death of the patient was the compression of this large circumflex artery.

Adult↗
PubMed1979

[Mediastinal bronchogenic cysts in adults. Cardiovascular symptomatology (author's transl)].

The authors describe seven patients operated upon for mediastinal bronchogenic cysts and emphasize the problems of differential diagnosis from cardiac and vascular affections: enlarged left auricle and aneurysm of the thoracic aorta. They review the published literature on atypical bronchogenic cysts with cardiac or vascular symptoms, and the diagnostic problems they raise in adults.

Adult↗
PubMed1979

[Sarcoma of the right superior pulmonary vein: physiopathological study of the progressive stenosis in a lobar vein (author's transl)].

A part from the interest aroused by the exceptional nature of this case of sarcoma of the right superior pulmonary vein, it enabled definition of the angiographic appearances of the affection of the vein. Physiopathological examinations, including vascular redistribution, development of a systemic collateral circulation, and the reflux of hematosed blood into the pulmonary trunk, were able to establish the diagnosis in vivo.

Collateral Circulation↗
PubMed1978

[The myocardiopathies of dermatomyositis and periarteritis nodosa].

Myocardial involvement was indicated by isolated findings (especially on the ECG) without corresponding functional disorders in one third of cases of dermatomyositis. Rapidly fatal heart failure occurred rarely in this disease, and was noteworthy for a QS complex in the central precordial leads, and for the presence of intracardiac thromboses which could give rise to emboli. Terminal cardiac failure was the rule in cases of periarteritis nodosa, which is a much rarer disease; this occurrence was secondary to hypertension. The most characteristic lesions were nodular coronary arteritis and disseminated myocarditis due to the arteriolar lesions.

Cardiomyopathies↗
PubMed1978

[The myocardiopathies of systemic lupus erythematosus].

Myocardial involvement in lupus erythematosis takes the form of an interstitial myocarditis with cellular infiltration and fibrinoid necrosis. The most lesions are perivascular, and involve the arterioles. The myocardial fibres are involved secondarily to the vascular lesions, or by grossly, damaging sclerosis. The clinical features are variable:--no clinical features, but haemodynamic evidence of abnormal ventricular function, and perhaps sudden death;--arrhythmias and disorders of atrio-ventricular conduction;--cardiac failure, which may be due to a genuine cardiomyopathy (a part may be played by hypertension, pulmonary hypertension, renal failure, constrictive pericarditis or haemodynamically major valve disorders);--abnormalities of the coronary trunk in a certain number of cases. If anti-nuclear antibodies are present in a cardiomyopathy, the presence of DLE or of a drug-induced lupus syndrome must be suspected. There remain some awkward cases which defy classification, and which systematic use of echocardiography and pericardial and myocardial biopsy may be able to define more accurately.

Antibodies, Antinuclear↗
PubMed1978

[The sclerodermic myocardiopathies].

Sclerodermic cardiomyopathy is the commonest cardiac lesion in this collagen disorder. The picture is a common-place one of left ventricular failure with moderate cardiomegaly (unless there is an associated chronic pericardial effusion). There are no characteristic features on the ECG. The prognosis is particularly poor, with death within one or two years. Clinical presentation of the cardiomyopathy may be preceded by isolated ECG changes occuring over one or two years. The myocardial disorder, which is often associated with latent pericardial and endocardial lesions, is peculiar to scleroderma out of all the collagen disorders, but presents no difficulty in differential diagnosis because of the other features of the disease of which it is a part.

Adult↗